Look4LTRs: a Long terminal repeat retrotransposon detection tool capable of cross species studies and discovering recently nested repeats
Mobile DNA
by Anthony B. Garza, Emmanuelle Lerat and Hani Z. Girgis
2d ago
Plant genomes include large numbers of transposable elements. One particular type of these elements is flanked by two Long Terminal Repeats (LTRs) and can translocate using RNA. Such elements are known as LTR ..read more
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RepEnTools: an automated repeat enrichment analysis package for ChIP-seq data reveals hUHRF1 Tandem-Tudor domain enrichment in young repeats
Mobile DNA
by Michel Choudalakis, Pavel Bashtrykov and Albert Jeltsch
1w ago
Repeat elements (REs) play important roles for cell function in health and disease. However, RE enrichment analysis in short-read high-throughput sequencing (HTS) data, such as ChIP-seq, is a challenging task ..read more
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Orthoptera-TElib: a library of Orthoptera transposable elements for TE annotation
Mobile DNA
by Xuanzeng Liu, Lina Zhao, Muhammad Majid and Yuan Huang
1M ago
Transposable elements (TEs) are a major component of eukaryotic genomes and are present in almost all eukaryotic organisms. TEs are highly dynamic between and within species, which significantly affects the ge ..read more
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The role of Smarcad1 in retroviral repression in mouse embryonic stem cells
Mobile DNA
by Igor Bren, Ayellet Tal, Carmit Strauss and Sharon Schlesinger
1M ago
Moloney murine leukemia virus (MLV) replication is suppressed in mouse embryonic stem cells (ESCs) by the Trim28-SETDB1 complex. The chromatin remodeler Smarcad1 interacts with Trim28 and was suggested to allo ..read more
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CRISPR-TE: a web-based tool to generate single guide RNAs targeting transposable elements
Mobile DNA
by Yixin Guo, Ziwei Xue, Meiting Gong, Siqian Jin, Xindi Wu and Wanlu Liu
2M ago
The CRISPR/Cas systems have emerged as powerful tools in genome engineering. Recent studies highlighting the crucial role of transposable elements (TEs) have stimulated research interest in manipulating these ..read more
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A systematic screen for co-option of transposable elements across the fungal kingdom
Mobile DNA
by Ursula Oggenfuss, Thomas Badet and Daniel Croll
3M ago
How novel protein functions are acquired is a central question in molecular biology. Key paths to novelty include gene duplications, recombination or horizontal acquisition. Transposable elements (TEs) are inc ..read more
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Evolutionary dynamics of the LTR-retrotransposon crapaud in the Podospora anserina species complex and the interaction with repeat-induced point mutations
Mobile DNA
by Ivar Westerberg, S. Lorena Ament-Velásquez, Aaron A. Vogan and Hanna Johannesson
3M ago
The genome of the filamentous ascomycete Podospora anserina shows a relatively high abundance of retrotransposons compared to other interspersed repeats. The LTR-retrotransposon family crapaud is particularly abu ..read more
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The sixth Japanese meeting on biological function and evolution through interactions between hosts and transposable elements
Mobile DNA
by Kenji Ichiyanagi, Yoko Ikeda and Kuniaki Saito
4M ago
The sixth Japanese meeting on host–transposon interactions, titled “Biological Function and Evolution through Interactions between Hosts and Transposable Elements,” was held on August 24th and 25th, 2023, at t ..read more
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SINE-derived satellites in scaled reptiles
Mobile DNA
by Nikita S. Vassetzky, Sergei A. Kosushkin and Alexey P. Ryskov
4M ago
The genomes of many eukaryotes contain DNA repeats in the form of both tandem and interspersed elements with distinct structure, evolutionary histories, and mechanisms of emergence and amplification. Although ..read more
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An intronic LINE-1 regulates IFNAR1 expression in human immune cells
Mobile DNA
by Carmen A. Buttler, Daniel Ramirez, Robin D. Dowell and Edward B. Chuong
5M ago
Despite their origins as selfish parasitic sequences, some transposons in the human genome have been co-opted to serve as regulatory elements, contributing to the evolution of transcriptional networks. Most we ..read more
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