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BioMed Central » Immunity & Ageing

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Immunity & Ageing is a specialist open-access journal dedicated to increasing knowledge about the impact of aging on immune systems, the influence of aged immune systems on organismal well-being and longevity, and the potential for interventions to increase health span. At BMC, we are committed to continual innovation to better support the needs of our communities, ensuring the integrity of..

Correction: The impact of ageing on the distribution of preformed anti-HLA and anti-MICA antibody specificities in recipients from eastern China prior to initial HSCT

BioMed Central » Immunity & Ageing

by Qinqin Pan, Xiao Ma, Yajie You, Yuejiao Yu, Su Fan, Xiaoyan Wang, Mengyuan Wang, Ming Gao, Guangming Gong, Kourong Miao, Jie Shen and Xiaoyu Zhou

1w ago

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Role of germinal center and CD39highCD73+ B cells in the age-related tonsillar involution

BioMed Central » Immunity & Ageing

by Rocío Pastor, Juliana Puyssegur, M. Paula de la Guardia, Lindybeth Sarmiento Varón, Gladys Beccaglia, Nicolás Spada, Andrea Paes de Lima, M. Soledad Collado, Andrés Blanco, Isabel Aspe Scetti, M. Elena Arabolaza, Bibiana Paoli, Fernando Chirdo and Eloísa Arana

1w ago

The tonsils operate as a protection ring of mucosa at the gates of the upper aero-digestive tract. They show similarities with lymph nodes and participate as inductive organs of systemic and mucosal immunity ..read more

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Changes in the innate immune response to SARS-CoV-2 with advancing age in humans

BioMed Central » Immunity & Ageing

by Sudhanshu Agrawal, Michelle Thu Tran, Tara Sinta Kartika Jennings, Marlaine Maged Hosny Soliman, Sally Heo, Bobby Sasson, Farah Rahmatpanah and Anshu Agrawal

1M ago

Advancing age is a major risk factor for respiratory viral infections. The infections are often prolonged and difficult to resolve resulting hospitalizations and mortality. The recent COVID-19 pandemic has hig ..read more

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Immune profiles of pre-frail people living with HIV-1: a prospective longitudinal study

BioMed Central » Immunity & Ageing

by Lucy Kundura, Renaud Cezar, Sandrine Gimenez, Manuela Pastore, Christelle Reynes, Albert Sotto, Jacques Reynes, Clotilde Allavena, Laurence Meyer, Alain Makinson and Pierre Corbeau

1M ago

People living with HIV (PLWH) are at risk of frailty, which is predictive for death. As an overactivity of the immune system is thought to fuel frailty, we characterized the immune activation profiles linked t ..read more

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Excess of body weight is associated with accelerated T-cell senescence in hospitalized COVID-19 patients

BioMed Central » Immunity & Ageing

by Mailton Prestes Madruga, Lucas Kich Grun, Letícya Simone Melo Dos Santos, Frederico Orlando Friedrich, Douglas Bitencourt Antunes, Marcella Elesbão Fogaça Rocha, Pedro Luis Silva, Gilson P. Dorneles, Paula Coelho Teixeira, Tiago Franco Oliveira, Pedro R.T. Romão, Lucas Santos, José Claudio Fonseca Moreira, Vinicius Schenk Michaelsen, Marcelo Cypel, Marcos Otávio Brum Antunes…

1M ago

Several risk factors have been involved in the poor clinical progression of coronavirus disease-19 (COVID-19), including ageing, and obesity. SARS-CoV-2 may compromise lung function through cell damage and par ..read more

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Immune aging in annual killifish

BioMed Central » Immunity & Ageing

by Gabriele Morabito, Alina Ryabova and Dario Riccardo Valenzano

1M ago

Turquoise killifish (Nothobranchius furzeri) evolved a naturally short lifespan of about six months and exhibit aging hallmarks that affect multiple organs. These hallmarks include protein aggregation, telomere s ..read more

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Correction: Obesity-induced neuroinflammation and cognitive impairment in young adult versus middle-aged mice

BioMed Central » Immunity & Ageing

by Rosemary E. Henn, Sarah E. Elzinga, Emily Glass, Rachel Parent, Kai Guo, Adam M. Allouch, Faye E. Mendelson, John Hayes, Ian Webber-Davis, Geoffery G. Murphy, Junguk Hur and Eva L. Feldman

2M ago

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Ageing on the impact of distribution about preformed anti-HLA and anti-MICA antibody specificities in recipients prior to initial HSCT from East China

BioMed Central » Immunity & Ageing

by Qinqin Pan, Xiao Ma, Yajie You, Yuejiao Yu, Su Fan, Xiaoyan Wang, Mengyuan Wang, Ming Gao, Guangming Gong, Kourong Miao, Jie Shen and Xiaoyu Zhou

2M ago

With the development of Hematopoietic Stem Cell Transplantation (HSCT) technology, increasing numbers of elderly patients were undergoing allogeneic HSCT and elderly patients with hematologic malignancies coul ..read more

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The interplay between obesity, immunosenescence, and insulin resistance

BioMed Central » Immunity & Ageing

by Ghazaleh Shimi, Mohammad Hassan Sohouli, Arman Ghorbani, Azam Shakery and Hamid Zand

2M ago

Obesity, which is the accumulation of fat in adipose tissue, has adverse impacts on human health. Obesity-related metabolic dysregulation has similarities to the metabolic alterations observed in aging. It has ..read more

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The role of NLRP3 inflammasome in aging and age-related diseases

BioMed Central » Immunity & Ageing

by Ruikai Liang, Xinrui Qi, Qi Cai, Liyan Niu, Xi Huang, Deju Zhang, Jitao Ling, Yuting Wu, Yixuan Chen, Pingping Yang, Jianping Liu, Jing Zhang and Peng Yu

2M ago

The gradual aging of the global population has led to a surge in age-related diseases, which seriously threaten human health. Researchers are dedicated to understanding and coping with the complexities of agin ..read more

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