Breathing Oxygen Back into the Biological Conversation
GEN Sounds of Science Podcast
by Genetic Engineering and Biotechnology News
1y ago
As good scientific investigators, we strive to make our research more reproducible, repeatable, and translatable. These traits are ostensibly engrained in researchers from the start of their careers but often fall to the wayside in pursuit of experimental answers. Throughout this three-episode podcast series, sponsored by The Baker Company, we will weave the common thread of these essential research traits and discuss some ubiquitous techniques common to so many laboratories—focusing on areas that are often overlooked but can have a considerable impact on recapitulating physiological condition ..read more
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Global Single-Use Network Supports Assurance of Supply
GEN Sounds of Science Podcast
by Genetic Engineering and Biotechnology News
1y ago
Single-use systems have been steadily climbing toward the top of the tools utilized by biomanufacturers for the commercial-scale production of critical therapeutic products. However, COVID-19 created an inflection point for this technology, generating an even greater demand that will shape the market for many years. Yet, with considerable demand comes the need to focus on the key aspects driving growth while discovering the appropriate solutions to the challenges that invariably arise when technologies are being developed and utilized rapidly. This is our third and final episode of GENcast, w ..read more
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Resins Address Downstream Purification Concerns
GEN Sounds of Science Podcast
by Genetic Engineering and Biotechnology News
1y ago
The demand for safe and efficacious biologics has accelerated exponentially in the past several years due to the tremendous success of some of the initial therapeutic offerings in this space. Yet, along with this increased demand comes the need for innovative solutions to improve downstream production workflows. For example, eliminating purification bottlenecks and improving overall yields from chromatography steps can significantly impact the final product’s cost. In this second episode of GENcast with Executive Vice President of Biopharma Production at Avantor, Dr. Ger Brophy, we dive into ..read more
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Mechanistic Modeling Improves Drug Discovery Workflows and Speeds Therapeutic Development
GEN Sounds of Science Podcast
by Genetic Engineering and Biotechnology News
1y ago
This is the final episode in our three-part GENcast series, where we discuss the virtues of mechanistic modeling and how it can significantly impact critical decision-making points in the drug discovery process, especially as drug developers move closer toward the IND process. In our two previous podcasts, we were introduced to mechanistic modeling concepts and the basics of how they can be applied to drug discovery workflows. You can listen to the earlier podcasts with the following links: episode 1, episode 2. In this latest GENcast, I met up once again with Dr. John Burke, Preside ..read more
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Moving the Drug Pipeline Forward with Mechanistic Modeling
GEN Sounds of Science Podcast
by Genetic Engineering and Biotechnology News
1y ago
This is part two in our three-part GENcast series, where we discuss various aspects of the drug discovery and development process and, in particular, how advanced computational techniques like mechanistic modeling can help advance the therapeutic drug pipeline for many developers. In our initial podcast, we were introduced to mechanistic modeling concepts and the basics of how they can be applied to drug discovery workflows. In this latest GENcast, I sat down once again with Dr. John Burke, President, CEO, and Co-founder of Applied BioMath, to take a deeper dive into the specific applicat ..read more
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Reducing Drug Discovery and Development Risk with Mechanistic Modeling
GEN Sounds of Science Podcast
by Genetic Engineering and Biotechnology News
1y ago
The drug discovery and development process can be an arduous endeavor. Manufacturers spend considerable resources and money chasing down potential candidate molecules to create a potential new therapeutic—often resulting in abandoning the candidate in the very later stages of development due to minor factors that might have been overlooked at the onset of the discovery process. Thankfully, there have always been those investigators who sought to merge the fields of mathematics and biology while taking advantage of advanced computing algorithms to help inform and de-risk drug discovery decision ..read more
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Meet the Editor-in-Chief of GEN Biotechnology: Hana El-Samad, PhD
GEN Sounds of Science Podcast
by Genetic Engineering and Biotechnology News
2y ago
GEN Biotechnology is the new peer-reviewed journal launching in early 2022 by Mary Ann Liebert Inc. aiming to publish outstanding original research and perspectives across the biotech field. In this Q&A, GEN Biotechnology Senior Editor, Fay Lin, PhD, interviews Editor-in-Chief, Hana El-Samad, PhD, about her scientific research, outreach, and vision for the journal. Learn more about GEN Biotechnology: Website: www.genbiotechjournal.com Twitter: @GENBiotechJrnl Send editorial inquiries to editor@genbiotechjournal.com See acast.com/privacy for privacy and opt-out information ..read more
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Interrogating the Links Between Genetics and Depression with High Throughput Assays
GEN Sounds of Science Podcast
by Genetic Engineering and Biotechnology News
2y ago
See acast.com/privacy for privacy and opt-out information ..read more
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Navigating the Regulatory Terrain during Cell & Gene Therapy Production
GEN Sounds of Science Podcast
by Genetic Engineering and Biotechnology News
2y ago
Navigating the Regulatory Terrain during Cell & Gene Therapy Production by Genetic Engineering and Biotechnology News See acast.com/privacy for privacy and opt-out information ..read more
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Solve Your Biotherapeutic Challenges with Help from Gene Therapy University
GEN Sounds of Science Podcast
by Genetic Engineering and Biotechnology News
2y ago
Solve Your Biotherapeutic Challenges with Help from Gene Therapy University by Genetic Engineering and Biotechnology News See acast.com/privacy for privacy and opt-out information ..read more
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