With CBD taking center stage this year, there has been increased coverage of this “miracle” compound in the news. But it’s important to remember that THC is also a very important cannabinoid with some very powerful properties. While many enjoy the calming benefits of CBD without the psychoactive effects, dose-dependent effects of THC can be very beneficial for a variety of medical conditions. Cannabis science has rapidly advanced in the past year, with studies published in top-tier journals on CBD, THC, and CBD:THC. By comparing and contrasting the isolated effects of each of these compounds a ..read more

Dr. Adam Abodeely discusses CBD and COVID19. The post Cannabinoid Educational Series: An update on COVID-19: Understanding the interaction between our Endocannabinoid System and our Immune System. appeared first on CBD Health and Wellness ..read more

One of the greatest results of cannabis legalization has been the implantation of current methods and technology from the scientific sector into the cannabis industry. That technology and human talent has driven great strides in cannabinoid production. One has been the incorporation of CBD into a water-soluble format, which allows greater integration into foods and beverages. Another has been the promising application in the incorporation of microbial cannabinoid expression vectors into the repertoire of CBD manufacturing processes. The challenges with the last methods include specific enzymes ..read more

Beyond finding CBD products in natural health food stores, vitamin shops, and health care offices, they are also taking over the shelves of cafes, vape shops, salons, and even gas stations. But many CBD consumers may not fully understand what’s in their CBD or what makes each product different. Misinformation, or at best, vague information is abundant in this market. In order to combat misinformation, there are a couple of key starting points that can include but are not limited to 1) Understanding the differences in sourcing of ingredients and 2) Understanding what types of information can le ..read more

Cannabis policy changes are moving quickly throughout the US. With the passing of recent hemp legislation, members of the cannabis industry have a lot to look forward to this year, including state-by-state cannabis legalization. However, to better prepare for the future, it’s important to take a look back to where and how cannabis was first used both medicinally and recreationally and why it eventually became a prohibited substance not too long ago in its history. From an ancient remedy to recreational use to a widely-studied and controversial substance, cannabis still manages to create excite ..read more

Opiates are a pharmacological class of analgesic drugs used to treat moderate to severe pain. However, there are many drawbacks and side effects for even moderate opiate use. Research has shown that continued opioid use in chronic pain patients may even have an antagonistic, sensitizing effect on pain receptors, actually decreasing the pain threshold while simultaneously causing the development of a dependence. This has lead to the addiction crisis currently known as the ‘Opioid epidemic.’ Recently, CBD-enriched cannabis has been shown in the laboratory setting to provide mild to moderate pain ..read more

In September 2018, the Drug Enforcement Agency (“DEA”) placed Epidiolex—a CBD-based drug used to treat severe forms of epilepsy—in Schedule V of the Controlled Substances Act (“CSA”), the lowest classification under the CSA.  That re-scheduling, however, was limited in scope: only drugs approved by the Food and Drug Administration (“FDA”) and containing no more than .01 percent THC were re-scheduled.  CBD, a derivative of “marihuana,” remains a Schedule I substance in the eyes of the DEA.   This panel will explore the impact of the DEA’s re-scheduling of Epidiolex; what effect ..read more

Over the past year, CBD has found its way into the hands of many, some of whom are experienced cannabis users and some of whom are novices that regard it as a supplement or health trend. However, standardization and testing of these products have not quite caught up in speed to its surge in use. Many of these difficulties have stemmed from differences in state-by-state regulations and policies, which are quickly evolving over the span of months. National, consensus guidelines must be adapted to establish consistency across protocols, as the CBD current supply chain is far behind in establishin ..read more

CBD has enjoyed quite a popular run this year – from humble cannabinoid second to THC to FDA-approved medicine. CBD is popping up in vape shops and cafes and is readily available to purchase all over the Internet. But not all CBD products are the same. And a JAMA paper published last year reported that, of 84 CBD products from 31 companies tested, less than one-third were labeled accurately. To avoid these pitfalls, consumers must look out for the following in their CBD products – the type of extraction method used, where the product came from (region the cannabis/hemp was grown and produced ..read more

Cannabinoids are interesting therapeutic molecules because they do not act the same as most pharmaceutical drugs. Rather than strongly binding to a single target in the body, many cannabinoids only weakly connect with targets or affect receptors in a process called allosteric regulation. They also reinforce each other’s behavior, with the presence of one cannabinoid causing increased sensitivity to the activity of another. These findings could help explain the results of a 2015 study published in the journal Pharmacology & Pharmacy, where researchers at the Hebrew University of Jerusalem c ..read more