Circ_0000620 acts as an oncogenic factor in gastric cancer through regulating MMP2 expression via sponging miR-671-5p
Journal of Biological Research-Thessaloniki
by Junyu Ren, Guoqing Pan, Jun Yang, Ning Xu, Qiong Zhang and Wenliang Li
2y ago
Gastric cancer (GC) is one of the most common cancers in the digestive system. Circular RNAs (circRNAs) have been found to function as important regulators in the pathogenesis of GC. This study focused on the ..read more
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Peroxiredoxin-6 regulates p38-mediated epithelial–mesenchymal transition in HCT116 colon cancer cells
Journal of Biological Research-Thessaloniki
by Unbin Chae, Bokyung Kim, HanSeop Kim, Young-Ho Park, Seung Hwan Lee, Sun-Uk Kim and Dong-Seok Lee
2y ago
Peroxiredoxins (Prxs) are antioxidant enzymes that protect cells from oxidative stress induced by several factors. They regulate several signaling pathways, such as metabolism, immune response, and intracellul ..read more
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Nesfatin-1 protects H9c2 cardiomyocytes against cobalt chloride-induced hypoxic injury by modulating the MAPK and Notch1 signaling pathways
Journal of Biological Research-Thessaloniki
by Mingchen Li, Kai Li and Yuan Ren
2y ago
This study aimed to explore the effect of nesfatin-1 on cobalt chloride (CoCl2)-induced hypoxic injury in cardiomyocyte H9c2 cells ..read more
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LncRNA FBXL19-AS1 promotes proliferation and metastasis of cervical cancer through upregulating COL1A1 as a sponge of miR-193a-5p
Journal of Biological Research-Thessaloniki
by Xiaoyong Huang, Haiyan Shi, Xinghai Shi and Xuemei Jiang
2y ago
Cervical cancer (CC) is one of the most common and malignant tumors in women. In this study, we aim to explore the role and mechanism of F-box and leucine rich repeat protein 19 antisense RNA 1 (FBXL19-AS1), a ..read more
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CircCNIH4 inhibits gastric cancer progression via regulating DKK2 and FRZB expression and Wnt/β-catenin pathway
Journal of Biological Research-Thessaloniki
by Qi Shi, Chuanwen Zhou, Rui Xie, Miaomiao Li, Peng Shen, Yining Lu and Shijie Ma
2y ago
Circular RNAs (circRNAs) have been reported to play an important role in tumor progression in various cancer types, including gastric cancer. The aim of this study was to investigate the role of circCNIH4 (hsa ..read more
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Predicted antiviral drugs Darunavir, Amprenavir, Rimantadine and Saquinavir can potentially bind to neutralize SARS-CoV-2 conserved proteins
Journal of Biological Research-Thessaloniki
by Umesh C. Halder
2y ago
Novel Coronavirus disease 2019 or COVID-19 has become a threat to human society due to fast spreading and increasing mortality. It uses vertebrate hosts and presently deploys humans. Life cycle and pathogenici ..read more
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Callose: a multifunctional (1, 3)-β–d-glucan involved in morphogenesis and function of angiosperm stomata
Journal of Biological Research-Thessaloniki
by Panagiotis Apostolakos, Eleni Giannoutsou and Basil Galatis
2y ago
Although the cellulose microfibril organization in guard cell (GC) walls play a crucial role in the mechanism of the stomatal function, recent work showed that matrix cell wall materials are also involved. Esp ..read more
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PTD-mediated delivery of α-globin chain into Κ-562 erythroleukemia cells and α-thalassemic (HBH) patients’ RBCs ex vivo in the frame of Protein Replacement Therapy
Journal of Biological Research-Thessaloniki
by Androulla N. Miliotou, Dionysia Papagiannopoulou, Efthymia Vlachaki, Martina Samiotaki, Dimitra Laspa, Stamatia Theodoridou, Asterios S. Tsiftsoglou and Lefkothea C. Papadopoulou
3y ago
α-Thalassemia, a congenital hemoglobinopathy, is characterized by deficiency and/or reduced levels of α-globin chains in serious forms of α-thalassemia (HbH disease/Hb Bart’s). This research work deals with a ..read more
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Relationship between the structure and function of the transcriptional regulator E2A
Journal of Biological Research-Thessaloniki
by Jia-Jie Liang, Hu Peng, Jiao-Jiao Wang, Xiao-Hui Liu, Lan Ma, Yi-Ran Ni, Huai-Jie Yang, Yan-Qiong Zhang, Wen-Bing Ai and Jiang-Feng Wu
3y ago
E proteins are transcriptional regulators that regulate many developmental processes in animals and lymphocytosis and leukemia in Homo sapiens. In particular, E2A, a member of the E protein family, plays a major ..read more
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Sevoflurane inhibits malignant progression of colorectal cancer via hsa_circ_0000231-mediated miR-622
Journal of Biological Research-Thessaloniki
by Jingpeng Wang, Shuyuan Li, Gaofeng Zhang and Huihua Han
3y ago
Sevoflurane (Sev), a commonly used volatile anesthetic, has been reported to inhibit the process of colorectal cancer (CRC). Circular RNAs (circRNAs) are revealed to participate in the pathogenesis of CRC. Thi ..read more
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