Polar lipids modify Alzheimer’s Disease pathology by reducing astrocyte pro-inflammatory signaling through platelet-activating factor receptor (PTAFR) modulation
Lipids in Health and Disease
by Sakshi Hans, Janelle E. Stanton, Ann Katrin Sauer, Katie Shiels, Sushanta Kumar Saha, Ronan Lordan, Alexandros Tsoupras, Ioannis Zabetakis and Andreas M. Grabrucker
2d ago
Pro-inflammatory processes triggered by the accumulation of extracellular amyloid beta (Aβ) peptides are a well-described pathology in Alzheimer's disease (AD). Activated astrocytes surrounding Aβ plaques cont ..read more
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Dose-response associations of triglyceride to high-density lipoprotein cholesterol ratio and triglyceride–glucose index with arterial stiffness risk
Lipids in Health and Disease
by Wenkai Zhang, Weifeng Huo, Huifang Hu, Tianze Li, Lijun Yuan, Jinli Zhang, Yifei Feng, Yuying Wu, Xueru Fu, Yamin Ke, Mengmeng Wang, Longkang Wang, Yaobing Chen, Yajuan Gao, Xi Li, Liang Sun…
2d ago
The triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio and triglyceride-glucose (TyG) index are novel indexes for insulin resistance (IR). We aimed to evaluate associations of TG/HDL-C and T ..read more
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Is cholesterol both the lock and key to abnormal transmembrane signals in Autism Spectrum Disorder?
Lipids in Health and Disease
by Clifford Lingwood
2d ago
Disturbances in cholesterol homeostasis have been associated with ASD. Lipid rafts are central in many transmembrane signaling pathways (including mTOR) and changes in raft cholesterol content affect their ord ..read more
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L-shaped association between lean body mass to visceral fat mass ratio with hyperuricemia: a cross-sectional study
Lipids in Health and Disease
by Longti Li, Ya Shao, Huiqin Zhong, Yu Wang, Rong Zhang, Boxiong Gong and Xiaoxv Yin
2d ago
Insufficient attention has been given to examining the correlation between body composition and hyperuricemia, leading to inconsistent findings. The primary objective of this research is to explore the associa ..read more
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Can essential fatty acids (EFAs) prevent and ameliorate post-COVID-19 long haul manifestations?
Lipids in Health and Disease
by Undurti N. Das
2d ago
It is hypothesized that COVID-19, post-COVID and post-mRNA COVID-19 (and other related) vaccine manifestations including “long haul syndrome” are due to deficiency of essential fatty acids (EFAs) and dysregula ..read more
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Identification and validation of biomarkers related to lipid metabolism in osteoarthritis based on machine learning algorithms
Lipids in Health and Disease
by Hang Li, Yubao Cui, Jian Wang, Wei Zhang, Yuhao Chen and Jijun Zhao
5d ago
Osteoarthritis and lipid metabolism are strongly associated, although the precise targets and regulatory mechanisms are unknown ..read more
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Blood lipids mediate the effects of gut microbiome on endometriosis: a mendelian randomization study
Lipids in Health and Disease
by Chang Su, Su Wan, Jin Ding, Guantai Ni and Huafeng Ding
5d ago
There is evidence for an association between the gut microbiome and endometriosis. However, their causal relationship and the mediating role of lipid metabolism remain unclear ..read more
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Effect of oesophagectomy on lipid profiles in patients with oesophageal cancer combined with hyperlipidaemia: a retrospective study
Lipids in Health and Disease
by Jingrong Yang, Yaxin Li, Jialei Huang, Jiabin Lai, Xiangrui Chen, Wenxuan Xia and Yu Wang
1w ago
Surgery is widely regarded as a pivotal therapeutic approach for treating oesophageal cancer, and clinical observations have revealed that many oesophageal cancer patients also present with concomitant hyperli ..read more
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Triglyceride-glucose index predicts postoperative delirium in elderly patients with type 2 diabetes mellitus: a retrospective cohort study
Lipids in Health and Disease
by Miao Sun, Min Liu, Faqiang Zhang, Lijuan Sang, Yuxiang Song, Peng Li, Siyuan Liu, Huikai Yang, Libin Ma, Jiangbei Cao, Weidong Mi and Yulong Ma
1w ago
Postoperative delirium (POD) is more prevalent among elderly patients with type 2 diabetes mellitus (T2DM). Insulin resistance (IR) can be assessed using the triglyceride-glucose (TyG) index, a novel biomarker ..read more
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The impact of lipidome on breast cancer: a Mendelian randomization study
Lipids in Health and Disease
by Yuchen Cao, Meichen Ai and Chunjun Liu
1w ago
This study aims to investigate the association between specific lipidomes and the risk of breast cancer (BC) using the Two-Sample Mendelian Randomization (TSMR) approach and Bayesian Model Averaging Mendelian ..read more
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