TropicalMed, Vol. 9, Pages 93: Evaluation of Segmentation, Rotation, and Geographic Delivery Approaches for Deployment of Multiple First-Line Treatment (MFT) to Respond to Antimalarial Drug Resistance in Africa: A Qualitative Study in Seven Sub-Sahara Countries Tropical Medicine and Infectious Disease doi: 10.3390/tropicalmed9050093 Authors: Celine Audibert Adam Aspinall Andre-Marie Tchouatieu Pierre Hugo Background: Several studies recently confirmed the emergence of resistance to antimalarial drugs in sub-Saharan Africa. Multiple first-line treatment (MFT) is one of the measures envisaged to ..read more

TropicalMed, Vol. 9, Pages 89: Prevalence of Drug-Resistant Tuberculosis in HIV-Positive and Diabetic Patients in Sinaloa, Mexico: A Retrospective Cross-Sectional Study Tropical Medicine and Infectious Disease doi: 10.3390/tropicalmed9040089 Authors: Analy Aispuro Pérez Ulises Osuna-Martínez Jose Angel Espinoza-Gallardo Luis Alfredo Dorantes-Álvarez Gerardo Kenny Inzunza-Leyva Kimberly Estefania Dorantes-Bernal Geovanna Nallely Quiñonez-Bastidas Tuberculosis (TB) is a disease caused by the bacillus Mycobacterium tuberculosis (MTB). Human immunodeficiency virus (HIV) infection and type 2 diabet ..read more

TropicalMed, Vol. 9, Pages 90: Spatiotemporal Analysis of Malaria Transmission in the Autonomous Indigenous Regions of Panama, Central America, 2015–2022 Tropical Medicine and Infectious Disease doi: 10.3390/tropicalmed9040090 Authors: Alberto Cumbrera José Eduardo Calzada Luis Fernando Chaves Lisbeth Amarilis Hurtado Despite ongoing efforts for elimination, malaria continues to be a major public health problem in the Republic of Panama. For effective elimination, it is key that malaria foci and areas of high transmission are identified in a timely manner. Here, we study malaria tran ..read more

TropicalMed, Vol. 9, Pages 91: Comparative Study of Colorimetric In Situ Hybridization and Quantitative Real-Time Polymerase Chain Reaction for Diagnosis of Infection by Leishmania infantum in Dogs in Formalin-Fixed and Paraffin-Embedded Skin Tropical Medicine and Infectious Disease doi: 10.3390/tropicalmed9040091 Authors: Ricardo Gonçalves Silva Matti Kiupel Ingeborg Maria Langohr Annabel Wise Sandro Antonio Pereira Natália Pedra Gonçalves Greice Maria Silva da Conceição Luiz Cláudio Ferreira Monique Paiva de Campos Luciana de Freitas Campos Miranda Fabiano Borges Figueiredo Raquel de Vasconc ..read more

TropicalMed, Vol. 9, Pages 88: Plasma Circulating Cell-Free DNA Facilitated the Detection of an Alveolar Echinococcosis Patient Initially Misdiagnosed as Cystic Echinococcosis: A Case Report Tropical Medicine and Infectious Disease doi: 10.3390/tropicalmed9040088 Authors: Yanping Zhao Yiyang Shi Shu Shen Yan Zhang Gengfu Wei Xin Jin Echinococcosis, especially alveolar echinococcosis (AE), is becoming an emerging/re-emerging disease with a growing number of cases reported globally. The diagnosis of echinococcosis is based mainly on imaging, which may be challenging when the image presentation i ..read more

TropicalMed, Vol. 9, Pages 86: Impact of the SARS-CoV-2 Pandemic on the Management and Prognosis of Infective Endocarditis Tropical Medicine and Infectious Disease doi: 10.3390/tropicalmed9040086 Authors: Lucie Ailhaud Robinson Gravier-Dumonceau Florent Arregle Sandrine Hubert Jean-Paul Casalta Alberto Riberi Laetitia Tessonnier Roch Giorgi Gilbert Habib Frédérique Gouriet Background: Infective endocarditis (IE) is a serious condition which is difficult to diagnose and to treat, both medically and surgically. Objectives: The objective of this study was to evaluate the impact of the SARS-CoV-2 ..read more

TropicalMed, Vol. 9, Pages 87: Global, Regional and National Burden of Human Cystic Echinococcosis from 1990 to 2019: A Systematic Analysis for the Global Burden of Disease Study 2019 Tropical Medicine and Infectious Disease doi: 10.3390/tropicalmed9040087 Authors: Tian Tian Liyuan Miao Wei Wang Xiaonong Zhou Background: Cystic echinococcosis (CE) is a neglected tropical parasitic disease that poses huge disease, social and economic burdens worldwide; however, there has been little knowledge on the global morbidity, mortality and disability-adjusted life years (DALYs) of CE until now. This stu ..read more

TropicalMed, Vol. 9, Pages 85: Sigma-Class Glutathione Transferases (GSTσ): A New Target with Potential for Helminth Control Tropical Medicine and Infectious Disease doi: 10.3390/tropicalmed9040085 Authors: Lluvia de Carolina Sánchez Pérez Rafael A. Zubillaga Ponciano García-Gutiérrez Abraham Landa Glutathione transferases (GSTs EC 2.5.1.18) are critical components of phase II metabolism, instrumental in xenobiotics’ metabolism. Their primary function involves conjugating glutathione to both endogenous and exogenous toxic compounds, which increases their solubility and ..read more

TropicalMed, Vol. 9, Pages 83: Splenic Embolism in Infective Endocarditis: A Systematic Review of the Literature with an Emphasis on Radiological and Histopathological Diagnoses Tropical Medicine and Infectious Disease doi: 10.3390/tropicalmed9040083 Authors: Gabriel Santiago Moreira Nícolas de Albuquerque Pereira Feijóo Isabella Braga Tinoco-da-Silva Cyntia Mendes Aguiar Francijane Oliveira da Conceição Gustavo Campos Monteiro de Castro Mariana Giorgi Barroso de Carvalho Thatyane Veloso de Paula Amaral de Almeida Rafael Quaresma Garrido Cristiane da Cruz Lamas Infective endocarditis (IE) is c ..read more

TropicalMed, Vol. 9, Pages 81: Capturing Recent Mycobacterium tuberculosis Infection by Tuberculin Skin Test vs. Interferon-Gamma Release Assay Tropical Medicine and Infectious Disease doi: 10.3390/tropicalmed9040081 Authors: Jesús Gutierrez Mary Nsereko LaShaunda L. Malone Harriet Mayanja-Kizza Hussein Kisingo W. Henry Boom Charles M. Bark Catherine M. Stein Reductions in tuberculosis (TB) incidence require identification of individuals at high risk of developing active disease, such as those with recent Mycobacterium tuberculosis (Mtb) infection. Using a prospective household contact (HHC) s ..read more