Application of image-recognition techniques to automated micronucleus detection in the in vitro micronucleus assay
Genes and Environment
by Hiromi Yoda, Kazuya Abe, Hideya Takeo, Takeji Takamura-Enya and Ayumi Koike-Takeshita
1d ago
An in vitro micronucleus assay is a standard genotoxicity test. Although the technique and interpretation of the results are simple, manual counting of the total and micronucleus-containing cells in a microsco ..read more
Visit website
Astaxanthin suppresses the malignant behaviors of nasopharyngeal carcinoma cells by blocking PI3K/AKT and NF-κB pathways via miR-29a-3p
Genes and Environment
by Yajia Xu and Chengyi Jiang
4d ago
As a natural extraction, astaxanthin is gaining increasing attention because of its safety and anti-tumor properties. It has been reported to participate in the progression of various types of cancer such as g ..read more
Visit website
Correction: The spectrum of TP53 mutations in Rwandan patients with gastric cancer
Genes and Environment
by Augustin Nzitakera, Jean Bosco Surwumwe, Ella Larissa Ndoricyimpaye, Schifra Uwamungu, Delphine Uwamariya, Felix Manirakiza, Marie Claire Ndayisaba, Gervais Ntakirutimana, Benoit Seminega, Vincent Dusabejambo, Eric Rutaganda, Placide Kamali, François Ngabonziza, Rei Ishikawa, Belson Rugwizangoga, Yuji Iwashita…
3w ago
..read more
Visit website
The spectrum of TP53 mutations in Rwandan patients with gastric cancer
Genes and Environment
by Augustin Nzitakera, Jean Bosco Surwumwe, Ella Larissa Ndoricyimpaye, Schifra Uwamungu, Delphine Uwamariya, Felix Manirakiza, Marie Claire Ndayisaba, Gervais Ntakirutimana, Benoit Seminega, Vincent Dusabejambo, Eric Rutaganda, Placide Kamali, François Ngabonziza, Rei Ishikawa, Belson Rugwizangonga, Yuji Iwashita…
1M ago
Gastric cancer is the sixth most frequently diagnosed cancer and third in causing cancer-related death globally. The most frequently mutated gene in human cancers is TP53, which plays a pivotal role in cancer ini ..read more
Visit website
Correction: NCAPD2 is a favorable predictor of prognostic and immunotherapeutic biomarker for multiple cancer types including lung cancer
Genes and Environment
by Linyuan Feng, Yang Yang, Zhenhua Lin, Minghua Cui, Aihua Jin and Aili Cui
2M ago
..read more
Visit website
Understanding exposomes and its relation with cancer risk in Malaysia based on epidemiological evidence: a narrative review
Genes and Environment
by Razinah Sharif and Theng Choon Ooi
2M ago
The prevalence of cancer is increasing globally, and Malaysia is no exception. The exposome represents a paradigm shift in cancer research, emphasizing the importance of a holistic approach that considers the ..read more
Visit website
CDK4/6 inhibitor-induced bone marrow micronuclei might be caused by cell cycle arrest during erythropoiesis
Genes and Environment
by Yuki Okada, Satsuki Chikura, Takafumi Kimoto and Takeshi Iijima
3M ago
A micronucleus test is generally used to evaluate the genotoxic potential of chemicals. Exaggerated erythropoiesis, as occurs following bleeding, may induce an unexpected increase in micronucleus frequency. Th ..read more
Visit website
Curcumin piperidone derivatives induce caspase-dependent apoptosis and suppress miRNA-21 expression in LN-18 human glioblastoma cells
Genes and Environment
by Nur Syahirah Che Razali, Kok Wai Lam, Nor Fadilah Rajab, A. Rahman A. Jamal, Nurul Farahana Kamaludin and Kok Meng Chan
3M ago
Previously, we have reported on the two curcuminoid analogues with piperidone derivatives, namely FLDP-5 and FLDP-8 have more potent anti-proliferative and anti-migration effects than curcumin. In this study ..read more
Visit website
Metformin suppresses proliferation and glycolysis of gastric cancer by modulating ADAMTS12
Genes and Environment
by Rui Chen, Jianhui Chen, Miaoliang Chen, Shenkang Zhou and Pinlu Jiang
4M ago
Gastric cancer (GC) is a common malignancy with its morbidity increasing worldwide. Hence, it is imperative to develop effective treatments. Studies have shown that metformin has potential antitumor effects. T ..read more
Visit website
NCPAD2 is a favorable predictor of prognostic and immunotherapeutic biomarker for multiple cancer types including lung cancer
Genes and Environment
by Linyuan Feng, Yang Yang, Zhenhua Lin, Minghua Cui, Aihua Jin and Aili Cui
4M ago
Non-SMC condensin I complex subunit D2 (NCAPD2) belongs to the chromosomal structural maintenance family. While the different contribution of NCAPD2 to chromosome in mitosis have been thoroughly investigated ..read more
Visit website

Follow Genes and Environment on FeedSpot

Continue with Google
Continue with Apple
OR