Imran House and Junyun Lai Discuss CRISPR Screening in Immuno-Oncology
CRISPR Cuts
by Synthego
2M ago
Imran House, Ph.D. and Junyun Lai Ph.D. are Senior Scientists at the biotech start-up, oNKo-Innate in Melbourne, Australia that focuses on developing immuno-oncology therapies. In this episode, they discussed what they do at oNKo-innate, their career transitions from leaving academics to entering the biotech industry, and how CRISPR is impacting cancer-immunotherapy development. They also discussed overcoming common obstacles faced when developing cytokine therapies and future outlooks on clinical trials using these kinds of therapies.   Reach out and connect with both Imran and Junyun on ..read more
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Mark DeWitt and Don Kohn Discuss Their ex vivo CRISPR-based Therapy to Cure Sickle Cell Anemia
CRISPR Cuts
by Synthego
6M ago
Dr. Mark DeWitt Ph.D., Associate Director at Mammoth Biosciences, and Dr. Don Kohn M.D., distinguished professor and Director of the UCLA Human Gene and Cell Therapy Program and CIRM grantee sat down with us to discuss their latest clinical trials to cure sickle cell anemia, how synthetic guides accelerated their journey from the bench to the clinic, and their experience in the cell and gene therapy space ..read more
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Bryan Dechairo Envisions an Accessible Future for CRISPR Diagnostics
CRISPR Cuts
by Synthego
1y ago
In this episode, Bryan Dechairo, CEO of Sherlock Biosciences, talks about the impact of technology advances in the field of CRISPR diagnostics, his experiences leading Sherlock Biosciences, and his team’s mission of accessibility.  ..read more
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Ayal Hendel Talks About CRISPR in Bubble Boy Disease
CRISPR Cuts
by Synthego
2y ago
Dr. Ayal Hendel, a genome-editing pioneer and group leader at Bar Ilan University in Israel, was one of the first researchers to use modified synthetic sgRNA to edit primary cells with CRISPR. In this episode, Dr. Hendel shares his perspectives on the recent CRISPR advancements and his work on the bubble boy disease ..read more
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Jimi Olaghere Opens up About His Sickle Cell Disease and CRISPR Trial
CRISPR Cuts
by Synthego
2y ago
Jimi has dealt with sickle cell disease, a genetic disorder with serious implications, his entire life. Undergoing a CRISPR gene editing trial turned his hope for a cure into reality with promising results from the early phases. Tune in to learn about Jimi's journey in this episode.  ..read more
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TJ Cradick Speaks About Their HIV CRISPR Therapy in Trials
CRISPR Cuts
by Synthego
2y ago
TJ Cradick, Chief Scientific Officer at Excision Bio, discusses their CRISPR HIV therapy that recently proceeded into clinical trials in this episode and their ongoing work on other viral diseases.  ..read more
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Bryce Olson Relays His Experience on Personalized Therapies for Cancer Patients
CRISPR Cuts
by Synthego
2y ago
After being diagnosed with aggressive prostate cancer, Bryce Olson quickly learned the science behind it and has leveraged NGS to understand his tumor genomics and find opportunities in personalized therapies. Hear the patient perspective for the first time on our podcast through Bryce's narration of his experience and pursuit of next generation cell and gene therapies.  ..read more
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Neville Sanjana Discusses Ways to Enhance CRISPR-Cas13 Knockdown in Human Cells
CRISPR Cuts
by Synthego
2y ago
In this collaboration episode with NEB, we interview Dr. Neville Sanjana, a core faculty member at the New York Genome Center, about his recent publication in which chemically modified guide RNAs were used to enhance CRISPR-Cas13 knockdown in human cells ..read more
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Kiana Aran Chats About her Nature Award and New Non-Profit
CRISPR Cuts
by Synthego
2y ago
In this episode, we chat with Dr. Kiana Aran, the CSO of Cardea Bio and associate professor at Keck Graduate Institute, who recently won the Nature Research Award for Inspiring Women in Science. Dr. Aran talks about her experience being a nominee and award winner, her early days and scientific journey, and the launch of her new non-profit, Aran Nebula ..read more
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6 Women CRISPR Leaders Get Candid About Their Journeys to the Top
CRISPR Cuts
by Synthego
2y ago
We chatted with six female leaders in the CRISPR—Alison van Eenennaam, Ph.D., Kiana Aran, Christina Trojel-Hansen, Ph.D., Laura Lambert, Ph.D., Elena Miñones Moyano, Ph.D., and Samantha Maragh, Ph.D.— about their professional journeys.  Tune in to this episode for a candid and honest discussion on a broad range of topics, including their experiences as women of color, life as working moms, adjusting in male-dominated fields, experiences being part of the LGBTQIA community, and the role of mentors in professional development ..read more
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