The New England Journal of Medicine : Allergy/Immunology articles
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The allergy and immunology hub contains articles on allergies, monoclonal antibodies, and autoimmune disease. The New England Journal of Medicine (NEJM) is a weekly general medical journal that publishes new medical research and review articles and editorial opinions on a wide variety of topics of importance to a biomedical science and clinical practice.
The New England Journal of Medicine : Allergy/Immunology articles
2y ago
Asthma affects more than 300 million persons worldwide, and its prevalence is increasing. Severe asthma affects approximately 5 to 10% of persons with asthma. Patients with severe asthma have poor disease control and frequent exacerbations in spite of treatment with high-dose inhaled ..read more
The New England Journal of Medicine : Allergy/Immunology articles
2y ago
Currently available biologic therapies targeting IgE, interleukin-4 and -13, and interleukin-5 are effective in treating moderate-to-severe type 2 asthma. However, many patients with type 2 or non–type 2 asthma continue to have symptoms, exacerbations, and reduced lung function. Therefore, new ..read more
The New England Journal of Medicine : Allergy/Immunology articles
2y ago
Basic science has enriched our understanding of the pathophysiology of severe asthma. Clinical translation of these discoveries has resulted in biologic therapies that target key components of asthma-related disease pathways. For example, identification and validation of biomarkers such as elevated ..read more
The New England Journal of Medicine : Allergy/Immunology articles
2y ago
Autoimmune hemolytic anemia (AIHA) is defined as increased destruction of red cells through autoimmune mechanisms, usually mediated by autoantibodies against erythrocyte surface antigens. During the past decade, important new findings have emerged regarding the cause, pathogenesis, diagnosis, and ..read more
The New England Journal of Medicine : Allergy/Immunology articles
2y ago
Crohn’s disease and ulcerative colitis, together referred to as inflammatory bowel disease (IBD), are chronic systemic inflammatory disorders. These conditions target primarily the gastrointestinal tract but can affect many organ systems through extraintestinal manifestations (e.g. peripheral and ..read more
The New England Journal of Medicine : Allergy/Immunology articles
2y ago
To the Editor: Since the U.S. measles immunization program began in 1963, death from vaccine-associated measles is extremely rare, and endemic measles has nearly been eliminated. Vaccine reactions after administration of the measles–mumps–rubella (MMR) vaccine are generally mild and may include ..read more
The New England Journal of Medicine : Allergy/Immunology articles
2y ago
Sarcoidosis is an inflammatory, multisystemic disease of unknown cause with a wide range of clinical manifestations. The disorder can affect virtually any organ in the body — predominantly the lungs, lymphatic system, skin, or eyes or a combination of these sites — and is characterized by the ..read more
The New England Journal of Medicine : Allergy/Immunology articles
2y ago
The mother clutches her daughter as the nebulized albuterol permeates the young girl’s airways. My eyes dart between the monitor and the child’s small, dark-skinned chest as it heaves up and down at an alarming rate. I smile reassuringly, but the mother’s eyes begin to well with tears as she ..read more