BMC Medical Genomics
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BMC Medical Genomics is an open access journal publishing original peer-reviewed research articles in all aspects of functional genetics and genomics, genome structure, genome-scale population genetics, epigenetics and epigenomics, proteomics, systems analysis, and pharmacogenomics in relation to human health and disease.
BMC Medical Genomics
2d ago
Acute pancreatitis (AP) is a common systemic inflammatory disease resulting from the activation of trypsinogen by various incentives in ICU. The annual incidence rate is approximately 30 out of 100,000. Some p ..read more
BMC Medical Genomics
5d ago
Repressor element 1 (RE1) silencing transcription factor (REST) is a transcriptional repressor abundantly expressed in aging human brains. It is known to regulate genes associated with oxidative stress, inflam ..read more
BMC Medical Genomics
5d ago
Multilocus pathogenic variants (MPVs) are genetic changes that affect multiple gene loci or regions of the genome, collectively leading to multiple molecular diagnoses. MPVs may also contribute to intrafamilia ..read more
BMC Medical Genomics
5d ago
This study aims to screen the differentially expressed long non-coding RNAs (DELncRNAs) related to the regulation of epithelial-mesenchymal transition (EMT) in hypospadias in mesenchymal stem cell-derived exos ..read more
BMC Medical Genomics
1w ago
Diffuse large B-cell lymphoma (DLBCL), an aggressive and heterogenic malignant entity, is still a challenging clinical problem, since around one-third of patients are not cured with primary treatment. Next-gen ..read more
BMC Medical Genomics
1w ago
Glioblastoma multiforme (GBM) is the most common primary CNS tumor, characterized by high mortality and heterogeneity. However, the related lncRNA signatures and their target microRNA (miRNA) for GBM are still ..read more
BMC Medical Genomics
2w ago
Gamma-glutamyltransferase 5 (GGT5), one of the two members in the GGT family (GGT1 and GGT5), plays a crucial role in oxidative regulation, inflammation promotion, and drug metabolism. Particularly in the tumo ..read more
BMC Medical Genomics
3w ago
Mice are routinely utilized as animal models of drug-induced liver injury (DILI), however, there are significant differences in the pathogenesis between mice and humans. This study aimed to compare gene expres ..read more