Salience network connectivity is altered in 6-week-old infants at heightened likelihood for developing autism
Communications Biology
by Tawny Tsang, Shulamite A. Green, Janelle Liu, Katherine Lawrence, Shafali Jeste, Susan Y. Bookheimer, Mirella Dapretto
14h ago
Communications Biology, Published online: 22 April 2024; doi:10.1038/s42003-024-06016-9 Infants with heightened vs. lower likelihood of developing autism spectrum disorder exhibit different functional connectivity patterns in the salience network. These patterns predict sensory and social behaviors at 1 year of age ..read more
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Selective deforestation and exposure of African wildlife to bat-borne viruses
Communications Biology
by Pawel Fedurek, Caroline Asiimwe, Gregory K. Rice, Walter J. Akankwasa, Vernon Reynolds, Catherine Hobaiter, Robert Kityo, Geoffrey Muhanguzi, Klaus Zuberbühler, Catherine Crockford, Regina Z. Cer, Andrew J. Bennett, Jessica M. Rothman, Kimberly A. Bishop-Lilly, Tony L. Goldberg
14h ago
Communications Biology, Published online: 22 April 2024; doi:10.1038/s42003-024-06139-z A study in Uganda found that local extirpation of a mineral-rich tree species used in tobacco farming forced wildlife to obtain minerals by eating bat guano, in which 27 eukaryotic viruses were identified, including a novel betacoronavirus ..read more
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Single-cell T-cell receptor repertoire profiling in dogs
Communications Biology
by My H. Hoang, Zachary L. Skidmore, Hans Rindt, Shirley Chu, Bryan Fisk, Jennifer A. Foltz, Catrina Fronick, Robert Fulton, Mingyi Zhou, Nathan J. Bivens, Carol N. Reinero, Todd A. Fehniger, Malachi Griffith, Jeffrey N. Bryan, Obi L. Griffith
14h ago
Communications Biology, Published online: 22 April 2024; doi:10.1038/s42003-024-06174-w A single cell TCRseq method for dogs that robustly detects TCR expression suggests reannotation of some non-functional VJ genes between diverse between diverse repertoires of healthy dogs and expanded repertoires in malignancies ..read more
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Disulfiram treatment suppresses antibody-producing reactions by inhibiting macrophage activation and B cell pyrimidine metabolism
Communications Biology
by Weili Chen, Etsuko Toda, Kazuhiro Takeuchi, Yurika Sawa, Kyoko Wakamatsu, Naomi Kuwahara, Arimi Ishikawa, Yuri Igarashi, Mika Terasaki, Shinobu Kunugi, Yasuhiro Terasaki, Kazuhiko Yamada, Yuya Terashima, Akira Shimizu
14h ago
Communications Biology, Published online: 22 April 2024; doi:10.1038/s42003-024-06183-9 The FDA-approved drug disulfiram can inhibit B cells and infiltration of macrophages in a mouse model of heart transplantation ..read more
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Revealing the mechanisms of semantic satiation with deep learning models
Communications Biology
by Xinyu Zhang, Jing Lian, Zhaofei Yu, Huajin Tang, Dong Liang, Jizhao Liu, Jian K. Liu
14h ago
Communications Biology, Published online: 22 April 2024; doi:10.1038/s42003-024-06162-0 This study, utilizing deep learning to model semantic saturation, shows its tie to repetitive visual stimuli processing by the primary visual cortex, suggesting a bottom-up neurocognitive process ..read more
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Intranasal oxytocin suppresses seizure-like behaviors in a mouse model of NGLY1 deficiency
Communications Biology
by Yukimasa Makita, Makoto Asahina, Reiko Fujinawa, Hiroshi Yukitake, Tadashi Suzuki
14h ago
Communications Biology, Published online: 22 April 2024; doi:10.1038/s42003-024-06131-7 Epileptic seizure is one of the symptoms in patients with NGLY1 deficiency, a congenital disorder of deglycosylation. Here the authors show suppressive effects of oxytocin on seizure-like behaviors in a mouse model of NGLY1 deficiency ..read more
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Leukemia circulation kinetics revealed through blood exchange method
Communications Biology
by Alex B. Miller, Felicia H. Rodriguez, Adam Langenbucher, Lin Lin, Christina Bray, Sarah Duquette, Ye Zhang, Dan Goulet, Andrew A. Lane, David M. Weinstock, Michael T. Hemann, Scott R. Manalis
14h ago
Communications Biology, Published online: 20 April 2024; doi:10.1038/s42003-024-06181-x A blood exchange system reveals that leukemia cells clear faster in the blood than circulating tumor cells from solid tumors and that clearance rates can vary in response to tumor and treatment status ..read more
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Single-cell transcriptomics unveil profiles and interplay of immune subsets in rare autoimmune childhood Sjögren’s disease
Communications Biology
by Myung-Chul Kim, Umasankar De, Nicholas Borcherding, Lei Wang, Joon Paek, Indraneel Bhattacharyya, Qing Yu, Ryan Kolb, Theodore Drashansky, Akaluck Thatayatikom, Weizhou Zhang, Seunghee Cha
4d ago
Communications Biology, Published online: 19 April 2024; doi:10.1038/s42003-024-06124-6 This study maps the peripheral immune landscape of childhood Sjogren’s disease at single-cell level, providing immune and molecular characterizations that necessitate a better understanding in the etiology of the rare autoimmune disease ..read more
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Differences in diacylglycerol acyltransferases expression patterns and regulation cause distinct hepatic triglyceride deposition in fish
Communications Biology
by Xiaojun Xiang, Renlei Ji, Shangzhe Han, Xiang Xu, Si Zhu, Yongnan Li, Jianlong Du, Kangsen Mai, Qinghui Ai
4d ago
Communications Biology, Published online: 19 April 2024; doi:10.1038/s42003-024-06022-x Two diacylglycerol acyltransferases were shown to be differently regulated in large yellow croaker and rainbow trout. While DGAT1 is increased upon oleic acid treatment more in croaker than in trout, DGAT2 showed no significant expression difference ..read more
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Highly pathogenic avian influenza A(H5N1) virus in a common bottlenose dolphin (Tursiops truncatus) in Florida
Communications Biology
by Allison Murawski, Thomas Fabrizio, Robert Ossiboff, Christina Kackos, Trushar Jeevan, Jeremy C. Jones, Ahmed Kandeil, David Walker, Jasmine C. M. Turner, Christopher Patton, Elena A. Govorkova, Helena Hauck, Suzanna Mickey, Brittany Barbeau, Y. Reddy Bommineni, Mia Torchetti, Kristina Lantz, Lisa Kercher, Andrew B. Allison, Peter Vogel, Michael Walsh, Richard J. Webby
4d ago
Communications Biology, Published online: 18 April 2024; doi:10.1038/s42003-024-06173-x A case report of highly pathogenic avian influenza A H5N1 of clade 2.3.4.4b in the brain of a common bottlenose dolphin (Tursiops truncatus) from Florida, United States ..read more
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