GastroHep
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GastroHep is an international, peer-reviewed, quality publication focussing on current and cutting-edge research in academic and clinical gastroenterology and hepatology. GastroHep provides the platform for submissions of articles of interest to the practicing clinician and research workers and academic staff in all aspects of gastroenterology and hepatology. Its aim is to help disseminate..
GastroHep
2y ago
ABSTRACT Introduction & Objective
Mortality data from high income group countries are frequently used in developing countries for healthcare planning. This study was planned to explore the mortality pattern of cirrhosis in India in terms of survival after diagnosis of cirrhosis, predictors of death and etiology specific effect on mortality.
Methods
This observational study enrolled newly diagnosed patients with liver disease (n=3193) attending a tertiary care hospital in Kolkata, India between April 2010 and October 2012 and were followed up to September, 2015.
Results
Patients with cirrho ..read more
GastroHep
2y ago
Abstract Background
Helicobacter pylori (H.pylori) assessment in patients who stop taking proton pump inhibitor (PPI) in less than 2 weeks has never been established. Experts have suggested using pathology rather than rapid urease test (RUT). Unfortunately, pathology is not widely available in limited resource areas. We aimed to evaluate the detection rate of RUT at antrum and body compared with pathology in those patients.
Methods
Sixty-seven patients with history of PPI use for at least 2 weeks and continued use within 2 weeks prior to gastroscopy were enrolled. Two biopsies were taken from ..read more
GastroHep
2y ago
Abstract Background
Liver stiffness (LS) as measured by magnetic resonance elastography (MRE) and the presence of intrahepatic non-hypervascular hypointense nodules (NHHNs) during the hepatobiliary phase of gadolinium-ethoxybenzyl diethylenetriamine-pentaacetic acid–enhanced magnetic resonance imaging are non-invasive MR-based biomarkers of hepatocarcinogenesis.
Methods
We retrospectively evaluated the ability of these two MR-based biomarkers to stratify the risk of hepatocellular carcinoma (HCC) development in patients with chronic liver disease. Between September 2013 and April 2020, 868 con ..read more
GastroHep
2y ago
SUMMARY Background
Helicobacter pylori infection affects ~35% of Americans and may lead to serious sequelae if left untreated, including gastric cancer. Obesity is a significant risk factor for antibiotic treatment failure; however, little work has been done to understand the influence of high body mass index (BMI) on the success rates of H. pylori eradication regimens in treatment-naïve and refractory adult patients.
Aim
This analysis evaluated the association of subject obesity on overall H. pylori eradication rates for RHB-105 (rifabutin, amoxicillin, and omeprazole magnesium; Talicia®) and ..read more
An updated incidence of paediatric achalasia and number of myotomies performed in the United Kingdom
GastroHep
2y ago
Abstract Background
Achalasia is a rare condition characterised by an absent oesophageal peristalsis and non-relaxing lower oesophageal sphincter. The incidence of paediatric achalasia is poorly studied and inconsistently reported. We aimed to provide an up to date incidence of paediatric achalasia in the UK
Methods
All United Kingdom hospitals with paediatric gastroenterology and/or paediatric surgery were contacted to provide data on achalasia diagnosis and myotomies performed (2008 – 2020). Hospital Episode Statistics (HES) includes diagnostic and procedural data for all hospitals in Englan ..read more