TWiEVO 84: Decoding our defenses to the Black Death
This Week In Evolution
by Vincent Racaniello
2w ago
Nels and Vincent review the use of ancient DNA to identify loci that may have been under selection during the Black Death by studying populations before, during, and after the pandemic. Hosts: Nels Elde and Vincent Racaniello Subscribe (free): Apple Podcasts, Google Podcasts, RSS,  Become a patron of TWiEVO Links for this episode Evolution of immune genes associated with Black Death (Nature) ERAP2 and respiratory disease (medRxiv) Time stamps by Jolene. Thanks! Science Picks Nels – Interview with Paul Turner in Current Biology and Map of the World ..read more
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TWiEVO 83: Evolution spreads its wings (and then loses them)
This Week In Evolution
by Vincent Racaniello
1M ago
Florian Maderspacher from Current Biology joins Nels and Vincent to discuss a special issue of the journal on birds. Hosts: Nels Elde and Vincent Racaniello Guest: Florian Maderspacher Subscribe (free): Apple Podcasts, Google Podcasts, RSS,  Become a patron of TWiEVO Links for this episode Current Biology Birds Special Issue Scott Edwards bikes across the US (Audubon) Support Diversity Issues in Evolution (Go Fund Me) Time stamps by Jolene. Thanks! Science Picks Florian – Favorite birds of authors/contributors in Birds issue Nels –Loss of avian in ..read more
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TWiEVO 82: A genetic hack for the human brain
This Week In Evolution
by Vincent Racaniello
2M ago
Nels and Vincent consider evidence that a single amino acid change in the TKTL1 gene might have led to greater neurogenesis in the frontal cortex of modern humans compared with Neanderthals. Hosts: Nels Elde and Vincent Racaniello Subscribe (free): Apple Podcasts, Google Podcasts, RSS,  Become a patron of TWiEVO Links for this episode Human TKTL1 implies greater neurogenesis (Science) Everyone’s a little bit Neanderthal (TWiEVO 8) Tragic gene flow from Neanderthals (TWiV 676) Time stamps by Jolene. Thanks! Science Picks Nels – Unusual display of e ..read more
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TWiEVO 81: Evolution's new and improved slime molds
This Week In Evolution
by Vincent Racaniello
3M ago
Nels and Vincent discuss how duplication of a gene encoding a transcription factor led to evolution of a novel cell type in the slime mold Dictyostelium. Hosts: Nels Elde and Vincent Racaniello Subscribe (free): Apple Podcasts, Google Podcasts, RSS,  Become a patron of TWiEVO Links for this episode Gene duplication leads to novel cell type (Current Biol) Evolution of multicellularity (TWiEVO 11) Letters read on TWiEVO 81 Time stamps by Jolene. Thanks! Science Picks Nels – Dall-E artificial intelligence meets art Vincent – John Bonner’s slime mold ..read more
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TWiEVO 80: Viruses of a feather bottleneck together
This Week In Evolution
by Vincent Racaniello
4M ago
Louise Moncla joins Nels and Vincent to review her use of genomics to understand emergence, evolution, and transmission of respiratory viruses including influenza virus H5N1, mumps virus, and SARS-CoV-2. Hosts: Nels Elde and Vincent Racaniello Guest: Louise Moncla Subscribe (free): Apple Podcasts, Google Podcasts, RSS,  Become a patron of TWiEVO Links for this episode Within-host diversity of influenza virus H5N1 (PLoS Path) Mumps virus outbreak in Washington (eLive) SARS-CoV-2 tight transmission bottlenecks (PLoS Path) Time stamps by Jolene. Thank ..read more
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TWiEVO 79: When the immune system is away, SARS-CoV-2 will play
This Week In Evolution
by Vincent Racaniello and Nels Elde
5M ago
Nels and Vincent discuss an analysis of the drivers of evolution of SARS-CoV-2 during chronic infections, indicating that a tradeoff exists between antibody evasion and fitness. Hosts: Nels Elde and Vincent Racaniello Click arrow to play Download TWiEVO 79  (103 MB .mp3, 86 min) Subscribe (free): Apple Podcasts, Google Podcasts, RSS,  Become a patron of TWiEVO Links for this episode SARS-CoV-2 evolution during chronic infection (Nat Med) Letters read on TWiEVO 79 Time stamps by Jolene. Thanks! Science Picks Nels – NASA scientists say ima ..read more
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TWiEVO 78: The virus daily double
This Week In Evolution
by Vincent Racaniello
6M ago
Nels and Vincent provide an update on cases of monkeypox, and summarize a biochemical view of three changes in the SARS-CoV-2 spike protein that may balance positive and negative selection. Hosts: Nels Elde and Vincent Racaniello Subscribe (free): Apple Podcasts, Google Podcasts, RSS,  Become a patron of TWiEVO Links for this episode ECDC monkeypox risk assessment (pdf) Monkeypox virus genomes (Nextstrain) Discussion of monkeypox virus genome sequencing (virological.org) Balancing positive and negative selection in spike protein (Biochem) Time stamps by ..read more
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TWiEVO 77: The mutations of our lives
This Week In Evolution
by Vincent Racaniello
7M ago
Alex joins Nels and Vincent to discuss his work which demonstrates that somatic mutation rates scale with lifespan in mammals. Hosts: Nels Elde and Vincent Racaniello Guest: Alex Cagan Subscribe (free): Apple Podcasts, Google Podcasts, RSS,  Become a patron of TWiEVO Links for this episode Somatic mutation and age (Nature) Zombie gene in elephants (TWiEVO 26) Time stamps by Jolene. Thanks! Science Picks Alex – Paper.app Nels – Fifty years since Lewontin’s apportionment of human diversity Vincent – An Exceptional Village Listener Pick Martha – Plag ..read more
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TWiEVO 76: One-step symbiosis
This Week In Evolution
by Vincent Racaniello
8M ago
Nels and Vincent describe how a single amino acid change can allow E. coli to replace the essential gut symbiont of the stinkbug Plautia stali. Hosts: Nels Elde and Vincent Racaniello Click arrow to play Download TWiEVO 75  (103 MB .mp3, 86 min) Subscribe (free): Apple Podcasts, Google Podcasts, RSS,  Become a patron of TWiEVO Links for this episode Making E. coli an insect mutualist (bioRxiv) Letters read on TWiEVo 76 Time stamps by Jolene. Thanks! Science Picks Nels – Inequality in science and the case for a new agenda Vincent – Founda ..read more
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TWiEVO 75: Even the BANAL coronaviruses are interesting
This Week In Evolution
by Vincent Racaniello
9M ago
Nels and Vincent review isolation of SARS-CoV-2-like viruses from bats in Laos that can replicate in human cells. Hosts: Nels Elde and Vincent Racaniello Subscribe (free): Apple Podcasts, Google Podcasts, RSS,  Become a patron of TWiEVO Links for this episode SARS-CoV-2 like viruses in bats in Laos (Nature) Vampire vax (TWiV 809) Time stamps by Jolene. Thanks! Science Picks Nels – Erich Jarvis on scientists and public engagement Vincent – Polio type 1 in Africa Music on TWiEVO is performed by Trampled by Turtles Send your evolution quest ..read more
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