A prospective cohort study examining the association between the periconceptual vaginal microbiota and first‐trimester miscarriage in Kenyan women
Paediatric and Perinatal Epidemiology
by R. Scott McClelland, Erica M. Lokken, John Kinuthia, Sujatha Srinivasan, Barbra A. Richardson, Walter Jaoko, Sophia Lannon, Anne Pulei, Tina L. Fiedler, Matthew M. Munch, Sean Proll, Grace John‐Stewart, David N. Fredricks
2w ago
Abstract Background Studies evaluating the association between the vaginal microbiota and miscarriage have produced variable results. Objective This study evaluated the association between periconceptual and first-trimester vaginal microbiota and women's risk for miscarriage. Methods At monthly preconception visits and at 9–12 weeks gestation, women collected vaginal swabs for molecular characterisation of the vaginal microbiota. Participants who became pregnant were followed to identify miscarriage versus pregnancy continuing to at least 20 weeks gestation. Results Forty-five women experience ..read more
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Sexual orientation disparities in gestational diabetes and hypertensive disorders of pregnancy
Paediatric and Perinatal Epidemiology
by Payal Chakraborty, Bethany G. Everett, Colleen A. Reynolds, Tabor Hoatson, Jennifer J. Stuart, Sarah C. McKetta, Kodiak R. S. Soled, Aimee K. Huang, Jorge E. Chavarro, A. Heather Eliassen, Juno Obedin‐Maliver, S. Bryn Austin, Janet W. Rich‐Edwards, Sebastien Haneuse, Brittany M. Charlton
2w ago
Abstract Background Sexual minority (SM) individuals (e.g., those with same-sex attractions/partners or who identify as lesbian/gay/bisexual) experience a host of physical and mental health disparities. However, little is known about sexual orientation-related disparities in gestational diabetes mellitus (GDM) and hypertensive disorders of pregnancy (HDP; gestational hypertension [gHTN] and preeclampsia). Objective To estimate disparities in GDM, gHTN and preeclampsia by sexual orientation. Methods We used data from the Nurses' Health Study II—a cohort of nurses across the US enrolled in 1989 ..read more
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Patterns of paternal medication dispensation around the time of conception
Paediatric and Perinatal Epidemiology
by Isobel McEwen, Krista F. Huybrechts, Loreen Straub, Sonia Hernández‐Díaz
2w ago
Abstract Background Past research on the safety of prenatal exposure to medications has focused on maternal use during gestation, with limited research into the potential effects of paternal use during the spermatogenic period preceding conception. Knowing the most common medications used by fathers around the time of conception can inform research priorities in this field. Objectives To identify the most common medications dispensed to fathers in the preconception period. Methods Within the MarketScan research database of commercially insured individuals in the United States from 2011 to 2020 ..read more
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Response: Multiple births as a mediator than a confounder in ART research
Paediatric and Perinatal Epidemiology
by Maria C. Magnus, Signe Opdahl
2w ago
Paediatric and Perinatal Epidemiology, EarlyView ..read more
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A selection of challenges in addressing selection bias
Paediatric and Perinatal Epidemiology
by Penelope P. Howards, Candice Y. Johnson
2w ago
Paediatric and Perinatal Epidemiology, EarlyView ..read more
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Pre‐existing conditions and pregnancy: A call to action for multidisciplinary, patient‐centred care
Paediatric and Perinatal Epidemiology
by Hilary K. Brown
1M ago
Paediatric and Perinatal Epidemiology, EarlyView ..read more
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Low‐dose aspirin, maternal cardiometabolic health, and offspring respiratory health 9 to 14 years after delivery: Findings from the EAGeR Follow‐up Study
Paediatric and Perinatal Epidemiology
by May Shaaban, Zachary D. Shepelak, Joseph B. Stanford, Robert M. Silver, Sunni L. Mumford, Enrique F. Schisterman, Stefanie N. Hinkle, Flory L. Nkoy, Lauren Theilen, Jessica Page, Jessica G. Woo, Benjamin H. Brown, Michael W. Varner, Karen C. Schliep
1M ago
Abstract Background Accumulating evidence shows that peri-conceptional and in-utero exposures have lifetime health impacts for mothers and their offspring. Objectives We conducted a Follow-Up Study of the Effects of Aspirin in Gestation and Reproduction (EAGeR) trial with two objectives. First, we determined if women who enrolled at the Utah site (N = 1001) of the EAGeR trial (2007–2011, N = 1228) could successfully be contacted and agree to complete an online questionnaire on their reproductive, cardio-metabolic, and offspring respiratory health 9–14 years after original enrollment. Second, w ..read more
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ICD‐10 coding for placenta accreta spectrum: An opportunity for improvement
Paediatric and Perinatal Epidemiology
by Robert M. Silver, Brett D. Einerson
1M ago
Paediatric and Perinatal Epidemiology, EarlyView ..read more
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Issue Information
Paediatric and Perinatal Epidemiology
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1M ago
Paediatric and Perinatal Epidemiology, Volume 38, Issue 4, Page i-iii, May 2024 ..read more
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Risks of congenital malformations and neonatal intensive care unit admissions with gabapentin use in pregnancy: A cohort study and scoping review with meta‐analysis
Paediatric and Perinatal Epidemiology
by Brianne Desrochers, Alekhya Lavu, Eunice Valencia, Christine Vaccaro, Payam Peymani, Sherif Eltonsy
1M ago
Abstract Background The increasing and prevalent use of gabapentin among pregnant people highlights the necessity to assess its neonatal safety. Objectives This study aimed to investigate the foetal safety of gabapentin during pregnancy using a cohort study and scoping review with a meta-analysis of published evidence. Methods We conducted a population-based cohort study using the Manitoba health databases between 1995 and 2019. We examined the association between gabapentin use during pregnancy and the prevalence of major congenital malformations, cardiac and orofacial malformations, and neon ..read more
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