There is a special subtype of neuroblastoma seen in very young children, with spread of disease throughout the body, but which needs a very different approach to treatment compared to older children with metastatic disease. This episode explains the features of this stage MS neuroblastoma, the early problems, and the treatment used. Practice link only for now to Patreon See acast.com/privacy for privacy and opt-out information ..read more

If I can be so bold....I wonder if you all might do me a favour, and sponsor my boss for about $1 in a big fundraising walk he is doing. Just a token amount, unless you own oil wells. (One cent will do, if the system allows it!) This might show my hospital administrators that the podcast has an audience who follow it. This episode explains all, and donations are made through https://walkforkidscancer.org.au/ . His particular spot is https://chw.grassrootz.com/bob-tug-wilson-s-walk-for-kids-with-cancer/luciano-dalla-pozza Remember to insert the note 'podcast' in the online form. Thanks!!!!!! Pr ..read more

Childhood cancer treatment leads to severe impairment of the ability to fight infections. This episode explains what immune suppression means, what causes it, and the problems that result. Practice link only for now to Patreon See acast.com/privacy for privacy and opt-out information ..read more

A few years ago I described CAR T-cells, but they weren't available for routine use. I now update things, with the very important news about CAR T-cell therapy now becoming available. There is also an interview with Dr Caroline Bateman re this subject in another episode. Practice link only for now to Patreon See acast.com/privacy for privacy and opt-out information ..read more

We take a lot of blood samples looking for infection in the bloodstream. This episode explains what blood cultures are all about. Practice link only for now to Patreon See acast.com/privacy for privacy and opt-out information ..read more

A number of countries have research studies where childhood cancers are analysed in great detail, testing all the DNA in something called 'molecular profiling'. The national Australian study of this is called PRISM, and it is a very exciting project. This episode explains a molecular profiling project and covers issues of obtaining informed consent from parents and patients as well. Practice link only for now to Patreon See acast.com/privacy for privacy and opt-out information ..read more

The MEK inhibitors are a newer class of drug, and include trametinib, selumetinib and others. They have an important role in paediatric oncology, particularly in glioma treatment and in neurofibromatosis. Practice link only for now to Patreon See acast.com/privacy for privacy and opt-out information ..read more

Sophisticated techniques can detect one cancer cell amongst a million normal cells. This episode describes these methods and how they are used in treatment. Practice link only for now to Patreon See acast.com/privacy for privacy and opt-out information ..read more

CAR T-cell therapy is an exciting new treatment for acute leukaemia. In this episode, Dr Geoff interviews his colleague Dr Caroline Bateman about CAR T-cells and introducing the treatment option to her unit. Practice link only for now to Patreon See acast.com/privacy for privacy and opt-out information ..read more

For many years we didn't biopsy the tumour when the scans suggested that the tumour was a DIPG. This episode explains why that has changed, and the emerging role of biopsy. Practice link only for now to Patreon See acast.com/privacy for privacy and opt-out information ..read more