Spectrum » CRISPR
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Spectrum » CRISPR
6M ago
This month’s Going on Trial newsletter explores a new tool for communicating with clinical trial participants and their families, among other drug development news.
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Spectrum » CRISPR
7M ago
The approach, which combines CRISPR with single-cell analyses of organoids, suggests that intermediate progenitor cells are especially vulnerable to mutations associated with autism.
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Spectrum » CRISPR
9M ago
The newfound DNA-cutting enzyme, called Fanzor, can be programmed to edit the human genome and could prove easier to deliver to cells than current CRISPR tools.
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Spectrum » CRISPR
10M ago
The discovery could help clinicians diagnose children who carry mutations in the gene, called SCN2A, and gauge their responses to potential therapies.
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Spectrum » CRISPR
10M ago
The gene-editing advances make it easier to target specific tissues in mice and detect off-target effects.
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Spectrum » CRISPR
11M ago
The approach provides an “off-the-shelf” way for researchers to compare oxytocin function across species, the team says.
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Spectrum » CRISPR
1y ago
CRISPR-edited prairie voles that lack receptors for the so-called “social hormone” still bond with their mate and pups, raising questions about the molecule’s role.
The post ‘Mind-blowing’ study upends conventional wisdom on oxytocin appeared first on Spectrum | Autism Research News ..read more
Spectrum » CRISPR
1y ago
The model enables the study of autism-linked genes at the earliest stages of neural development.
The post ‘Assembloids’ lay bare autism-linked genes that hamper neuron development appeared first on Spectrum | Autism Research News ..read more
Spectrum » CRISPR
1y ago
The new tool may help researchers reconstruct the sequence of biological events that underlie development.
The post ‘Retro-Cascorder’ tracks gene-expression timing appeared first on Spectrum | Autism Research News ..read more
Spectrum » CRISPR
2y ago
Strategies to replace or compensate for mutated copies of the TCF4 gene could lead to treatments for this profound form of autism, a new study suggests.
The post Organoids test gene therapies for Pitt-Hopkins syndrome appeared first on Spectrum | Autism Research News ..read more