Background: Indian subcontinent has high burden of patients suffering from respiratory allergy associated with food sensitization. Immune response is different in skin and blood for allergen sensitization. Skin Prick Test (SPT) and Specific IgE (s IgE) allergen positivity is an evidence of sensitization. Both these tests (SPT & sIgE) are often used interchangeably in clinical practice of allergic disorders. In our study the concordance relevance of various tests SPT, sIgE, Total IgE, Absolute Eosinophil Count (AEC) & Serum Cortisol was investigated in 75 patients of respiratory allergy ..read more

Drugs known as Selective Serotonin Reuptake Inhibitors (SSRI) are amongst the most commonly described psychotropic drugs. These are used in the treatment of a multitude of Psychiatric and non-psychiatric conditions and are also being explored as potential immunosuppressants/immunomodulators [1 ..read more

There seems to be no unanimity of opinion as to the mode of transmission of allergic disease. According to some, allergy is transmitted as a simple Mendelian dominant. In direct contrast, others maintain that the findings favor a recessive mechanism. Further- more, others suggest that the condition is inherited as a “partial dominant” disorder. An additional analysis of family studies as well as data already published, failed to support either the simple dominant or recessive theory. The dominant theory does not explain why in more than half of the pedigrees both parents are normal ..read more

This survey evaluated the impact of food allergy on the allergic person's travel decision, trip organization and stay abroad. Hundred and two persons have participated. Results show that food allergy prevents 14% of respondents from travelling. Of the 81 travellers, 49% gets anxiety and 46% fear from food allergy. Difficulties related to food intake at restaurants were expressed by 67% of travellers. It is shown that allergic travellers adopt preventive behaviours and avoidance attitudes of allergenic products such as carrying their own food, reading labels, avoiding consumption of local foods ..read more

Asthma is common chronic inflammatory disease of the airways characterised by variable and attacks of cough and breathlesness, usually precipitated by an enviromental trigger (air pollution, smoke, etc). The prevalence and severity for allergic asthma have increased markedly in the last several decades. Dysregulated expression patterns of pro- and anti inflammatory mechanisms are thought to be responsible for the development of chronic inflammation. The risk of developing asthma has a strong genetic component, with estimated heritability ranging from 35 to 85%. The mechanism of action of Omali ..read more

Asthma is a well known and high impact global health problem [1]. It shares, along with other prevalent entities, a number of not insignificant difficulties in the delivery of health care needs for it's control [2]. From a clinical Point of view, the use of inhaled steroid medications (Clinical Efficacy measured as: No. of asthmatics patients controlled /No. of asthmatics patients treated) have proven their worth and are the mainstay of treatment in many Published Guidelines about asthma; and deservedly so. However, from a public health point of view, the clinical effectiveness of such strateg ..read more

Background: Food allergens appear to play a role in the etiology and deteriorating of atopy in some patients, little is known about hypersensitivity to some common food additives in these patients. The purpose of this study was to identify probable sensitization to saffron, sumac and barberry in patients with atopy ..read more

Importance: Allergic rhinitis affects about 20% of the population worldwide. Available pharmacological treatments are helpful but not ideal in providing relief; safer and more effective treatments are needed. Objective: To evaluate the efficacy and safety of Nasapaque nasal solution vs placebo for relief or prophylactic treatment of seasonal allergic rhinitis ..read more

Mini review article deals with the most studied group of chemical compounds – polyphenols – predominantly flavonoids in relation to their allergic immune response. There is clarified and discussed their mechanism of action as well. We emphasized on the strongest inhibitors of allergic reactions - luteolin, fisetin and apigenin, but in the second part the currently studied flavonoids have been summarized as well ..read more

Case Presentation: A 42-year-old woman, with no atopic history, has experienced two anaphylactic reactions after consuming yuzu. Skin prick tests (SPTs) were performed with juice, peel and pulp of commercially available lemon, orange, grapefruit, tangerine and yuzu, 2 cultivars of Citrus junos, 2 cultivars of Citrus reticulata, one Citrus ichangensis and food consumed during the culprit meal ..read more