Interview with Sarah Christensen, Nordic Digital Director, Novartis Reuters Events: Pharma 2024 will run from 16-18 April 2024 at the International Barcelona Convention Center, Barcelona. The event will showcase ideas developed by a multitude of leading voices within the pharmaceutical industry as they seek to shape the future of the industry and how it engages with healthcare providers. Sarah Christensen, Nordic Digital Director at Novartis will participate in a panel discussion entitled “Unleash next-generation customer engagement models by harnessing generative AI” on the second day of t ..read more

HIGHLIGHTS What: With around 15% attrition the authors aimed to recruit at least 40 subjects. This study provides evidence for a highly positive correlation of maximum IOP during the mDTC and the WDT in open-angle glaucoma patients, including subjects on ocular hypotensive therapy, acquired using repeated, observer-masked data. This study demonstrated 93% agreement on eyes with IOP over 21 mmHg, a mean difference (bias) in maximum IOP of 0.82 mmHg (towards higher IOP in the WDT), and 95% limits of agreement within 4 mmHg. What this study adds This study provides observer-masked applanation and ..read more

HIGHLIGHTS What: The study aimed to enrol patients with mild to severe CKD mostly in stage G3: that means an estimated glomerular filtration rate (eGFR) of 30-60 mL/min/1.73m2 (KDIGO stage G3, A1-3) or an eGFR of > 60 mL/min/1.73m2 in the presence of overt albuminuria defined by a urine albumin creatinine ratio (UACR) of > 300 mg/g or equal amounts of proteinuria (KDIGO stage G1-2, A3). The main advantage of this study compared to most of the proteomic studies is the use of a validated ELISA for measurement of apoA-IV and the prospective assessment of cancer outcomes. Who: Barbara Koller ..read more

HIGHLIGHTS What: The authors aimed to investigate the prognostic value of the C-reactive protein to albumin ratio (CAR) for all-cause mortality in patients with chronic heart failure with reduced (HFrEF). To neurohormonal activation, circulating levels of proinflammatory cytokines 2 of 11 have been the main focus of interest for understanding HFrEF progression. To determine the main outcome of the study, either follow-up interviews or visiting outpatient clinics or hospital electronic databases were used. A receiver operating characteristic (ROC) curve analysis was conducted to determine the o ..read more

HIGHLIGHTS What: This research investigates the immunohistochemical expression of Perlecan by tumor cells in female breast and the correlation of such expression with the pathologic parameters of the tumors. By studying the relationship between the ER status and Perlecan expression, the study showed that higher expression was found in ER-positive cases. The authors examined Perlecan immunohistochemical expression in breast cancer cells which was found to be low in 41 cases (55.4%) and high in 33 cases (44.6%). Who: Asian Pac J Cancer et al. from the (UNIVERSITY) have published the Article: Imm ..read more

HIGHLIGHTS What: The aim of this research is to create a chemo-selective probe capable of analyzing samples on site with minimal or no prior sample pretreatment. The authors utilized a 24 full-factorial design in the CCD format to create mathematical models that would enable a quantitative assessment of sensor behavior under the influence of various parameters. The primary focus of this investigation composite full-factorial experimental design. To assess the suitability of the model, the authors conducted a Lack of Fit analysis, which should ideally yield an insignificant result for the model ..read more

HIGHLIGHTS What: The authors focus on the contribution of THs in repairing demyelinating lesions that are characteristic of MS, a chronic inflammatory disease that affects the entire CNS (brain and spinal cord). This study has for the first time precisely reported the cellular location of both transporters. Who: SVZ and collaborators from the University of Algarve, Portugal RMIT University, Australia have published the article: Thyroid hormone action in adult neurogliogenic niches: the known and unknown, in the Journal: (JOURNAL) Future: The expression of the TRa2 isoform should be better inve ..read more

HIGHLIGHTS What: The aim of this Article is to highlight potential areas for women where women are and can participate (in the road and construction sector labour market), by analyzing market and employment related trends and requirements (Umar et_al, 2018a). The study also looks briefly at demand-side determinants and found that local labour market conditions, such as whether relatively more people were employed in manufacturing and services rather than in agriculture, were associated with a reduced likelihood of labour market participation. Who: Asith Hettiarachchi from the Department of Eco ..read more

HIGHLIGHTS What: The authors characterize the trees T with γ× n( T )+l ( T )-s( T )+1 show that γ2oi ( T ) ≥ for any tree T with n( T ) ≥ 3. The authors show an interesting result, which is a consequence of Theorem 1. The authors give a new lower bound for the 2-outer-independent domination number of a tree (in function on the order, the number of support vertices and the number of leaves), and the authors provide a constructive characterization of the trees that satisfy equality in that bound. The authors show that the double outer-independent domination number is greater than the total outer ..read more

HIGHLIGHTS What: In the current study, the characterization of valuable biological activities of oryzalin-induced polyploid T. vulgaris essential oil has been acquired for the first time. Who: Neha Gupta from the DepartmentCzech University have published the research: Synthetic polyploidization induces enhanced phytochemical profile and biological activities in Thymus vulgaris L. essential oil, in the Journal: Scientific Reports Scientific Reports of 12/Nov/2023 SUMMARY Plant material acquisition Essential oil extraction Fresh aerial parts of T. vulgaris were obtained from tetraploid and diplo ..read more