Establishment of primary prostate epithelial and tumorigenic cell lines using a non-viral immortalization approach
Biological Research
by Simon Lange, Anna Kuntze, Neele Wüstmann, Theresa Reckers, Verena Humberg, Wilhelm G. Dirks, Sebastian Huss, Julia Vieler, Andres Jan Schrader, Martin Bögemann, Katrin Schlack and Christof Bernemann
5d ago
Research on prostate cancer is mostly performed using cell lines derived from metastatic disease, not reflecting stages of tumor initiation or early progression. Establishment of cancer cell lines derived from ..read more
Visit website
General regulatory factors exert differential effects on nucleosome sliding activity of the ISW1a complex
Biological Research
by Andrea Oyarzún-Cisterna, Cristián Gidi, Fernanda Raiqueo, Roberto Amigo, Camila Rivas, Marcela Torrejón and José L. Gutiérrez
5d ago
Chromatin dynamics is deeply involved in processes that require access to DNA, such as transcriptional regulation. Among the factors involved in chromatin dynamics at gene regulatory regions are general regula ..read more
Visit website
The effect of diabetes mellitus on differentiation of mesenchymal stem cells into insulin-producing cells
Biological Research
by Omar I. Badr, Mohamed M. Kamal, Shohda A. El-Maraghy and Heba R. Ghaiad
5d ago
Diabetes mellitus (DM) is a global epidemic with increasing incidences. DM is a metabolic disease associated with chronic hyperglycemia. Aside from conventional treatments, there is no clinically approved cure ..read more
Visit website
Control of astrocytic Ca2+ signaling by nitric oxide-dependent S-nitrosylation of Ca2+ homeostasis modulator 1 channels
Biological Research
by Mariela Puebla, Manuel F. Muñoz, Mauricio A. Lillo, Jorge E. Contreras and Xavier F. Figueroa
1w ago
Astrocytes Ca2+ signaling play a central role in the modulation of neuronal function. Activation of metabotropic glutamate receptors (mGluR) by glutamate released during an increase in synaptic activity triggers ..read more
Visit website
Increased levels and activation of the IL-17 receptor in microglia contribute to enhanced neuroinflammation in cerebellum of hyperammonemic rats
Biological Research
by Yaiza M. Arenas, Adrià López-Gramaje, Carmina Montoliu, Marta Llansola and Vicente Felipo
1w ago
Patients with liver cirrhosis may show minimal hepatic encephalopathy (MHE) with mild cognitive impairment and motor incoordination. Rats with chronic hyperammonemia reproduce these alterations. Motor incoordi ..read more
Visit website
Identification and expression analysis of two steamer-like retrotransposons in the Chilean blue mussel (Mytilus chilensis)
Biological Research
by Gloria Arriagada, Johan Quezada, Nicolas Merino-Veliz, Fernando Avilés, Diana Tapia-Cammas, Jorge Gomez, Daniela Curotto, Juan A. Valdes, Pablo A. Oyarzún, Cristian Gallardo-Escárate, Michael J. Metzger and Marco Alvarez
2w ago
Disseminated neoplasia (DN) is a proliferative cell disorder of the circulatory system of bivalve mollusks. The disease is transmitted between individuals and can also be induced by external chemical agents su ..read more
Visit website
Noncoding RNAs in skeletal development and disorders
Biological Research
by Qing Yao, Tailin He, Jian-You Liao, Rongdong Liao, Xiaohao Wu, Lijun Lin and Guozhi Xiao
2w ago
Protein-encoding genes only constitute less than 2% of total human genomic sequences, and 98% of genetic information was previously referred to as “junk DNA”. Meanwhile, non-coding RNAs (ncRNAs) consist of app ..read more
Visit website
Galectins in epithelial-mesenchymal transition: roles and mechanisms contributing to tissue repair, fibrosis and cancer metastasis
Biological Research
by Elisa Perez-Moreno, Claudia Oyanadel, Adely de la Peña, Ronny Hernández, Francisca Pérez-Molina, Claudia Metz, Alfonso González and Andrea Soza
1M ago
Galectins are soluble glycan-binding proteins that interact with a wide range of glycoproteins and glycolipids and modulate a broad spectrum of physiological and pathological processes. The expression and subc ..read more
Visit website
Cx43 hemichannels and panx1 channels contribute to ethanol-induced astrocyte dysfunction and damage
Biological Research
by Gonzalo I. Gómez, Tanhia F. Alvear, Daniela A. Roa, Arantza Farias-Pasten, Sergio A. Vergara, Luis A. Mellado, Claudio J. Martinez-Araya, Juan Prieto-Villalobos, Claudia García-Rodríguez, Natalia Sánchez, Juan C. Sáez, Fernando C. Ortíz and Juan A. Orellana
1M ago
Alcohol, a widely abused drug, significantly diminishes life quality, causing chronic diseases and psychiatric issues, with severe health, societal, and economic repercussions. Previously, we demonstrated that ..read more
Visit website
The long-chain flavodoxin FldX1 improves the biodegradation of 4-hydroxyphenylacetate and 3-hydroxyphenylacetate and counteracts the oxidative stress associated to aromatic catabolism in Paraburkholderia xenovorans
Biological Research
by Laura Rodríguez-Castro, Roberto E. Durán, Valentina Méndez, Flavia Dorochesi, Daniela Zühlke, Katharina Riedel and Michael Seeger
1M ago
Bacterial aromatic degradation may cause oxidative stress. The long-chain flavodoxin FldX1 of Paraburkholderia xenovorans LB400 counteracts reactive oxygen species (ROS). The aim of this study was to evaluate the ..read more
Visit website

Follow Biological Research on FeedSpot

Continue with Google
Continue with Apple
OR