
Nature Aging
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Nature Aging is an online-only thematic journal publishing research articles, reviews, news and opinion pieces from across the broad field of aging research.
Nature Aging
4d ago
Nature Aging, Published online: 30 May 2023; doi:10.1038/s43587-023-00437-7
Age-associated PDGF-C drives breast cancer metastatic relapse ..read more
Nature Aging
4d ago
Nature Aging, Published online: 29 May 2023; doi:10.1038/s43587-023-00424-y
Microglia, the innate immune cells of the brain, exhibit diverse functions and can influence Alzheimer’s disease progression. This study explores human microglial diversity in Alzheimer’s disease, uncovering unique disease-associated microglial populations and predicting underlying gene regulatory networks ..read more
Senescence-induced immune remodeling facilitates metastatic adrenal cancer in a sex-dimorphic manner
Nature Aging
4d ago
Nature Aging, Published online: 25 May 2023; doi:10.1038/s43587-023-00420-2
The mechanisms underlying the influence of aging on cancer are incompletely understood. Warde et al. establish a new model of age- and sex-dependent adrenal cancer. Their work uncovers a tumor-protective role for myeloid immune cells that is enhanced by androgens ..read more
Nature Aging
4d ago
Nature Aging, Published online: 25 May 2023; doi:10.1038/s43587-023-00430-0
The promise of AI and technology to improve quality of life and care for older adults ..read more
Nature Aging
4d ago
Nature Aging, Published online: 25 May 2023; doi:10.1038/s43587-023-00435-9
Liu and colleagues investigate the effects that ovarian aging may have in granulosa cell-to-oocyte communication and demonstrate that oocyte rejuvenation and the extension of reproductive lifespan is possible by increasing lipid metabolism in granulosa cells in mouse ..read more
Nature Aging
4d ago
Nature Aging, Published online: 22 May 2023; doi:10.1038/s43587-023-00421-1
Although vaccination drops COVID-19 mortality in older adults, post-vaccine fatal COVID-19 in nursing home outbreaks was linked to Delta, Gamma and Mu variants, persistently detected in aerosols. Mortality was predicted by IFNB1 or age, ORF7a and ACE2 mRNAs ..read more
Nature Aging
4d ago
Nature Aging, Published online: 22 May 2023; doi:10.1038/s43587-023-00418-w
Reply to: Comparator choices in pharmacoepidemiology studies of Alzheimer’s disease ..read more
Nature Aging
4d ago
Nature Aging, Published online: 22 May 2023; doi:10.1038/s43587-023-00417-x
Comparator choices in pharmacoepidemiology studies of Alzheimer’s disease ..read more
Nature Aging
2w ago
Nature Aging, Published online: 19 May 2023; doi:10.1038/s43587-023-00434-w
Quantification of tau peptides in blood samples using a new mass spectrometry method suggests that individual phosphorylated tau peptides have distinct patterns of emergence in Alzheimer’s disease and differential associations with amyloid and tau pathologies. This method has the potential to stage patients along the disease continuum and for clinical trials ..read more
Nature Aging
2w ago
Nature Aging, Published online: 18 May 2023; doi:10.1038/s43587-023-00403-3
This Review provides an update on the most promising blood-based biomarkers relevant to Alzheimer’s disease and how they can be used to substantially improve the diagnostic and prognostic work-up in clinical practice and trials ..read more