Antisense Molecules in Epilepsy—A Neuropharmacological Educational Review
International Journal of Epilepsy
by George Stephen, Jefry Winner, George Stephen, Jesiha, Ali, Mohammed, Kumar, Ashwin, Jose, Susanna
1M ago
International Journal of Epilepsy DOI: 10.1055/s-0044-1779694 Epilepsy is a common neurological disorder. Epilepsy has many therapeutic options, the popular one being antiseizure medications. A good proportion of patients always responds well to the existing treatment modalities. But some patients develop resistant epilepsy, and treating them can be challenging with the current treatment; such scenarios are encountered frequently in patients, especially those under treatment for long-term as well as specific syndromes and channelopathies. Resistant epilepsy warrants the need to develop newer t ..read more
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A Survey on Epilepsy and Work: Profiles and Challenges
International Journal of Epilepsy
by D'Souza, Carol, Mani, Jayanti, Shah, Urvashi, Ravat, Parthvi, Sapre, Antara, Sanwalka, Neha, Ravat, Sangeeta, Desai, Joy, Shah, Pravina
2M ago
International Journal of Epilepsy DOI: 10.1055/s-0044-1781424 Objective Epilepsy can have a chronic course in a subgroup of people and may impact the ability to study, marry or earn a living thereby increasing significantly the burden of the illness. For a person with epilepsy (PWE), beyond seizure control, being participative and productive in life is a crucial factor for a good quality of life. The aim of the study was to explore factors that help and/or hinder PWE find work / employment. Materials and Methods Data was collected via a self-reported structured questionnaire from PWE in the ag ..read more
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New Onset Encephalopathy with Toxic Triphasic Waves
International Journal of Epilepsy
by PC, Amrutha, Nambiar, Poornima Narayanan, KM, Navaf, Aslam, Sarfaraz, NC, Krishnadas, Pillai, Deep P, Sureshbabu, Sachin
2M ago
International Journal of Epilepsy DOI: 10.1055/s-0044-1779695 New onset encephalopathy can have various causes like stroke, trauma, seizures, infections, demyelination, neoplasms, autoimmune, degenerative, and toxic and metabolic etiologies. Triphasic waves in electroencephalogram (EEG) is usually a clue to an ongoing metabolic process. We report a case of a 69-year-old female with bipolar disorder who presented with altered sensorium for the last 2 days. Her metabolic parameters, imaging, and cerebrospinal fluid findings were normal. Her EEG findings in the clinical setting provided a diagnos ..read more
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Brivaracetam-Induced Behavioral Changes
International Journal of Epilepsy
by Kumar, Akanksha, Kumar, Kamlesh, Kumawat, Rohit, Dhankhar, Kailash
2M ago
International Journal of Epilepsy DOI: 10.1055/s-0044-1779696 Thieme Medical and Scientific Publishers Pvt. Ltd. A-12, 2nd Floor, Sector 2, Noida-201301 UP, India Article in Thieme eJournals: Table of contents  |  open access Full text ..read more
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The Clinical Efficacy and Safety of Acute Care Setting for Intravenous Levetiracetam (Focale) in Children
International Journal of Epilepsy
by Tiamkao, Siriporn, Ruangritkul, Preechaya, Chainirun, Nanthaphan, Hutthawanichakornkul, Tarnthip, Bungtong, Issara, Thongjankaew, Pinjutha, Mungmanitmongkol, Sineenard, Tiamkao, Somsak, Auvichayapat, Narong, Sawanyawisuth, Kittisak
7M ago
International Journal of Epilepsy DOI: 10.1055/s-0043-1774744 Background Status epilepticus (SE) is a serious neurological emergency with a high mortality rate. Although levetiracetam is an effective antiepileptic drug for managing SE, its excessive cost may limit its accessibility. Focale, a more affordable generic version, is currently available and is more than 50% less expensive than the original version. However, there is currently no study on the efficacy and safety of Focale in pediatric patients with SE. Objective This study aimed to investigate the efficacy and safety of the antiepile ..read more
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Reproductive Health of Women with Epilepsy in India: An Observational Study
International Journal of Epilepsy
by Kumar, Aadithya Narayan Sunil, Aghoram, Rajeswari, Keepanasseril, Aneesh, Nair, Pradeep P.
7M ago
International Journal of Epilepsy DOI: 10.1055/s-0043-1772709 Objectives Women with epilepsy (WWE) have special reproductive health needs. We compare menstrual disorders, obstetric outcomes, and patterns of contraceptive use among WWE in the reproductive age group to those without epilepsy. Methods Sixty WWE between the ages of 18 and 45 years were randomly selected from a hospital database, and 60 controls in the same age group were recruited from among their families or close contacts. A questionnaire adapted from the National Family Health Survey 5 (NFHS-5) was administered to collect data ..read more
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Awareness and Attitude among Nonmedical University Students on Epilepsy in Lebanon: A Cross-Sectional Study
International Journal of Epilepsy
by Berjaoui, Christin, Atrouni, Salim, Doumiati, Hassan, Mezher, Hayat, Sinno, Loubna, ElJarkass, Hania
9M ago
International Journal of Epilepsy DOI: 10.1055/s-0043-1771205 Background Several studies addressed the awareness and knowledge of epilepsy among students and teachers that indicated unfavorable levels of awareness, but none in Lebanon. Aim The aim of this study is to determine the level of awareness and attitude toward epilepsy among nonmedical university students. Methods A survey-based questionnaire was conducted among 1,000 nonmedical students. SPSS was used for data analysis. Results Participants claimed 78.5% having some knowledge about epilepsy (78.5%), with only 20.1% of the participant ..read more
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Knowledge, Risk Perception, and Reproductive Decision Making among Women with Epilepsy
International Journal of Epilepsy
by Srikanth, Pallerla, Vranda, Mysore Narasimha, Thomas, Priya Treesa, Raghvendra, Kenchaiah
1y ago
International Journal of Epilepsy DOI: 10.1055/s-0043-1768584 Introduction Epilepsy is a neurological disorder that causes neurobiological, cognitive, and psychosocial consequences. Such impairments lead to substantial social influence on women across their life cycle stages, mostly connected with stigma, the severity of illness, quality of life, and other psychosocial issues in adding to reproductive decision-making associated to risk perception. This study aimed to assess the knowledge, risk perception, and reproductive decision-making factors among women with epilepsy. Materials and Methods ..read more
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Self-Limited Epilepsy with Autonomic Seizures (SeLEAS): A Retrospective Case Series
International Journal of Epilepsy
by Anand, Aakanksha, Kumar, Ashna, Garg, Divyani, Kansal, Bhavya, Saluja, Simar, Sharma, Suvasini
1y ago
International Journal of Epilepsy DOI: 10.1055/s-0043-57246 Objective Self-Limited Epilepsy with Autonomic Seizures (SeLEAS), previously known by the eponymous Panayiotopoulos syndrome, is a benign focal epilepsy of the pediatric age group. It is characterized by nocturnal seizures with dominant autonomic features. Limited data from India exists on SeLEAS. We aimed to describe the clinical, demographic, and treatment-related features of SeLEAS. Methods In this descriptive retrospective cohort study, we reviewed record of children who met criteria for SeLEAS. Each patient's clinical, demographi ..read more
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Reassures Me There Are People Around Who Care about Me: Analyzing Meanings of Support for People with Epilepsy
International Journal of Epilepsy
by Walker, Christine, Peterson, Chris L.
1y ago
International Journal of Epilepsy DOI: 10.1055/s-0043-1764396 Aims The study aimed to examine the nature and outcomes of social support for the well-being and quality of life (QoL) of adults with epilepsy. Methods The Australian Epilepsy Longitudinal Survey's 5th Wave included the Medical Outcomes Study Modified Social Support Survey on four dimensions of social support and the QOLIE-31. Both numerical data and open-ended responses were analyzed quantitatively and qualitatively. A mixed method was used where quantitative analysis used t-tests, analysis of variance and block recursive regressio ..read more
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