The impact of inflammatory bowel diseases on the quality of life of Saudi pediatric patients: A cross-sectional study
Saudi Journal of Gastroenterology
by Abdulhamid A Alhadab, Shaden N AlMahamed, Ibrahim E Hassan, Abdelhai H Hammo
2w ago
Abdulhamid A Alhadab, Shaden N AlMahamed, Ibrahim E Hassan, Abdelhai H Hammo Saudi Journal of Gastroenterology 2022 28(6):448-455 Background: Inflammatory bowel disease (IBD) is a chronic gastrointestinal tract disorder characterized by periods of exacerbations and remissions that affect multiple aspects of a pediatric patient's quality of life. The purpose of this study is to describe the health-related quality of life of Saudi pediatric IBD patients and to determine the influencing factors which can affect it. Methods: This is a single center cross-sectional descriptive study, cond ..read more
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Aberrant DNA methylation and expression of EYA4 in gastric cardia intestinal metaplasia
Saudi Journal of Gastroenterology
by Chenxi Li, Zhaohui Liu, Guohua Xu, Shibin Wu, Yunhui Peng, Ruinuan Wu, Shukun Zhao, Xiaoqi Liao, Runhua Lin
2w ago
Chenxi Li, Zhaohui Liu, Guohua Xu, Shibin Wu, Yunhui Peng, Ruinuan Wu, Shukun Zhao, Xiaoqi Liao, Runhua Lin Saudi Journal of Gastroenterology 2022 28(6):456-465 Background: Intestinal metaplasia (IM) of the gastric cardia is an important premalignant lesion. However, there is limited information concerning its epidemiological and molecular features. Herein, we aimed to provide an overview of the epidemiological data for gastric cardiac IM and evaluate the role of EYA transcriptional coactivator and phosphatase 4 (EYA4) as an epigenetic biomarker for gastric cardiac IM. Methods: The study was ..read more
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Oxidative stress and the importance of H. pylori eradication in patients with functional dyspepsia
Saudi Journal of Gastroenterology
by Berat Ebik, Nihat Aslan, Nazım Ekin, Ferhat Bacaksiz, Medeni Arpa, Salim Neselioglu, Ozcan Erel, Feyzullah Ucmak
2w ago
Berat Ebik, Nihat Aslan, Nazım Ekin, Ferhat Bacaksiz, Medeni Arpa, Salim Neselioglu, Ozcan Erel, Feyzullah Ucmak Saudi Journal of Gastroenterology 2022 28(6):434-440 Background: To investigage the thiol and disulphide levels in Helicobacter pylori-positive patients with non-ulcer dyspepsia and investigate the change in these levels with eradication therapy. Methods: This is a prospective observational study. A total of 320 patients diagnosed with dyspepsia according to Rome IV criteria were included in the study. First, blood samples were drawn from patients to determine their serum ..read more
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Comparison of the diagnostic accuracy of the updated Sydney system and single biopsy
Saudi Journal of Gastroenterology
by Cundullah Torun, Arda Yavuz, Kubra Akan, Hatice Seneldir, Ayse Nur Toksoz, Hak Celal Ulasoglu, Ilyas Tuncer
2w ago
Cundullah Torun, Arda Yavuz, Kubra Akan, Hatice Seneldir, Ayse Nur Toksoz, Hak Celal Ulasoglu, Ilyas Tuncer Saudi Journal of Gastroenterology 2022 28(6):441-447 Background: Updated Sydney system (USS) recommends taking biopsies from certain areas of the stomach for the diagnosis of precancerous lesions associated with Helicobacter pylori. Our aim was to evaluate the contribution of each of the biopsy sites to the diagnosis. Methods: This prospective study included 97 patients aged 40 and over with dyspeptic complaints. Biopsies were taken from five regions: the lesser curvature of the antrum ..read more
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Transient elastography for the prevalence of non-alcoholic fatty liver disease in patients with type 2 diabetes: Evidence from the CORDIAL cohort study
Saudi Journal of Gastroenterology
by Assim A Alfadda, Suphia M Sherbeeni, Adel N Alqutub, Abdullah S Aldosary, Nasser M Aldaghri, Simon D Taylor-Robinson, Saleh A Alqahtani, Rukhsana Gul, Abdulrahman M Almaghamsi
2w ago
Assim A Alfadda, Suphia M Sherbeeni, Adel N Alqutub, Abdullah S Aldosary, Nasser M Aldaghri, Simon D Taylor-Robinson, Saleh A Alqahtani, Rukhsana Gul, Abdulrahman M Almaghamsi Saudi Journal of Gastroenterology 2022 28(6):426-433 Background: Non-alcoholic fatty liver disease (NAFLD) is highly prevalent in patients with type 2 diabetes mellitus (T2DM). This study aimed to investigate the prevalence of NAFLD among Saudi patients with T2DM using transient elastography. Methods: A total of 490 patients with T2DM who attended diabetes and primary care clinics were recruited. Controlled attenuation ..read more
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Cholecystectomy reduces the severity of subsequent idiopathic acute pancreatitis
Saudi Journal of Gastroenterology
by Jing Lei, Feng Xu, Haiyan Cao, Zhihang Zhou, Song He
2w ago
Jing Lei, Feng Xu, Haiyan Cao, Zhihang Zhou, Song He Saudi Journal of Gastroenterology 2022 28(6):417-425 Background: Acute pancreatitis (AP) is a common digestive system disease, and its incidence is increasing year by year. Although some clinical studies have indicated that cholecystectomy can reduce the risk of recurrent pancreatitis after acute biliary pancreatitis (ABP), it is not clear whether cholecystectomy would affect the severity of subsequent AP. Methods: In this study, we combined computed tomography scoring index (CTSI), bedside index for severity in AP (BISAP), and clinical ma ..read more
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Cholecystectomy for idiopathic acute pancreatitis: Not yet there!
Saudi Journal of Gastroenterology
by Nitin Jagtap, Sundeep Lakhtakia
2w ago
Nitin Jagtap, Sundeep Lakhtakia Saudi Journal of Gastroenterology 2022 28(6):401-402 ..read more
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Fluctuating hepatitis B viremia: Full of sound and fury, signifying nothing?
Saudi Journal of Gastroenterology
by Henry H Nguyen, Samuel S Lee
3M ago
Henry H Nguyen, Samuel S Lee Saudi Journal of Gastroenterology 2022 28(5):319-321 ..read more
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Intestinal microbiota profile in healthy Saudi children: The bacterial domain
Saudi Journal of Gastroenterology
by Mohammad El Mouzan, Abdulrahman A Al-Hussaini, Ahmed Al Sarkhy, Asaad Assiri, Mona Alasmi
5M ago
Mohammad El Mouzan, Abdulrahman A Al-Hussaini, Ahmed Al Sarkhy, Asaad Assiri, Mona Alasmi Saudi Journal of Gastroenterology 2022 28(4):312-317 Background: Knowledge of microbiota in health is essential for clinical research on the role of microbiota in disease. We aimed to characterize the intestinal microbiota in healthy Saudi children. Methods: In this community-based study, stool samples were collected from a randomly selected sample of 20 healthy school children of Saudi origin. The samples were frozen at –80°C till analysis. Bacterial DNA was isolated and libraries we ..read more
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Effect of Portulaca Oleracea L. extract on functional constipation: A randomized, double-blind, placebo-controlled trial
Saudi Journal of Gastroenterology
by Ki Bae Bang, Jung Ho Choi, Jee Hun Park, Seong Lee, Mun-Chual Rho, Seung W Lee, Soyoung Lee, Jeong Eun Shin
5M ago
Ki Bae Bang, Jung Ho Choi, Jee Hun Park, Seong Lee, Mun-Chual Rho, Seung W Lee, Soyoung Lee, Jeong Eun Shin Saudi Journal of Gastroenterology 2022 28(4):296-303 Background: This study aimed to investigate the efficacy of P. oleracea in the management of patients with functional constipation. Methods: A total of 60 patients with functional constipation as defined by the Rome IV criteria were enrolled in this randomized, double-blind, placebo-controlled study; 70% ethanol extracts of the aerial parts of P. oleracea were used for the intervention. Patients were randomly assigned to the ..read more
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