In a large claims-based analysis, prevalence of IBS in pregnant and postpartum patients was 1.38%. Psychological comorbidities were more prevalent in pregnant and postpartum patients with IBS compared to those without. Abstract Background There is a lack of data on the epidemiology of IBS in pregnant and postpartum patients in the United States. Methods A retrospective claims analysis was conducted in a cohort of 1,618,379 patients with ≥1 delivery hospitalization between 2013–2019 utilizing ICD-9 and ICD-10 codes after merging inpatient and outpatient claims. Obstetric, psychological, and o ..read more

General disordered eating behaviors and orthorexia symptoms are common in patients with IBS and occur at similar rates to people with a diagnosed eating disorder. Clinicians should consider the characteristics identified when prescribing dietary therapies. Abstract Introduction Orthorexia, a harmful obsession with eating healthily, may develop from illnesses characterized by dietary restriction, including irritable bowel syndrome (IBS) and eating disorders (ED). Evidence of disordered eating in IBS exists, but orthorexia has not been assessed. This cross-sectional study in adults (≥18 years ..read more

The prevalence of most extra-intestinal symptoms is higher among patients with IBS-M. Characterization of IBS subtypes could potentially help refining tailored therapeutic strategies based on the systemic symptom profile. Abstract Background Irritable bowel syndrome (IBS) is a functional disorder commonly associated with extra-intestinal symptoms. However, the prevalence of these symptoms according to IBS subtype is not well established. Aim To compare the prevalence of extra-intestinal symptoms among patients with different subtypes of IBS. Methods A descriptive cross-sectional study includ ..read more

A strict diet without all kinds of fermentable food on the day before the test decreases significantly the baseline values of breath hydrogen and methane, compared to a diet without dietary fibers. Glucose breath tests results are less frequently positive with a strict diet on the day before the test. Abstract Background Glucose breath test (GBT) is used for the diagnosis of small intestine bacterial overgrowth. A restrictive diet without fibers and/or fermentable food is recommended on the day before the test. The aim of our retrospective study was to evaluate the impact of two different re ..read more

Reflux esophagitis is commonly observed within 1 year after peroral endoscopic myotomy (POEM) and is severe (grade C/D) in 1 out of 10 patients. Recognizing risk factors for reflux esophagitis after POEM is imperative to select patients for POEM and to take appropriate preventive measures. Abstract Background Peroral endoscopic myotomy (POEM) is an effective and safe treatment for achalasia, but often leads to posttreatment gastroesophageal reflux disease. The aim of this study was to examine the incidence and severity of reflux esophagitis after POEM and to identify associated predictive fa ..read more

The functional lumen imaging probe (FLIP) is a test of anal sphincter distensibility however two measurement protocols are in use, risking a lack of standardization. In patients with fecal incontinence, differences exist between these two protocols at rest, therefore consensus agreement is required to agree the most appropriate protocol. Abstract Background The functional lumen imaging probe (FLIP) is a test of anal sphincter distensibility under evaluation by specialist centers. Two measurement protocols termed “stepwise” and “ramp” are used, risking a lack of standardization. This study ai ..read more

Rumination, the repeated and effortless regurgitation of food, is more common in adults than in children. In adults, rumination is associated with female gender, anxiety, and depression. Abstract Background Rumination is characterized by the repeated regurgitation of food. Rumination syndrome is a disorder of gut-brain interaction diagnosed by Rome criteria, whereas rumination disorder is a feeding and eating disorder diagnosed by DSM-5 criteria. We aimed to determine the global prevalence of rumination according to these criteria across all age groups. Methods We performed a systematic revi ..read more

75.6% of patients with disorders of gut–brain interaction with chronic diarrhea reported postprandial diarrhea (PPD). This is associated with more severe GI symptoms and decreased quality of life. Female sex and CCY predict PPD, while psychological factors do not. Abstract Background and Aims Postprandial diarrhea (PPD) is commonly seen in patients with disorders of gut–brain interaction (DGBI), but the factors associated with it have not been well studied. In this study, we aim to study the burden, impact, and predictors of PPD using a clinical cohort of DGBI patients. Methods This study in ..read more

The Pediatric Version of the Gugging Swallowing Screen (GUSS) has a discriminant ability to detect the risk of aspiration in children with dysphagia. It implies the same diagnostic accuracy and applicability as the original version for adults. Pediatric version of GUSS adds value to the scientific community and especially in the field of speech pathology for the bedside evaluation of pediatric dysphagia. Abstract Background The Gugging Swallowing Screen (GUSS) is a bedside dysphagia screening tool that has been designed to determine the risk of aspiration in acute stroke patients. There is n ..read more

Patients with restrictive lung disease are more likely to show improvement in esophageal motility than patients with obstructive disease following lung transplantation. Effects on gastroesophageal reflux are more complex and difficult to predict because of contributory factors, such as motility, anatomical differences (e.g., esophageal length), and lung mechanics (e.g., TAPG). Abstract Background For many patients with lung disease the only proven intervention to improve survival and quality of life is lung transplantation (LTx). Esophageal dysmotility and gastroesophageal reflux (GER) are c ..read more