Positive trial results for PharmNovo’s pain management drug
Pf Media Magazine
by Joanna Harvey
3h ago
PharmNovo’s trial from Phase I of its neuropathic pain drug candidate, PN6047, has given positive results in the feedback. The trial demonstrates the safety and tolerability of PN6047, underscoring its potential as an innovative option in pain management. Furthermore, PN6047 was completely devoid of adverse events typically associated with conventional opioids like oxycodone and morphine, such as respiratory depression, constipation, itching, or untoward effects following withdrawal symptoms. This validates the unique preclinical profile of PN6047, which shows that it acts very selectively on ..read more
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Research uncovers how to target dormant breast cancer cells and prevent relapse
Pf Media Magazine
by Emma Cooper
3h ago
Scientists have discovered how breast cancer cells can ‘hibernate’ to avoid treatment and ‘wake up’ years later – causing a relapse that is more difficult to treat. Their early stage research, published in the journal Cancer Discovery, reveals the role of ‘epigenetics’ in controlling how cancer cells can become dormant – and suggests a strategy to target it before the cells wake up. Epigenetic changes alter how your body reads your DNA, without changing the DNA code itself. Patients with oestrogen receptor positive (ER+) breast cancer – which make up 80% of all breast cancers – have ..read more
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Landmark NHS deal to combat antimicrobial resistance
Pf Media Magazine
by Joanna Harvey
3h ago
Mid Yorkshire Teaching NHS Trust has approved the commercial adoption of Ondine’s light-activated antimicrobial, Steriwave®, to help tackle antimicrobial resistance. The approval will see the use of Steriwave® expanded across hip and knee surgery patients at Pontefract and Pinderfields NHS Hospitals to reduce the incidence of surgical site infections (SSIs). Steriwave is a light-activated antimicrobial that uses a specific wavelength of red light to destroy pathogens that colonise the nose and can spread to cause harmful infections. Unlike traditional antibiotics, Steriwave is immediately effe ..read more
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HCP engagement solutions – being present isn’t enough
Pf Media Magazine
by Emma Morriss
1w ago
Have you invested in digital engagement of HCPs? Are you preparing for the future? When it comes to engaging healthcare professionals online, being present isn’t enough. You need strategic engagement solutions to meet their needs across multiple channels. The pharmaceutical industry has significantly increased its digital engagement presence – websites, education portals, virtual events, podcasts, there’s no shortage of content available to share with customers and support their education and patients. But what may have been a scattergun approach, activity by activity and need by nee ..read more
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AI tool set to make drug discovery 100 times faster
Pf Media Magazine
by Joanna Harvey
1w ago
bioXcelerate, a health data science division of Optima Partners Limited, have launched a new AI tool, which is set to accelerate the process for identifying and developing new drugs. The tool, known as PleioGraph, can analyse complex medical data 100 times faster than existing state-of-the-art methods, used to detect biological networks which explain disease risk and inform drug discovery. The technology uses bioXcelerate’s own machine learning algorithms to sweep huge amounts of biological data to help drug developers identify the genes, proteins and cells that interact with each other to cau ..read more
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Roquette acquires IFF Pharma Solutions
Pf Media Magazine
by Joanna Harvey
1w ago
Roquette, a global leader in plant-based ingredients and pharmaceutical excipients, has acquired IFF Pharma Solutions, a worldwide producer of excipients for oral dosage solutions, to reinforce its position as a major partner to the pharmaceutical industry. The combination of the two complementary businesses will rebalance the company’s portfolio around the two pillars of health and nutrition. It will expand its pharma product range and significantly accelerate Roquette’s growth. The acquisition enhances Roquette’s US footprint, and significantly expands its industry-leading formulation capabi ..read more
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Almirall expands pipeline to rare dermatological diseases
Pharmafield Magazine
by Joanna Harvey
2w ago
Almirall has signed a licensing agreement with Eloxx Pharmaceuticals to acquire ZKN-013 – the first asset in Almirall’s pipeline focused on rare diseases. Under the agreement, Almirall obtains global rights to develop and commercialize ZKN-013, including for the use in orphan dermatological diseases. ZKN-013 is a potentially promising oral, nonsense mutation readthrough drug, which enables the host cells to produce functional proteins which counteract the root cause of these rare dermatological and potentially other diseases. The drug candidate is expected to shortly enter into Phase I develop ..read more
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SMC accepts AbbVie’s new Parkinson’s drug within NHS Scotland
Pharmafield Magazine
by Joanna Harvey
2w ago
The Scottish Medicines Consortium (SMC) has accepted AbbVie’s new Produodopa® (foslevodopa-foscarbidopa) for restricted use within NHS Scotland for the treatment of advanced levodopa-responsive Parkinson’s disease. The SMC has restricted its use to patients with advanced Parkinson’s disease who are not eligible for deep brain stimulation (DBS). Foslevodopa-foscarbidopa offers an additional treatment choice in the therapeutic class of dopa and dopaderivatives for this indication. Another medicine within this therapeutic class has been accepted via the orphan medicine process for this indication ..read more
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Pf Awards 2024 Winners Announced
Pharmafield Magazine
by Joanna Harvey
2w ago
The Pf Awards 2024 winners were announced on Thursday 7 March, celebrating the 24th year of recognising outstanding achievements in the pharmaceutical industry.   Paul Sinha, known famously as The Sinnerman on ITV’s The Chase, bought a wealth of humour to the ceremony, which this year was in partnership with Parkinsons UK.   The evening’s celebrations were opened by our 2023 Outstanding Individual Performer Winners, Adele Marshall and Sarah Valente-Smith, from MSD. The duo touched on how their win boosted their confidence and reinforced that living their values and challeng ..read more
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Akari Therapeutics merge with Peak Bio
Pharmafield Magazine
by Joanna Harvey
2w ago
Akari Therapeutics have merged with Peak Bio, with an expanded pipeline that contains multiple compelling assets, spanning early and late development stages. An assessment of the pipeline is planned, including program prioritisation, updated timelines, near-term value creation opportunities, and other considerations. The combined entity will operate as Akari Therapeutics, Plc. Key highlights of the merger include a robust ADC toolkit with novel payload and linker technologies, multiple compelling assets spanning early and late stages, strategic focus to emphasise business development and licen ..read more
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