Introducing the Johns Hopkins Malaria Minute
Malaria Minute
by Thomas Locke
2y ago
The post Introducing the Johns Hopkins Malaria Minute appeared first on The Fight Malaria Blog ..read more
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How Drug Resistance Is Impacting Malaria Elimination
Malaria Minute
by Thomas Locke
3y ago
The Latest Malaria News, in 60 Seconds. Researchers detail the extent of antimalarial drug resistance around the world, considering its implications for the WHO’s Global Technical Strategy for Malaria. https://d3ctxlq1ktw2nl.cloudfront.net/staging/2021-3-8/173545175-44100-2-7dd5fcb1d97da.m4a Malaria Minute on iTunes and Spotify Transcript: Five years ago, the WHO announced their Global Technical Strategy for Malaria which aims to reduce the global burden of the disease by 90% by 2030.  Yet, despite ambitious targets, progress against the disease has stalled and among the threats to regain ..read more
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New Insights Into the Biophysical Characteristics of RTS,S Antibodies
Malaria Minute
by Thomas Locke
3y ago
The Latest Malaria News, in 60 Seconds. Researchers reveal the importance of antibody affinity and dissociation constant in parasite neutralisation. https://d3ctxlq1ktw2nl.cloudfront.net/staging/2021-1-18/156526190-44100-2-d37d459ed55c4.m4a Malaria Minute on iTunes and Spotify Transcript: The leading malaria vaccine candidate, RTS,S, targets the circumsporozoite protein and offers partial protection against the disease, with around 40% efficacy. To better understand which antibody features improve protection from the parasite, researchers from the Scripps Research Institute and the Johns Hopki ..read more
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Researchers Use AI to Identify Morphologically Similar Mosquitoes
Malaria Minute
by Thomas Locke
3y ago
The Latest Malaria News, in 60 Seconds. Researchers develop an image recognition tool to identify mosquitoes in the field, and a new paper highlights the nuanced realities of malaria decision-making in endemic regions. https://d3ctxlq1ktw2nl.cloudfront.net/staging/2020-11-23/140466283-44100-2-c8f45f18b1d57.m4a Malaria Minute on iTunes and Spotify Transcript: New research has demonstrated that Artificial Intelligence (AI) can be applied to malaria surveillance, helping identify the sex, genus, species and strain of mosquitoes in the field. Using a library of mosquito images, researchers develop ..read more
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Shedding Enzyme Essential for Parasite Survival
Malaria Minute
by Thomas Locke
3y ago
The Latest Malaria News, in 60 Seconds. Researchers find that SUB2, a malaria parasite enzyme, helps the parasite survive in the human host and new research characterises cerebral malaria infection in adults and children. https://d3ctxlq1ktw2nl.cloudfront.net/staging/2020-11-16/138624796-44100-2-3cf478b0439d5.m4a Malaria Minute on iTunes and Spotify Transcript: For the malaria parasite to survive in the human host, it must invade and replicate inside red blood cells. During this process, a number of parasite proteins are shed. Researchers have now identified that a malaria parasite enzyme, cal ..read more
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Parasite Biomarkers Predict Transmission Potential
Malaria Minute
by Thomas Locke
3y ago
The Latest Malaria News, in 60 Seconds. Researchers identify three biomarkers associated with gametocytes development that predict transmission potential, and the use of LAMP-based malaria diagnostic tools is evaluated. https://d3ctxlq1ktw2nl.cloudfront.net/staging/2020-11-9/136486146-44100-2-9779558dced12.m4a Malaria Minute on iTunes and Spotify Transcript: Researchers have identified three malaria parasite biomarkers that offer an early indication of infected individuals’ transmission potential. The transmissible form of the parasites, the gametocytes, are sequestered out of blood circulatio ..read more
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WHO Publish Annual World Malaria Report
Malaria Minute
by Thomas Locke
3y ago
The Latest Malaria News, in 60 Seconds. The WHO publishes its annual World Malaria Report and a new article stresses the need for highly-effective vaccines to eliminate malaria. https://d3ctxlq1ktw2nl.cloudfront.net/staging/2020-11-3/134331863-44100-2-80a95dd6b5794.m4a Malaria Minute on iTunes and Spotify Transcript: The WHO published its annual World Malaria Report this week, highlighting success over the past two decades but stressing the need to get back on track. Despite a 60% reduction in global malaria deaths over the past twenty years, landmark goals for malaria elimination, set in 2015 ..read more
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Conserved Antigen Pb22 Plays a Critical Role in Male Gametogenesis in P. Berghei
Malaria Minute
by Thomas Locke
3y ago
The Latest Malaria News, in 60 Seconds. Pb22, a protein expressed by Plasmodium berghei, may play an important role in the transmission of malaria, and review on the use of tafenoquine finds that the drug is well-tolerated and effective. https://d3ctxlq1ktw2nl.cloudfront.net/staging/2020-10-26/132152443-44100-2-c3c122513c848.m4a Malaria Minute on iTunes and Spotify Transcript: Pb22, a protein expressed by the mouse malaria parasite Plasmodium berghei, may play an important role in the transmission of malaria. In parasites without the protein, less exflagellation was recorded in vitro, and the ..read more
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Parasite Viability Is a Superior Indicator of Antimalarial Drug Activity
Malaria Minute
by Thomas Locke
3y ago
The Latest Malaria News, in 60 Seconds. Determining drug efficacy through parasite clearance half-life may underestimate the activity of some antimalarial drugs, and the WHO publishes new guidance on the use of genetically modified mosquitoes. https://d3ctxlq1ktw2nl.cloudfront.net/staging/2020-10-18/129902732-44100-2-5d2a4b4fb86ac.m4a Malaria Minute on iTunes and Spotify Transcript: The gold standard for assessing the efficacy of antimalarial drugs is to measure the parasite clearance half-life: the time it takes for the number of circulating parasites to be reduced by half. New research has ..read more
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‘Memory-Like’ Imprints in γδ T Cells Allow for Better Response to Future Malaria Infection
Malaria Minute
by Thomas Locke
3y ago
The Latest Malaria News, in 60 Seconds. New research examines the long-term impact of malaria infection on γδ T cells, and a review of malaria cases among pregnant women in Lagos, Nigeria, explores the impact of preventative measures on the prevalence of malaria and anaemia. https://d3ctxlq1ktw2nl.cloudfront.net/staging/2020-10-12/127806465-44100-2-02fe3df2483e7.m4a Malaria Minute on iTunes and Spotify Transcript: New research has examined the long-term impact of malaria infection on γδ T cells, which are involved in the immune response against the parasites. Researchers identified the develo ..read more
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