The ALS Therapy Development Institute (ALS TDI), Answer ALS, and Microsoft are pleased to announce a collaboration that will bring together the two largest existing clinical and omics data sets relating to ALS. Through this partnership, comprehensive data collected through ALS TDI’s ALS Research Collaborative (ARC) will be added to Neuromine, an innovative data portal launched in 2021 by Answer ALS and powered by Microsoft Azure. By nearly doubling the amount of data available through Neuromine, this groundbreaking collaboration can accelerate ALS research worldwide. With these two massive dat ..read more

Our 2022 4th quarter newsletter is available here. There has been a lot to celebrate, but there is so much more work to do. Please read about what the researchers supporting and utilizing Answer ALS samples and data have been working on to bring an end to the disease. https://conta.cc/3X0cjgZ The post The Answer ALS 2022 4th Quarter News & Updates appeared first on Answer ALS ..read more

ALS Motor Neurons Differ by Sex, Study Finds. A new Cedars-Sinai study in collaboration with the University of California, Irvine (UCI) and the Answer ALS consortium has examined the expression of thousands of genes in stem cell-generated motor neurons that are known to die in patients with ALS. The study, published in the peer-reviewed journal Neuron, revealed sex was one of the main drivers of different gene expression in motor neurons, regardless of whether they were from patients diagnosed with ALS or controls. Read the entire study here: http://bit.ly/3J6yldG The post Large-scale differen ..read more

Answer ALS is excited to announce Danielle Boyce, DPA, MPH as the new Executive Director for Answer ALS Research, coupled with her roles as Executive Director for the Packard Center, and Assistant Professor of Neurology at Johns Hopkins. Danielle brings 20-years of experience as a researcher, patient advocate, public speaker and author. “Danielle is a long-term and well-versed advocate for ALS patients and research,” said Jeffrey Rothstein , M.D., Ph.D., Founder and Director of the Robert Packard Center. “Her background in data and project management along with her passionate drive for the adv ..read more

A new set of rich Answer ALS project data is now available through the Answer ALS Data Portal NEW ORLEANS, October 21, 2021 (Newswire.com) – A new set of Answer ALS project data is now available through the Answer ALS Data Portal. This data release is another milestone reaching 63% of the total estimated 150 TB of data that will be generated and openly shared. This massive trove of data from multiple biological assessments or “multi-omics” has been combined with study participants’ clinical data and is now publicly released. The datasets are all derived from individual Answer ALS study pa ..read more

In honor of Lou Gehrig’s Day on June 2nd and of Gehrig’s famous speech on July 4th, we will draw one name to be given a Lou Gehrig signed baseball. For every $50 donated at the link below, you will be entered once. If you are able to donate $100 or $200, you will be given more chances for this baseball history! The more you give to help ALS research, the more chances you have! You can also enter once, by emailing Giving@AnswerALS.org and stating: “Please enter me in the Lou Gehrig Baseball Giveaway”. Also, add your name and phone number. We will draw for the new owner of the baseball on July ..read more

NEW ORLEANS, January 8, 2021 (Newswire.com) – Answer ALS, in cooperation with the Stephen Hawking Foundation, launches “The Data is Here” campaign on January 8 and on what would have been the famed Theoretical Physicist’s 79th birthday. The campaign features a video tribute to Stephen Hawking and his tireless efforts to solve complex universal questions, while living with ALS for over 50 years. Although he and science were unable to unravel the mystery of ALS in his lifetime, the campaign boldly states, “At 21, Stephen Hawking was diagnosed with ALS. In ’21, we aim to make a breakthr ..read more

A new set of Answer ALS project data is now available through the Answer ALS Data Portal! The release is a milestone not only for the program but for the field of ALS research in general. This is the first time that data from multiple biological assessments (so-called “multi-omics”) have been combined with clinical data and publicly released. The datasets, which include clinical, transcriptomic, and epigenomic sequence data, are all derived from individual Answer ALS study participants. The release also incorporates data portal updates to help with downstream analysis. The newly released  ..read more

FORT WORTH, Texas — American Airlines raised more than $1.2 million for Answer ALS this week through its annual Charity Golf Tournament presented by Citi. “We are honored to continue our partnership with Answer ALS and support them on their way to raising $45 million for this critical, first of its kind, research project,” said Chairman and CEO Doug Parker. “Many of our team members have been impacted by ALS, and we hope that by bringing attention to ALS, we can raise further awareness and fundraising support to help find a cure.” ALS, or amyotrophic lateral sclerosis, is a progressive neurod ..read more

The first set of Answer ALS study data is now available to request at data.answerals.org. Just two months after reaching our target enrollment of 1000 participants, this release includes whole genome sequence data paired with full clinical profiles from the first 100 study participants. As profiles are completed, they will be added until the entire trove of data is available to the global ALS research community. Datasets can be searched based on both clinical and sample features allowing all researchers to rapidly identify the most relevant information for their own studies. The post Ans ..read more