Probiotics ameliorate endocrine disorders via modulating inflammatory pathways: a systematic review
BioMed Central » Genes & Nutrition
by Marzieh Nemati, Bahareh Ebrahimi and Nima Montazeri-Najafabady
1M ago
Probiotics has offered a new prospect to treat and manage a variety of endocrine disorders such as obesity, diabetes, non- alcoholic fatty liver disease and metabolic syndrome. The precise mechanisms by which ..read more
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Causal relationship between dietary salt intake and dementia risk: Mendelian randomization study
BioMed Central » Genes & Nutrition
by Ke Shi, Yongbo Yu, Zhaolin Li, Miaomiao Hou and Xinyi Li
1M ago
Observational research has indicated a potential link between dietary salt intake and susceptibility to dementia. However, it is important to note that these types of studies are prone to the issues of reverse ..read more
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Tracing vitamins on the long non-coding lane of the transcriptome: vitamin regulation of LncRNAs
BioMed Central » Genes & Nutrition
by Fatemeh Yazarlou, Fatemeh Alizadeh, Leonard Lipovich, Roberta Giordo and Soudeh Ghafouri-Fard
1M ago
A major revelation of genome-scale biological studies in the post-genomic era has been that two-thirds of human genes do not encode proteins. The majority of non-coding RNA transcripts in humans are long non-c ..read more
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The impact of vitamin D on type 2 diabetes management: boosting PTP1B gene expression and physical activity benefits in rats
BioMed Central » Genes & Nutrition
by Kimya Khaledi, Rastegar Hoseini and Ahmad Gharzi
1M ago
The protein tyrosine phosphatase 1B (PTP1B) plays a crucial role in the development of insulin resistance. Aerobic training (AT) and vitamin D (Vit D) supplementation have been shown to individually improve gl ..read more
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Palm-based tocotrienol-rich fraction (TRF) supplementation modulates cardiac sod1 expression, fxr target gene expression, and tauro-conjugated bile acid levels in aleptinemic mice fed a high-fat diet
BioMed Central » Genes & Nutrition
by Nur Aliah Natasha Md Shahrulnizam, Mohd Danial Mohd Efendy Goon, Sharaniza Ab Rahim, Sook Weih Lew, Siti Hamimah Sheikh Abdul Kadir and Effendi Ibrahim
1M ago
Tocotrienol-rich fraction (TRF) has been reported to protect the heart from oxidative stress-induced inflammation. It is, however, unclear whether the protective effects of TRF against oxidative stress involve ..read more
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Genome-wide association study of serum magnesium in type 2 diabetes
BioMed Central » Genes & Nutrition
by Lynette J. Oost, Roderick C. Slieker, Marieke T. Blom, Leen M. ’t Hart, Joost G. J. Hoenderop, Joline W. J. Beulens and Jeroen H. F. de Baaij
3M ago
People with type 2 diabetes have a tenfold higher prevalence of hypomagnesemia, which is suggested to be caused by low dietary magnesium intake, medication use, and genetics. This study aims to identify the ge ..read more
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Dysfunction of DMT1 and miR-135b in the gut-testis axis in high-fat diet male mice
BioMed Central » Genes & Nutrition
by Yanru Zhang, Ruike Ding, Yulin Zhang, Jia Qi, Wenbin Cao, Lijun Deng, Lin Zhou, Yun Ye, Ying Xue and Enqi Liu
3M ago
Obese patients have been found to be susceptible to iron deficiency, and malabsorption of dietary iron is the cause of obesity-related iron deficiency (ORID). Divalent metal transporter 1 (DMT1) and ferroporti ..read more
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From common to rare: repurposing of bempedoic acid for the treatment of glycogen storage disease type 1
BioMed Central » Genes & Nutrition
by Anibh M. Das
7M ago
Hypoketotic hypoglycaemia is a biochemical hallmark of glycogen storage disease type 1 (GSD1). This is due to inhibition of carnitine-palmitoyl transferase 1 by malonyl-CoA. This inhibits the influx of long-ch ..read more
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Causal associations of 25-hydroxyvitamin D with functional gastrointestinal disorders: a two-sample Mendelian randomization study
BioMed Central » Genes & Nutrition
by Senbao Xu, Qiuyan Luo, Jian He, Xiling Chen, Simin Li and Yang Bai
7M ago
Previous observational studies have shown associations between vitamin Ds and FGIDS[Including irritable bowel syndrome(IBS) and functional dyspepsia(FD)]. However, the association is controversial and the caus ..read more
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Coffee consumption and periodontitis: a Mendelian Randomization study
BioMed Central » Genes & Nutrition
by Wan-Zhe Liao, Zhi-Yi Zhou, Zi-Kai Lin, Shuo-Jia Xie, Ya-Fang Zheng, Jun-Tao Wang, Jun-Huang Zheng, Hao-Kai Chen, Wu-Shu Chen and Xu-Guang Guo
7M ago
Coffee is one of the most consumed beverages in the world, coffee consumption has been growing in the United States over the past 20 years. Periodontitis is defined by the pathologic loss of the periodontal li ..read more
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