Supplementary File 1 (ZIP, 198 KiB) 12 pages, 3156 KiB   ; Brassicaceae) and Other Cultivars in Korea polymorphism. The FVB/N strain without the R2140C mutation resists ADR nephropathy. Meanwhile, a detailed analysis of the progression of The Adriamycin (ADR) nephropathy model, which induces podocyte injury, is limited to certain mouse strains due to genetic susceptibilities, such as the ) is a dosage-sensitive gene that causes autistic phenotypes when deleted or duplicated. Observations from clinical cases and animal models also suggest that changes of - 05 Apr 2024 To date, genomic and ..read more

Gene Family Variants Are Associated with Response to Apremilast Treatment in Psoriasis Developmental Changes in Genome Replication Progression in Pluripotent versus Differentiated Human Cells (Burm. f.) Nees and Their Role in Andrographolide Production ..read more

Optimization of HIV Sequencing Method Using Vela Sentosa Library on Miseq Ilumina Platform Gene Family Variants Are Associated with Response to Apremilast Treatment in Psoriasis ..read more

17 pages, 2208 KiB   8 pages, 210 KiB   (4), 431; https://doi.org/10.3390/genes15040431 (registering DOI) - 29 Mar 2024 Many investigations have evaluated the expression of noncoding RNAs (ncRNAs) as well as their related molecular functions and biological machineries in individuals with alcohol dependence. Alcohol dependence may be one of the most prevailing psychological disorders globally, and its pathogenesis is intricate and - 28 Mar 2024 Satellite DNA (satDNA) consists of sequences of DNA that form tandem repetitions across the genome, and it is notorious for its diversity ..read more

Human Leukocyte Antigen Markers for Distinguishing Pustular Psoriasis and Adult-Onset Immunodeficiency with Pustular Reaction ..read more

9 pages, 241 KiB   New Genetic Markers of Skin T-Cell Lymphoma Treatment = 0.02, specificity 0.965). The AA genotype in the CD147 polymorphism was 12 times more frequent in patients who underwent systemic therapy of CTCL compared to those not treated with this therapy ( = 0.009, specificity 0.976). The same genotype was also associated with radiotherapy—it was observed 14 times more frequently in patients treated with radiotherapy ( = 0.009, specificity 0.959). In patients treated with interferon α therapy, the AA genotype was observed to be 5.85 times more frequent compared to the patien ..read more

Genetic Regulation of Animal Reproduction Editors: Wajid Zaman, Hakim Manghwar ..read more

11 pages, 1633 KiB   18 pages, 6469 KiB   gene (c.596 A>C; p.Gln199Pro) through whole exome sequencing in a POI patient, a Disruption of meiosis and DNA repair genes is associated with female fertility disorders like premature ovarian insufficiency (POI). In this study, we identified a homozygous missense variant in the , etc.) exhibited heightened expression. A weighted gene co-expression network analysis (WGCNA) identified regulatory genes ( variant with POI, we used CRISPR/Cas9 to create a knock-in mouse model harbouring the equivalent of the human gene showed five potential re ..read more

21 pages, 1122 KiB   Variants Cause Atrioventricular Node Dysfunction and Arrhythmogenic Changes in Cardiac Electrophysiology and Intracellular Calcium Handling in Zebrafish Lignin is complex, three-dimensional biopolymer existing in plant cell wall. Lignin biosynthesis is increasingly highlighted because it is closely related to the wide applications in agriculture and industry productions, including in pulping process, forage digestibility, bio-fuel, and carbon sequestration. The functions of lignin Genetic Risk Factors and Clinical Outcomes in Childhood Eye Cancers: A Review Reveals It ..read more

21 pages, 1122 KiB   Variants Cause Atrioventricular Node Dysfunction and Arrhythmogenic Changes in Cardiac Electrophysiology and Intracellular Calcium Handling in Zebrafish Lignin is complex, three-dimensional biopolymer existing in plant cell wall. Lignin biosynthesis is increasingly highlighted because it is closely related to the wide applications in agriculture and industry productions, including in pulping process, forage digestibility, bio-fuel, and carbon sequestration. The functions of lignin Genetic Risk Factors and Clinical Outcomes in Childhood Eye Cancers: A Review Reveals It ..read more