Philip B James Medical Gas Research 2023 13(4):219-219 ..read more

Joël Lemaire, Michel Heninger, Essyllt Louarn, Ira Katz, Renaud Tissier, Matthieu Chalopin, Géraldine Farjot, Aude Milet Medical Gas Research 2023 13(4):208-211 The noble gas argon has demonstrated biological activity that may prove useful as a medical intervention. Pharmacokinetics, the disposition of the drug molecule in the body through time, is fundamental necessary knowledge to drug discovery, development and even post-marketing. The fundamental measurement in pharmacokinetic studies is blood concentration of the molecule (and its metabolites) of interest. While a phys ..read more

He Li, Hong-Yu Ma, Wei-Long Hua, Yong-Xin Zhang, Lei Zhang, Peng-Fei Xing, Peng-Fei Yang, Jian-Min Liu Medical Gas Research 2023 13(4):212-218 The medical use of molecular hydrogen, including hydrogen-rich water and hydrogen gas, has been extensively explored since 2007. This article aimed to demonstrate the trend in medical research on molecular hydrogen. A total of 1126 publications on hydrogen therapy were retrieved from the PubMed database until July 30, 2021. From 2007 to 2020, the number of publications in this field had been on an upward trend. Medical Gas Research, Scientific Report ..read more

Celal Yavuz, Oguz Karahan, Özgür Akkaya Medical Gas Research 2023 13(4):198-201 Hyperbaric oxygen (HBO) treatment aims to restore tissue oxygenation by inhaling 100% oxygen in pressure rooms. Although beneficial effects have been reported with regard to re-oxygenated ischemic tissues, conflicting findings have been presented concerning the paradoxical tissue response following reperfusion and/or the different responses of non-ischemic normal tissues to increased oxygen exposure. The present study sought to experimentally investigate the impact of continuous HBO treatments o ..read more

Ashini R Dias, Constantine Bitsaktsis, Daniella Emdin, Lisa Bosman, Andre Hugo Smith, Zaher Merhi Medical Gas Research 2023 13(4):202-207 There are limited treatment options for women with severely diminished ovarian reserve (DOR) who experience repeatedly failed in vitro fertilization (IVF) cycles and with persistently thin endometrial lining thickness (EMT) during frozen embryo transfer cycles. Therefore, a large majority of patients resort to using donor oocytes and gestational carriers. Data from existing animal and human studies suggest that ozone sauna therapy (OST) and pulsed electrom ..read more

Susheela Taxak, Mohini Gupta, Renu Bala, Vasudha Govil, Anushmita Lallar Medical Gas Research 2023 13(4):187-191 A primary concern for anesthesiologists is the maintenance of oxygenation during general anesthesia. Extending the safe apnea time, which is the time from the onset of apnea until the oxygen saturation concentration reaches 90% or less, increases the margin of safety with tracheal intubation. Preoxygenation before anesthetic induction has been a widely accepted manoeuver to increase oxygen reserves and hence delay the onset of arterial desaturation during apnea. This study aimed t ..read more

Burcu Namazoğlu, Merve Aksoy, Betül Memiş-Özgül, Firdevs Tulga-Öz Medical Gas Research 2023 13(4):192-197 Oral biofilm formation is the main reason for both caries progression and soft tissue diseases. Preventing the formation and promotion of biofilm has been known as the first attempt to prevent the development of caries and soft tissue problems in the oral cavity. The present study aimed to assess the effect of ozone and its combined use with chlorhexidine (CHX) and fluoride on the complex biofilm formation of pediatric patients under ..read more

Hesameddin Modir, Rasol Jafarirismani, Amir Almasi-Hashiani, Kiana Shamaii Medical Gas Research 2023 13(4):181-186 The authors sought to quantify the clinical impacts of granisetron, ketamine, dexmedetomidine, and lidocaine combined with fentanyl, for procedural sedation and analgesia in cystoscopy and for bladder catheter tolerance. This double-blind trial recruited four stratified blocked randomized eligible groups of patients (n = 120) formerly identified as needing cystoscopy, each receiving one of the above four anesthetic agents. Dexmedetomidine-sedated subjects experienced less pain f ..read more

Medical Gas Research 2023 13(4):180-180 ..read more

Maria Emilia Gadelha Serra, José Baeza-Noci, Carmen Verônica Mendes Abdala, Marilia Moura Luvisotto, Charise Dallazem Bertol, Ana Paula Anzolin Medical Gas Research 2023 13(4):172-180 Ozone therapy (OT), a medical procedure, has been showing good results during the coronavirus disease (COVID-19). We aimed to build an evidence and gaps map (EGM) of OT in the COVID-19 ranking the articles found according to levels of evidence and outcomes. The EGM brings bubbles of different sizes and different colors according to the articles. The OT intervention used was major or minor auto ..read more