BioMed Central » Immunity & Ageing
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Immunity & Ageing is a specialist open-access journal dedicated to increasing knowledge about the impact of aging on immune systems, the influence of aged immune systems on organismal well-being and longevity, and the potential for interventions to increase health span. At BMC, we are committed to continual innovation to better support the needs of our communities, ensuring the integrity of..
BioMed Central » Immunity & Ageing
1w ago
Dementia and frailty are common age-related syndromes often linked to chronic inflammation. Identifying the biological factors and pathways that contribute to chronic inflammation is crucial for developing new ..read more
BioMed Central » Immunity & Ageing
2w ago
Age-related declines in immune response pose a challenge in combating diseases later in life. Influenza (flu) infection remains a significant burden on older populations and often results in catastrophic disab ..read more
BioMed Central » Immunity & Ageing
3w ago
Pain in Fabry disease (FD) is generally accepted to result from neuronal damage in the peripheral nervous system as a consequence of excess lipid storage caused by alpha-galactosidase A (α-Gal A) deficiency. S ..read more
BioMed Central » Immunity & Ageing
3w ago
Current influenza vaccines deliver satisfactory results in young people but are less effective in the elderly. Development of vaccines for an ever-increasing aging population has been an arduous challenge due ..read more
BioMed Central » Immunity & Ageing
3w ago
Morphological and functional alterations in aging reproductive organs result in decreased male fertility. The epididymis functions as the transition region for post-testicular sperm maturation. And we have pre ..read more
BioMed Central » Immunity & Ageing
3w ago
Age-related accumulation of highly differentiated CD8+ effector memory re-expressing CD45RA (EMRA) T-cells and disruption of the kynurenine (KYN) pathway are associated with chronic inflammation and the developme ..read more
BioMed Central » Immunity & Ageing
1M ago
Aging is associated with progressive declines in immune responses leading to increased risk of severe infection and diminished vaccination responses. Influenza (flu) is a leading killer of older adults despite ..read more
BioMed Central » Immunity & Ageing
1M ago
Immunosenescence is a complex process characterized by an age-related remodelling of immune system. The prominent effects of the immunosenescence process is the thymic involution and, consequently, the decreas ..read more
BioMed Central » Immunity & Ageing
2M ago
A wide spectrum of changes occurs in the brain with age, from molecular to morphological aspects, and inflammation accompanied by mitochondria dysfunction is one of the significant factors associated with age ..read more
BioMed Central » Immunity & Ageing
2M ago
The aging lungs are vulnerable to chronic pulmonary diseases; however, the underlying mechanisms are not well understood. In this study, we compared the aging lungs of 20–24-month-old mice with the young of 10 ..read more