Evaluation of guidelines for diagnosis and treatment of Helicobacter pylori infection
Helicobacter
by Yan‐Hong Ji, Yan‐Mei Shi, Qian‐Wen Hei, Jin‐Min Sun, Xiao‐Feng Yang, Tao Wu, Da‐Li Sun, Yu‐Xing Qi
6d ago
Abstract Background To systematically evaluate the quality of the guidelines for the diagnosis and treatment of Helicobacter pylori infection and to analyze the differences and reasons for the key recommendations in the guidelines. Methods Databases and websites were systematically searched to obtain guidelines for the diagnosis and treatment of Helicobacter pylori infection. Four independent reviewers used the Guideline Evaluation Tool (AGREE II) to evaluate the included guidelines. The intraclass correlation coefficient (ICC) and Fleiss' kappa coefficient were used to measure the consistency ..read more
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Bismuth, esomeprazole, metronidazole and amoxicillin or tetracycline as a first‐line regimen for Helicobacter pylori eradication: A randomized controlled trial
Helicobacter
by Xue‐li Tian, Bao‐jun Suo, Hua Zhang, Hao‐ping Lu, Cai‐ling Li, Yu‐xin Zhang, Xin‐lu Ren, Xing‐yu Yao, Li‐ya Zhou, Zhi‐qiang Song
1w ago
Abstract Background Due to general unavailability and common side effects of tetracycline, the clinical application of bismuth quadruple therapy (BQT) is greatly limited. Whether amoxicillin can replace tetracycline in BQT remains unknown. This study aimed to compare the eradication rate, safety and compliance between amoxicillin-containing and tetracycline-containing BQT as a first-line regimen for Helicobacter pylori eradication. Methods This randomized trial was conducted on 404 naïve patients for H. pylori eradication. The participants were randomly assigned to 14-day amoxicillin-containin ..read more
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2w ago
Helicobacter, Volume 27, Issue 6, December 2022 ..read more
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Histopathologically defined intestinal metaplasia in lesser curvature of corpus prior to Helicobacter pylori eradication is a risk factor for gastric cancer development
Helicobacter
by Daichi Hara, Takuma Okamura, Yugo Iwaya, Tadanobu Nagaya, Hiroyoshi Ota, Takeji Umemura
1M ago
Abstract Background and Aim Helicobacter pylori eradication has been shown to reduce the risk of gastric cancer (GC), with the number of eradication therapy cases on the rise. However, GC can still occur after successful treatment, and the histological differences prior to eradication in patients with and without GC are unclear. This study investigated the pre-treatment histological risk factors for GC development following eradication therapy. Methods We retrospectively enrolled consecutive adult patients diagnosed as having H. pylori infection between April 2004 and December 2018. Atrophy an ..read more
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Clinical evaluation of a novel molecular diagnosis kit for detecting Helicobacter pylori and clarithromycin‐resistant using intragastric fluid
Helicobacter
by Momoko Tsuda, Yoshiyuki Watanabe, Ritsuko Oikawa, Ryosuke Watanabe, Masayuki Higashino, Kimitoshi Kubo, Hiroyuki Yamamoto, Fumio Itoh, Mototsugu Kato
1M ago
Abstract Background Although there are many Helicobacter pylori (H. pylori) diagnostic methods, the culture and antibiotic susceptibility test is an important method for selecting the most effective H. pylori eradication regimen. However, this diagnostic method is complicated and takes several days; therefore, the development of a rapid and simple diagnostic method is required. Eradication failure due to clarithromycin (CAM) resistance should also be considered. In this study, we report the clinical evaluation of point-of-care testing (POCT) kit using intragastric fluid, a novel kit ..read more
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REAP‐HP survey 2020: Comparing the real‐world practice and expectation in Helicobacter pylori eradication of the Taiwanese gastroenterologists in 2015 and 2020
Helicobacter
by Yoen‐Young Chuah, Deng‐Chyang Wu, Seng‐Kee Chuah, Kuan‐Yang Chen, Jyh‐Chin Yang, Chia‐Long Lee, Chien‐Lin Chen, Sz‐Iuan Shiu, Chang‐Bih Shie, Chih‐An Shih, Feng‐Woei Tsay, Yu‐Hwa Liu, Ping‐I Hsu, for the Taiwan Acid‐related Disease & Microbiota Consortium (TARD‐M)
2M ago
Abstract Background REAP-HP study (Real-world practice and Expectation of Asia-Pacific physicians and patients in Helicobacter Pylori eradication) was the pioneer study investigating the expectation and preference of physicians across Asia-Pacific in H. pylori eradication in 2015. This study is the first follow-up study of REAP-HP in Taiwan. Aims (1) To investigate the preference in regimens for the first-line anti-H. pylori therapy of Taiwanese gastroenterologist in 2020, (2) To survey the factor that cause the most concern when prescribing anti-H. pylori regimens in clinical p ..read more
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Efficacy of bismuth for antibiotic‐resistant Helicobacter pylori strains eradication: A systematic review and meta‐analysis
Helicobacter
by Zhongxue Han, Yueyue Li, Qingzhou Kong, Jing Liu, Juan Wang, Meng Wan, Minjuan Lin, Boshen Lin, Wenlin Zhang, Yuming Ding, Shaotong Wang, Yijun Mu, Miao Duan, Xiuli Zuo, Yan‐qing Li
2M ago
Abstract Background & Aims Antibiotic resistance of Helicobacter pylori (H. pylori) is increasing worldwide, and bismuth quadruple therapy has been recommended as a first-line regimen in many areas. This study aimed to investigate whether bismuth would improve the eradication rate (ER) of clarithromycin-/metronidazole-/levofloxacin-resistant H. pylori strains and how much additional efficacy bismuth could achieve. Methods PubMed, EMBASE, Web of Science, and Cochrane Central databases for randomized controlled trials were systematically searched by two independent reviewers until ..read more
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Perspectives from recent advances of Helicobacter pylori vaccines research
Helicobacter
by Ying Zhang, Xiaoya Li, Baoen Shan, Hongtao Zhang, Lianmei Zhao
2M ago
Abstract Background Helicobacter pylori (H. pylori) infection is the main factor leading to some gastric diseases. Currently, H. pylori infection is primarily treated with antibiotics. However, with the widespread application of antibiotics, H. pylori resistance to antibiotics has also gradually increased year by year. Vaccines may be an alternative solution to clear H. pylori. Aims By reviewing the recent progress on H. pylori vaccines, we expected it to lead to more research efforts to accelerate breakthroughs in this field. Materials & Methods We searched the research on H. pylori vacci ..read more
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Issue Information
Helicobacter
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2M ago
Helicobacter, Volume 27, Issue 5, October 2022 ..read more
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Helicobacter
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2M ago
Helicobacter, Volume 27, Issue 5, October 2022 ..read more
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