First: We bring you new developments on the hunt for an assassin who took out one of the most powerful business leaders in America. The search is accompanied by growing law enforcement concern that more than 24 hours after the Manhattan murder, the suspect could be anywhere.  Plus: Refusing to retreat, Donald Trump's embattled Pentagon pick says he has the full support of the president-elect. Nevertheless, some Republican senators remain skeptical, including one who's dropping some not-so-subtle, not-so-positive hints about him.  And: Dana talks to a powerful Republican committe ..read more

As today's show begins we're still learning about the shocking murder of United Health Care CEO Brian Thompson this morning outside the Hilton hotel in midtown Manhattan. Our coverage begins with a live report from CNN correspondent Brynn Gingras.  Learn more about your ad choices. Visit podcastchoices.com/adchoices ..read more

First: South Korea, a key US ally, is reeling after its democratically elected president declared martial law. CNN is live on the ground with the latest.  Plus: Booze, unwanted advances and an Islamophobic chant are some only some of the new allegations facing Donald Trump's pick to run the Pentagon.  And: Top strategists from both parties will debate the question many are grappling with in the political environment: What's the moral high ground?    Learn more about your ad choices. Visit podcastchoices.com/adchoices ..read more

First: We bring you the mixed reaction from last night's surprise White House announcement that Joe Biden issued a "full and unconditional pardon" for his son, Hunter, whom the president says was unfairly targeted.  Plus: Senate Republicans stand in the way of Kash Patel becoming the FBI director or confirm the man who promises to dismantle the law enforcement agency and rebuild it exactly how Donald Trump wants it.  And: Democrats are looking for a new DNC chair. Dana talks to someone who thinks he's best equipped for the job of guiding the party out of the wilderness.  Learn m ..read more

First: Bombshell pick. President-elect Trump chooses a new FBI director. Controversial loyalist Kash Patel. Can he get confirmed? What will he do if he is? My panel of experts will break it all down. And: The Elon effect. Elon Musk celebrates Thanksgiving at Mar-a-Lago as the Tesla CEO gears up for his new role. How will he shape the future of government? Tesla and SpaceX investor Cathie Wood will join me live. Plus: Democrats search for a path forward. Who will they choose to lead their party in the new Trump era? I'll ask Wisconsin Democratic Party Chairman Ben Wikler.  Learn more about ..read more

First: Donald Trump spent Thanksgiving night with loved ones Melania, Barron and ... Elon Musk? We look at their relationship and preview Musk's trip to Washington next week to meet with Republican lawmakers.  Plus: A controversy over raw milk as bird flu is found in another batch of it in California. Experts say unpasteurized milk is a vector for infectious diseases. But Robert F Kennedy Jr. wants more Americans drinking it and may soon be in a position to promote it.  And: What went wrong? A top Democratic pollster joins the show with some tough truths for his party about why ..read more

First: Loyalty test. From Matt Gaetz to RFK Jr., Trump's choices shocked Washington. The Republicans fall in line. Plus: New details on RFK Jr. and Trump's pick for the Pentagon. And: Fighting back. New reporting on the top House Democrat's plans to bring his party out of the wilderness. Learn more about your ad choices. Visit podcastchoices.com/adchoices ..read more

First: Kamala Harris is camping out in Michigan, Wisconsin, and Pennsylvania this week as it becomes increasingly clear that her best path to the White House leads straight through those crucial states.  Plus: The Trump campaign reportedly wants Nikki Haley to join him on the trail during the campaign's final days. So why this morning did the former president take a swipe at her?  And: Too close for comfort. That's how the architect of Obama's presidential campaign, David Plouffe, sums up this race. He joins us exclusively.  Learn more about your ad choices. Visit podcastch ..read more

Hurricane Milton continues its inexorable march toward Florida as a catastrophic Category 4 storm, packing winds of 145 miles per hour. Milton is now forecast to make landfall just south of Sarasota, and its outer bands are already wreaking havoc on millions, producing large and dangerous tornadoes.  Learn more about your ad choices. Visit podcastchoices.com/adchoices ..read more

Hurricane Milton is packing catastrophic winds of 150 miles per hour and barreling straight toward Florida, with Tampa in the storm's bullseye. We get an update from the city's mayor, who's already issued a blunt warning: "If you stay in one of the evacuation zones, you are going to die."  Learn more about your ad choices. Visit podcastchoices.com/adchoices ..read more