Infectious Diseases: Research and Treatment, Volume 15, Issue , January-December 2022. Background:A Soil-transmitted helminthic infection (STHIs) remains a notable health problem in resource-limited countries.Objective:This systematic review and meta-analysis aimed to determine the overall prevalence of STH infections in Ethiopia.Methods:Articles written in English were searched from online public databases. Searching terms taken separately and jointly were “prevalence,” “soil-transmitted helminths” “nematode,” “Geo-helminths,” “roundworm,” “Necator,” “Ancylostoma,” “Ascaris,” “Trichuris,” “ho ..read more

Infectious Diseases: Research and Treatment, Volume 15, Issue , January-December 2022. Background:Malaria is a public health problem, particularly in low- and middle-income countries. In Angola, it is the leading cause of death, morbidity, and absenteeism from work and school.Objective:To evaluate the social and clinical factors associated with resistance to in-hospital treatment.Methodology:A prospective analytical cross-sectional study with a quantitative approach was conducted including 220 patients with malaria.Results:Of the 220 patients enrolled, the majority were between 21 and 40 years ..read more

Infectious Diseases: Research and Treatment, Volume 15, Issue , January-December 2022. Background:Healthcare-associated infection (HAI) is an important public health problem, particularly in intensive care units (ICUs). We aimed to examine the epidemiology and risk factors of HAIs in our ICUs and study their microbiological profile.Methods:We evaluated 100 consecutive patients in 3 medical and surgical ICUs of a tertiary care teaching hospital daily starting in January 2016 using the Centers for Disease Control and Prevention definitions and methods. We determined the incidence and sites of HA ..read more

Infectious Diseases: Research and Treatment, Volume 15, Issue , January-December 2022. Introduction:Citrobacter spp. is an opportunistic bacteria that have been recognized as significant pathogens in patients with underlying diseases or immunocompromised status. The aim of this study was to identify extended-spectrum β-lactamases in clinical isolates of Citrobacter spp.Methods:This cross-sectional study was conducted at Hospital Central “Dr. Ignacio Morones Prieto” in San Luis Potosi, Mexico. Nineteen isolates of Citrobacter spp. were obtained from clinical specimens between April to December ..read more

Infectious Diseases: Research and Treatment, Volume 15, Issue , January-December 2022. Background:Healthcare providers are in high occupational risk of Hepatitis B virus infection than that of the general population because of the high risk of occupational exposure to patients’ body fluids and accidental sharp injuries. There are no large facility-based studies conducted on the prevalence of HBV infection and its associated factors among health care providers in eastern Ethiopia.Objective:This study aimed at investigating the seroprevalence of Hepatitis B Virus and its associated factors among ..read more

Infectious Diseases: Research and Treatment, Volume 14, Issue , January-December 2021. Background:Methicillin Resistant Staphylococcus aureus (MRSA) is a significant human pathogen associated with nosocomial infections. mecA in the S. aureus is a marker of MRSA. The main objective of this study was to detect mecA and vanA genes conferring resistance in S. aureus among cardiac patients attending Sahid Gangalal National Heart Centre (SGNHC), Kathmandu, Nepal between May and November 2019.Methods:A total of 524 clinical samples (blood, urine, sputum) were collected and processed. Bacterial isolat ..read more

Infectious Diseases: Research and Treatment, Volume 14, Issue , January-December 2021. As the world continues to respond to the coronavirus pandemic (COVID-19), there is a larger hidden threat of antimicrobial resistance (AMR) lurking behind. AMR remains worrisome in that the pathogens causing resistant infections to thrive in hospitals and medical facilities, putting all patients at risk, irrespective of the severity of their medical conditions, further compounding the management of COVID-19. This study aims to provide overview of early findings on COVID-19 and AMR as well as to provide recom ..read more

Infectious Diseases: Research and Treatment, Volume 14, Issue , January-December 2021. The literature on bloodstream infections (BSIs) have predominantly been biased towards bacteria, given their superior clinical significance in comparison with the other types of microorganisms. Fungal pathogens have epidemiologically received relatively less attention, although they constitute an important proportion of BSI aetiologies. In this review, the authors discuss the clinical relevance of fungal BSIs in the context of Candida species, as well as treatment options for the infections, emphasizing the ..read more

Infectious Diseases: Research and Treatment, Volume 14, Issue , January-December 2021. Earlier in its course, SARS-CoV-2 was primarily identified to cause an acute respiratory illness in adults, the elderly and immunocompromised, while children were known to be afflicted with milder symptoms. However, since mid-April of 2020, latent effects of the virus have begun emerging in children and adolescents, which is characterised by a multisystem hyperinflammatory state; thus, the term Multisystem Inflammatory Syndrome in Children (MIS-C) was introduced by the WHO and CDC. The syndrome manifests its ..read more

Infectious Diseases: Research and Treatment, Volume 14, Issue , January-December 2021. Background:National consensus guidelines outline recommendations for best practices in treating patients with candidemia. This study evaluated the impact of receiving care adherent to the best practice recommendations on clinical outcomes in patients with candidemia.Methods:This retrospective, multicenter study included patients with candidemia from 2010 to 2015 at 9 hospitals. The primary outcome was the composite of 30-day in-hospital mortality and 90-day candidemia recurrence. Outcomes were compared betwe ..read more