For decades, the idea that you could attack genetic illnesses right at the root — that you could modify people's genes to treat or cure disease — sounded like science fiction. But in recent years, several new gene therapy treatments have been FDA approved, and many others are showing promise in clinical trials. On this episode, we take a look at what's new with gene therapy, what's on the horizon, and the challenges standing in the way. We hear stories about making these treatments more affordable by changing the manufacturing process, what happened when one family tried to enroll their son in ..read more

What we make for dinner, grab as a snack, or have for breakfast changes all the time — and there are some major forces at play: consumer tastes and marketing, but also climate change, global supply chains, nutrition science, health concerns, and social media influencers. On this episode, we'll look at what we eat and why. We'll find out how lima beans are getting a makeover, and why seed oils ended up becoming a lightning rod in nutrition debates. We'll also taste a futuristic green with self-proclaimed superpowers, meet one physician who's trying to convince people to eat more organ meats, a ..read more

Sugary cereals for breakfast, a protein bar as a snack, a microwave lasagna for lunch, and a frozen pizza for dinner sounds like a teenager's dream diet, but these are the types of foods physician Chris van Tulleken ate for four weeks. During this time, he got 80 percent of his daily calories from ultra-processed foods, to see how it would impact his health and mood. He writes about this experience, and his extensive research on these products in his new book, "Ultra-Processed People: The Science Behind Food That Isn't Food." Host Maiken Scott talks to Van Tulleken about the link to obesity an ..read more

In March of 2022, the war in Ukraine was weighing heavily on Fabian Falch, a Norwegian tech entrepreneur. The Russian government had started to censor news stories and social media posts about the war, and Falch wondered how Russian citizens would be able to access information, let alone voice criticism. Then he had an idea: to send emails to Russians — millions of them. Eventually, a conflict researcher got involved in this effort and it turned into a real-time study on what works and what doesn't when it comes to shifting people's perspectives. On this episode, we explore what we have learn ..read more

Rejection, or even the thought of it, can strike fear into our hearts, and leave a bad taste in our mouths. It often leads to a mix of sadness, shame, anxiety, and anger — along with nagging questions. What's wrong with me? Why did this person not like me? Why didn't I win this award? Why didn't I get the job? But it doesn't have to be that way, and there's a lot we can learn from not making the cut. On this episode, we explore the experience of rejection — what it feels like, how it functions, and the lessons we can draw from it.We'll hear from a fear and anxiety researcher about the evolutio ..read more

For most of the big moments in life, we have rituals — proposals, weddings, births, graduations, and anniversaries. We know how to talk about them, how to celebrate them, how to honor them. But there's one moment we all face that lots of people don't know how to deal with: dying. In fact, a majority of Americans avoid end-of-life planning, even though most say it's important. Losing a loved one — not to mention facing your own mortality — is a hard reality to contemplate. So how do we go about having those tough conversations about the end of life? Is there a "right" way to talk about it? Can ..read more

Flying saucers, little green men, and the X-Files — for years, that's what most people associated with unidentified flying objects, or UFOs. They were the stuff of sci-fi and supermarket tabloids, conspiracy theories and punchlines.But ever since a bombshell article in The New York Times several years back documented confirmed sightings by navy pilots, UFOs — or UAPs, unidentified aerial phenomena, as they've been rebranded — have been slowly migrating into the mainstream.Today, it's not uncommon to find scientists, elected officials, and decorated members of the military talking publicly abou ..read more

Dealing with a serious or chronic health condition is hard enough — but what happens when that condition comes with moral judgment? That's the case for millions of people around the world. From obesity to lung cancer, sexually transmitted diseases to mental illness, stigmatized conditions are shrouded in shame and blame that can not only hinder treatment — but ruin lives. On this episode, we explore stigmatized health conditions — how they earn their reputations, affect the lives of patients, and complicate efforts to treat them. We hear about the flawed effort to track down the origin of the ..read more

Most of us have been there — feeling our jeans get tighter, watching the numbers on the scale creep up, declaring that this time we're going to lose the weight and keep it off. For a lot of people, though, it seems like no matter what they do — how many diets they try, calories they count, or hours they spend at the gym — losing weight isn't just hard; it feels downright impossible. Two in five American adults are obese, and the numbers keep rising. It's been called a public health crisis, especially since obesity can lead to a number of other health issues, like heart disease and diabetes ..read more

It sneaks up on us while we're sitting in traffic, or waiting at the doctor's office, or doing our taxes — boredom, that restless feeling of dissatisfaction that arises when we harbor "the desire for desires," as Leo Tolstoy said. At the same time, we're living in an age of never-ending stimulation, all at our fingertips — texting, social media, 24-hour news, and streaming galore. But despite this constant content consumption, we're still getting bored — maybe even more so than ever. We find ourselves hopping from tab to tab, scrolling through Instagram while watching a show, tuning out of me ..read more