
MDPI » Genes
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MDPI » Genes
4d ago
Supplementary File 1 (ZIP, 2209 KiB) Neuromolecular Basis of Impaired Conditioned Taste Aversion Acquisition in Valproate-Induced Rat Model of Autism Spectrum Disorder Identification of the SbDUF966 Gene Family in Sorghum and Investigation of It Role in Response to Abiotic Stresses (This article belongs to the Section CNV genotype frequencies across the three breeds, with the highest proportion of deletions observed in STHS (98.44%) and CKS (90.57%), while HS exhibited a higher frequency of duplications (14.06%). No significant associations were observed between , which can be targeted to enha ..read more
MDPI » Genes
2w ago
Long Noncoding RNAs Responding to Ethanol Stress in Yeast Seem Associated with Protein Synthesis and Membrane Integrity ..read more
MDPI » Genes
2w ago
11 pages, 466 KiB 14 pages, 1803 KiB Genetic factors have been hypothesized to contribute to the heterogeneity in the response to infectious diseases (IDs). The classical twin design provides a powerful tool to estimate the role of genetic contributions to variation in infection outcomes. With this design, the impact of Introduction: The variants rs10517086 and rs1534422 are predictive of type 1 diabetes mellitus (T1DM) development and poor residual β cell function within the first year of diagnosis. However, the mechanism by which risk is conferred is unknown. We explored the im ..read more
MDPI » Genes
3w ago
Study on Genotypes and Phenotypes of Neurodegenerative Diseases Editors: Katarzyna Piórkowska, Katarzyna Ropka-Molik ..read more
MDPI » Genes
3w ago
Genome Sequencing Reveals the Potential of sp. Strain UNJFSC003 for Hydrocarbon Bioremediation ..read more
MDPI » Genes
3w ago
Supplementary File 1 (ZIP, 1556 KiB) 11 pages, 1252 KiB Unravelling the Relationship Between Height, Lean Mass, Alzheimer’s Disease and Cognition Through Mendelian Randomization - 21 Jan 2025 Background: Genetic evidence from Mendelian randomization (MR) analyses suggests that higher lean mass causally protects against Alzheimer’s disease (AD) and enhances cognitive function. However, the potential confounding role of height, which shares genetic etiology with lean mass, has not been fully examined. Methods: Background: Genetic evidence from Mendelian randomization (MR) analyses suggest ..read more
MDPI » Genes
2M ago
15 pages, 3634 KiB Neutral Genetic Diversity in Mixed Mating Systems ), a perennial herb of the Araceae family, is indigenous to Xinxian County, Henan Province, China, and is regarded as a premium variety among similar medicinal materials. However, the lack of comprehensive genetic information on Xi Junecry germplasm resources has constrained the cultivation and identification of high-quality varieties. : In this study, six chloroplast genomes of Xi Junecry were assembled and annotated using high-throughput sequencing. Subsequently, comparative analyses were conducted, and a phylogeneti ..read more
MDPI » Genes
2M ago
Tracing ALS Degeneration: Insights from Spinal Cord and Cortex Transcriptomes ..read more
MDPI » Genes
2M ago
Supplementary File 1 (ZIP, 182 KiB) 12 pages, 4934 KiB Comparative and Adaptive Analyses of the Complete Chloroplast Genome Diversity in Background/Objectives: Mesenchymal stem cells (MSCs) possess the remarkable ability to differentiate into various cell types, including osteoblasts. Understanding the molecular mechanisms governing MSC osteogenic differentiation is crucial for advancing clinical applications and our comprehension of complex disease processes. However, the key biological molecules Background/Objectives: Mesenchymal stem cells (MSCs) possess the remarkable ability to dif ..read more
MDPI » Genes
2M ago
18 pages, 4639 KiB 15 pages, 1577 KiB is the pathogenic anaerobe most commonly isolated from intra-abdominal infections, abscesses, and blood. Despite its clinical importance, research on its pan-genome-scale evolution is still limited. Methods: Herein, we analyzed the pan-genome architecture of 374 can provide fundamental insights into its . Additionally, a considerable depletion of recombination in genes with Fst values > 0.99 was noted, suggesting that the highest Fst genes with little recombination are the basis for differentiation between divisions. Conclusions: Overall ..read more