Welcome to the next episode of the Personalized Medicine Podcast. In this episode, our host Aradhana sat down for a conversation with Dr Ali Aghebat Rafat, Scientist at Tilibit Nanosystems. Aradhana and Ali discussed DNA nanostructures, DNA self-assembly, barcoding, biochips and their potential applications in Personalized Medicine. Tune in to this episode to learn more about: ◦ Tilibit Nanosystems and their mission ◦ Application areas of DNA origami in diagnostics ◦ What is DNA Paint ◦ A day in a life of a start-up scientist ◦ Role of nucleic acid nanostructures in Personalized Medicine ◦ Th ..read more

Welcome to the next episode of the Personalized Medicine Podcast. In this episode, our host Aradhana talked to Martin Rabel, the Field Application Scientist at Precision Nanosystems, about nanoparticles, microfluidics, gene delivery in the context of personalized medicine. Tune in to this episode to learn more about: ◦ Precision Nanosystems and their mission ◦ Role of nanoparticles and microfluidics in Personalized Medicine ◦ Next-Gen microfluidics technologies ◦ Application of nanoparticles in pharmaceutical applications ◦ Challenges in developing RNA-based lipid nanoparticles ◦ Role of regu ..read more

In this episode we dive deep into the world of structural biology. We discuss the role of cryogenic electron microscopy in the development of precision medicines with the founder and CEO of Gandeeva Therapeutics, Dr. Sriram Subramaniam. Cryo-EM opened a new way to study drug-target interactions and is changing the way we develop new therapies. Tune into our interview with Sriram to learn more about: ◦ The founding story of Gandeeva Therapeutics ◦ The evolution of Cryo-EM technology ◦ Application of Cryo-EM in drug discovery ◦ Advantages of Cryo-EM over crystallography im mapping protein struc ..read more

In this next podcast episode we dive into a topic of personalized skincare. Our host Oleksandr is joined by the co-founders of Mitra Bio, Dr. Shakiba Kaveh and Dr. Cristiana Banila. Pharmaceutical and personal care companies have been trying to unlock personalized skincare for decades. Shakiba and Cristiana bring a special key to the table, and it is epigenetics. Tune in into our interview to learn more about: ◦ The founding story of Mitra Bio ◦ The role of genetic and epigenetic factors in skin health ◦ Cracking epigenetic code ◦ Role of reliable models in understanding skin diseases ◦ Skin ..read more

Welcome to the next episode of the Personalized Medicine Podcast. In this episode, we have talked about a variety of topics ranging from exploring space and microgravity for applications in biotechnology and physical science to developing pathogen detection systems. Our guest today is Dr. Daniela Bezdan, the Chief Scientific Officer of Yuri Gravity and co-founder of Poppy. Daniela is also the co-chair at several space-associated organizations such as ISSOP (International Space Standards Operation Procedure) and NASA GeneLabs that foster international cooperation, and support educational citiz ..read more

Welcome to the next episode of the Personalized Medicine Podcast. On this podcast we have talked extensively about antibody, vaccine and CAR-T cell based approaches to treat cancer. Today we will be talking about a new approach in oncology that is based on invariant Natural Killer T Cells, or iNKTs. Our guest today is Dr. Jennifer Buell, the founder, CEO and President of MiNK Therapeutics and the former President and COO of Agenus. Jennifer has over 25 years of experience in the biopharmaceutical space, having held multiple leadership positions at biotech companies. In her tenure at Agenus, s ..read more

In this episode we dive deep again into the topic of protein degradation and how it can be leveraged to treat neurodegenerative diseases. Our guest today is Dr. Beth Hoffman, the founder, CEO and President to Origami Therapeutics. Beth's career is a showcase of remarkable success in the biotech industry. She spent almost 25 years working in CNS drug discovery and was involved in the development of over 30 therapeutic molecules. Most notably she led the discovery and development of a few first-in-class blockbuster drugs for cystic fibrosis at Vertex Pharmaceuticals. Her most recent venture, Ori ..read more

Thank you very much for tuning into this special episode of the Personalized Medicine Podcast. Some of you might know that our founder and host Oleksandr (a.k.a. Sasha) is Ukrainian. In this difficult moment for his country, Sasha shares his thoughts on current situation in Ukraine and explains how anyone in the world can help and support people of Ukraine and its scientific community. Out team has prepared a list of trusted organizations and charitable foundations supporting Ukraine at the moment: Support Ukrainian military (Official Bank Account of Ukrainian Ministry of Defense): https://b ..read more

In this episode we are returning to a very exciting topic of immunooncology and we will talk in detail about novel approaches to treat cancer, based on CAR-T cell technology. Please welcome Dr. Eric von Hofe, the Senior Advisor and former President of Affyimmune Therapeutics. Eric’s story is a showcase of a remarkable career in the biotech industry. Eric studied Biology at UC Berkeley and received his PhD from the University of Southern California. HEric continued his career in cancer research doing two PostDocs at ETH Zurich and Harvard and then taking a position of Assistant Professor at th ..read more

Welcome to the next episode of the Personalized Medicine Podcast. On this show we typically talk about science and technology driving the progress in personalized medicine. But the policy side of things and patient access are equally important. We are happy to welcome on our podcast Christopher Wells, the Vice President of Public Affairs at the Personalized Medicine Coalition. Chris has recently published an article in STAT in which he eloquently described why we cannot narrow down personalized medicine just to cancer and need to look at it through a larger lens. And this is what we have disc ..read more