Freely Filtered | A NephJC Podcast
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This podcast is a twice monthly recap of the NephJC journal club.
Freely Filtered | A NephJC Podcast
1M ago
The Filtrate:
Joel Topf
Swapnil Hiremath
Jordy Cohen
AC Gomez
With Special Guest:
Tim Anderson @TimAndersonMD
Editor:
Priya Yenebere
Show Notes
Clinical Outcomes of Intensive Inpatient Blood Pressure Management in Hospitalized Older Adults
NephJC Summary | PubMed | JAMA Internal Medicine
The Jordy AC collab: An Interactive Ambulatory Nephrology Curriculum for Internal Medicine Interns: Design, Implementation, and Participant Feedback (PubMed)
Clinical Outcomes After Intensifying Antihypertensive Medication Regimens Among Older Adults at Hospital Discharge (PubMed)
Trends in Blood Pressure Trea ..read more
Freely Filtered | A NephJC Podcast
1M ago
How Medicine Works, and When It Doesn’t
Amazon
The Filtrate:
Joel Topf
Josh Waitzman
Jennie Lin
With Special Guest:
Jade Teakell
Perry Wilson
Editor:
Joel Topf
Show Notes
Understanding Medical Research: Your Facebook Friend is Wrong. Coursera
Illusory truth effect (Wikipedia)
Number needed to treat (Wikipedia)
NNT at MedPage Today:
NNT on NephJC
Deaths of Despair:
Suicide (CDC 2001-2021)
Drug Overdose (CDC 2001-2021)
Steve Jobs delayed therapy for his treatable pancreatic cancer (ABC News)
Residents are unionizing at Mass General Brigham. Here's what you need to know (WBUR)
Pi and bouncing bri ..read more
Freely Filtered | A NephJC Podcast
2M ago
The Filtrate:
Joel Topf
Nayan Aurora
Sophia Ambruso
With Special Guest:
Michael Collins
Editor:
Nayan Aurora
Show Notes:
Twitter is now X (NYT)
Michael Collins (the astronaut, not the real one)
PlasmaLyte by Baxter
NephJC BEST Fluids summary
Early Goal Directed Therapy for Sepsis NEJM manuscript which changed practice patterns and welcomed in an era of massive fluid resuscitation.
PLUS Trial NEJM
SPLIT Trial JAMA
BaSICS NephJC Summary
SALTED and SMART NephJC Summary
Adaptive minimization wikipedia
BEST Fluids statistical plan
BEST Fluids in CLinicalTrials.gov
Delayed Graft Function review in ..read more
Freely Filtered | A NephJC Podcast
6M ago
The Filtrate:
Joel Topf
Swapnil Hiremath
Sophia Ambruso
AC Gomez
With Special Guest:
Amit Garg (@AmitXGarg) Nephrologist at Western University, London, and lead PI of the EnAKT LKD trial.
Susan Q. McKenzie (LinkedIn) Co-Founder & Chair, Transplant Ambassador Program. President of the Kidney Patient and Donor Alliance of Canada.
Editor:
Joel Topf
Show Notes:
Late Braking and High Impact Clinical Trial press release
JAMA Internal Medicine
MyTEMP trial Personalised cooler dialysate for patients receiving maintenance haemodialysis (MyTEMP): a pragmatic, cluster-randomised trial (PubMed ..read more
Freely Filtered | A NephJC Podcast
7M ago
The Filtrate:
Joel Topf
Jennie Lin
Josh Waitzman
With Special Guest:
AC Gomez MedPeds nephrology fellow at Mass General/Brigham and Boston Children’s | Twitter
Gentian Hall Assistant Professor of Medicine Duke Department of Medicine
Editor:
Sophia Ambruso
Show Notes:
APOL1 review by the OG Scientists APOL1 Nephropathy: From Genetics to Clinical Applications
MYH9 and APOL1 connection: The population genetics of chronic kidney disease: insights from the MYH9–APOL1 locus
Martin Pollack Lab
Vertex Lab
Worldwide Frequencies of APOL1 Renal Risk Variants (NEJM)
Kidney Disease-Associated APOL1 Variant ..read more
Freely Filtered | A NephJC Podcast
7M ago
Bicarbonate did not slow the loss of GFR in this well done Swiss, single-blind study of transplant patients.
The Filtrate:
Joel Topf
Nayan Arora
Swapnil Hiremath
Pirya Yenebere
With Special Guest:
Nav Tangri nephrologist and epidemiology at the University of Manitoba
Editor:
Nayan Arora
Show Notes:
Arsenal FC
The London study that kicked it all off!
de Brito-Ashurst, I., Varagunam, M., Raftery, M. J., & Yaqoob, M. M. (2009). Bicarbonate supplementation slows progression of CKD and improves nutritional status. Journal of the American Society of Nephrology: JASN, 20(9), 2075–2084.
The multi ..read more
Freely Filtered | A NephJC Podcast
7M ago
The Filtrate:
Joel Topf
Nayan Arora
Swapnil Hiremath
Pirya Yenebere
With Special Guest:
Nav Tangri nephrologist and epidemiology at the University of Manitoba
Editor:
Nayan Arora
Show Notes:
Arsenal FC
The London study that kicked it all off!
de Brito-Ashurst, I., Varagunam, M., Raftery, M. J., & Yaqoob, M. M. (2009). Bicarbonate supplementation slows progression of CKD and improves nutritional status. Journal of the American Society of Nephrology: JASN, 20(9), 2075–2084.
The multi center (but unblinded) UBI Study with mortality benefit!
Di Iorio, B. R., Bellasi, A., Raphael, K. L., Santo ..read more
Freely Filtered | A NephJC Podcast
10M ago
The Filtrate:
Joel Topf
Nayan Arora
Sophia Ambruso
With Special Guest:
Boback Ziaeian @boback Assistant Professor of Medicine David Geffen School of Medicine at UCLA. His Google Schoolar page is better than yours.
And returning for her fourth time (why do we keep inviting her back?)
Sadiya Khan @heartDocSadiya Assistant Professor of Medicine (Cardiology) and Preventative Medicine at Northwestern Feinberg School of Medicine. Link
Editor:
Priya Yenebere
Show Notes:
Diuretic Therapy review by. Craig Brater NEJM
The manuscript in JAMA | NephJC
Metoprolol vs Carvedilol: Comparison of carvedilol a ..read more
Freely Filtered | A NephJC Podcast
10M ago
The Filtrate:
Joel Topf
Swapnil Hiremath
Josh Waitzman
Nayan Arora
Sophia Ambruso
With Special Guest:
Megan Prochaska Assistant professor of medicine at University of Chicago
John Asplin Medical Director Consultant LithoLink (Twitter)
Editor:
Joel Topf
Show Notes:
The LithoLink website
Stone Camp tweet
Prevention of Repeated Episodes of Kidney Stones in Adults: A Clinical Practice Guideline From the American College of Physicians (link)
NOSTONE in the NEJM and NephJC
Fred Coe Google Scholar | YouTube | Blog
Hypercalcuria. Curhan et al. 24-h uric acid excretion and the risk of kidney stones ..read more
Freely Filtered | A NephJC Podcast
1y ago
The Filtrate:
Joel Topf
Swapnil Hiremath
Josh Waitzman
Jordy Cohen
With Special Guest:
Areef ishani lead author and Chief of Medicine VA Minneapolis
Editor:
Nayan Arora
Show Notes:
MRFIT switches diuretics and finds better outcomes.
Swapnil shows how many studies he is familiar with by spewing out a string of them.
Chlorthalidone wins: ALLHAT, MRFIT, SPRINT, HYVET, CLICK (not mentioned by Swap but by Jordy later)
HCTZ loses: HOPE3, ACCOMPLISH
Diuretic half-lifes NEJM review
Edarbyclor: Azilsartan and Chlorthalidone $240/month as per GoodRx
Nice mention of late study originator Frank Lederle ..read more