M A N O X B L O G | | Industrial Management Blog
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M A N O X B L O G | | Industrial Management Blog
1M ago
The world of cannabis has undergone an outstanding transformation. From once being a business operated in the dark, cannabis has now become one of the fastest-growing industries in the United States.
Today, the global cannabis market is worth billions of dollars, all thanks to the increasing number of states legalizing it. In the U.S., it’s now easier than ever to get cannabis products, this industry has been growing rapidly for the past five years, and it is not going to stop now.
The cannabis industry is expanding so fast that it’s becoming a bit tricky to keep up with all the amazing progre ..read more
M A N O X B L O G | | Industrial Management Blog
1M ago
Key Findings
Thermal rather than photodegradation was the more significant pathway for reduced potential THC.
The most significant reductions in potential THC occurred in the first 30 days, regardless of storage conditions.
INTRODUCTION
Cannabis (Cannabis sativa L) is an agricultural commodity that secretes a resin containing a specific class of terpenophenolic compounds called cannabinoids. Cannabinoids are relatively unstable and are known to change or degrade over time — however, limited research exists to determine the rate at which this occurs under different storage cond ..read more
Decentralized Clinical Trials for Drugs, Biological Products, and Devices Guidance Free download PDF
M A N O X B L O G | | Industrial Management Blog
1M ago
This draft guidance provides recommendations for sponsors, investigators, and other stakeholders regarding the implementation of decentralized clinical trials (DCTs) for drugs, biological products, and devices. In this guidance, a DCT refers to a clinical trial where some or all of the trial-related activities occur at locations other than traditional clinical trial sites. In fully decentralized clinical trials, all activities take place at locations other than traditional trial sites. These trial-related activities may take place at the homes of trial participant ..read more
M A N O X B L O G | | Industrial Management Blog
1M ago
Will the hype around psychedelics turn into a bad trip for pharma? Or, as some have suggested, will they provide a future for mental health drug development that’s bigger than weed?
Albert Hofmann had an odd feeling about the “apparently useless” compound he discovered at Sandoz Laboratories in 1938 — but he couldn’t figure out why. Originally, his team at Sandoz, at the time a Swiss chemical company known for manufacturing dyes and saccharine, was researching the biological compounds in ergot, a fungus that grows on moldy rye bread. Inside Sandoz, (which is now a division of Novartis), scien ..read more
M A N O X B L O G | | Industrial Management Blog
1M ago
Barentz formula includes avocado oil.
Phase A
Water
72.45
Farmal Xanthan Gum 2312 TC (Ingredion)
0.25
Glystar A-31 (Ingredion) (Sorbitol (and) Glycerin)
4.67
Innovaloe Aloe 200X (AMB Wellness) (Aloe Barbadensis Leaf Juice Powder)
0.10
Phase B
Lincamuul CTA (Cetearyl Alcohol)
1.50
Innollient LO (Innovacos) Octyldodecyl Oleate (and) Octyldodecyl Stearoyl Stearate (and) Polyhydroxystearic Acid (and) Octyldodecanol)
3.20
Stearic Acid
3.33
PolyAquol LW (Innovacos) (Polyglyceryl-4 Laurate (and) Polyglyceryl-6 Laurate)
4.50
Avocado Oil (IndyK) (Persea Gratissima (Avocado) O ..read more
M A N O X B L O G | | Industrial Management Blog
1M ago
A guide to help the cosmetic chemist develop cannabidiol-based personal care formulas.
Tom Branna, Editorial Director03.31.22
Cannabidiol (CBD) shows plenty of promise in topical skin care formulas. CBD is a natural, highly-effective anti-inflammatory as well as an emollient. It is said to be particularly useful for consumers with sensitive skin, inflammation, redness and dehydration. Experts say CBD provides the strongest anti-inflammatory protection, while fighting irritation and minimizing redness.
Formulators know there are plenty of benefits to adding CBD to a personal care formula. At th ..read more
M A N O X B L O G | | Industrial Management Blog
1M ago
Regulated versus unregulated cannabis — In addition to limiting interactions with the unregulated market and with the criminal justice system, regulated cannabis is safer and more predictable. Unregulated cannabis has been found in many studies to be contaminated with harmful pesticides, heavy metals, molds, microbes, or mycotoxins [14-19]. Most states with legalized cannabis test regulated cannabis for these contaminants, in addition to confirming cannabinoid dosing and labeling [6,18]. However, the ways in which regulation and testing are implemented differ by state. (See ‘Med ..read more
M A N O X B L O G | | Industrial Management Blog
2M ago
An estimated 77% of Americans report they take some form of dietary supplement as part of their regular health regimen with adults age 35-54 topping the charts at 81%. Dietary supplements are only one corner of the health product market with sports supplements and general consumer goods routinely finding their way into our shopping carts. These are five of the most common health products in 2019.
Herbal Supplements
Herbal supplements are a multi-billion dollar global industry that is expected to hit $8.5 billion by 2025. The most popular herbal supplement is echinacea, with over 14 million Am ..read more
M A N O X B L O G | | Industrial Management Blog
2M ago
BIOACCESSIBILITY & BIOAVAILABILITY
Understanding how the physicochemical attributes may affect the bioaccessibility and hence the bioavailability is also critical to developing and delivering a safe and effective dietary supplement.1,2 Water-soluble components are easier to work with and can fit with a variety of delivery formats. Conversely, poorly soluble or insoluble ingredients present a significant challenge.3,4 A particularly challenging subset of ingredients are fat-soluble or lipophilic materials that must be formulated carefully to attain optimal absorption. Bioacce ..read more
M A N O X B L O G | | Industrial Management Blog
2M ago
The legal cannabis industry is comprised of the production and sale of the cannabis plant and products derived from it. Many companies in this sector began in supplying the medical market when that was all that existed. The legal markets in Uruguay, Canada, Thailand and the United States have led to new companies as well as expansion of previously medical only suppliers.
Main highlight by the Country:
Portugal’s progressive drug policies have made it a hotbed for cannabis tourism, attracting visitors from around the world.
Australia’s cannabis market is experiencing significant growth as the c ..read more