CRISPR-based gene editing shows promise in treating rare form of blindness
News-Medical.Net | Drug Trial News
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2d ago
About 79% of clinical trial participants experienced measurable improvement after receiving experimental, CRISPR-based gene editing that is designed to fix a rare form of blindness, according to a paper published in the New England Journal of Medicine ..read more
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MedStar Washington Hospital Center enrolls first U.S. patient in gene-editing therapy trial for heart disease
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2d ago
The first U.S. heart patient involved in a study for a new gene-editing therapy directly infused inside the body has successfully been enrolled at MedStar Washington Hospital Center ..read more
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Plant-based medication may be an effective therapy to help people quit vaping
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2d ago
Eleven million U.S. adults use e-cigarettes to vape nicotine, and about half of them say that they want to stop, but many have trouble doing so because nicotine is an addictive drug ..read more
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Measles and rubella vaccine delivered via microarray patch shows promising results
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1w ago
The phase 1/2 randomized trial compared results from the measles and rubella vaccine delivered by a microarray patch, a small sticking plaster-like device with an array of microscopic projections that painlessly penetrate the skin and deliver the vaccine, or by conventional injection with a needle and syringe ..read more
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Single dose of malaria monoclonal antibody 77% effective in children, trial in Mali shows
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1w ago
One injected dose of an experimental malaria monoclonal antibody was 77% effective against malaria disease in children in Mali during the country's six-month malaria season, according to the results of a mid-stage clinical trial ..read more
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First UK real-world study shows promise for sacituzumab govitecan in metastatic breast cancer
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1w ago
The real-world safety and efficacy of sacituzumab govitecan (SG) against metastatic triple-negative breast cancer ..read more
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CASGEVY gene therapy eliminates vaso-occlusive crises in sickle cell patients
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2w ago
In a landmark study, an international consortium led by researchers at Children's Hospital of Philadelphia (CHOP) published the final results of a key clinical trial of the gene therapy CASGEVY (exagamglogene autotemcel) for the treatment of sickle cell disease in patients 12 years and older with recurrent vaso-occlusive crises (VOCs ..read more
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Novel immunotherapy shows promise for high-risk sarcomas: HEROS 2.0 trial results published
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2w ago
Researchers at Texas Children’s Cancer Center and the Center for Cell and Gene Therapy at Baylor College of Medicine, Texas Children’s Hospital and Houston Methodist published results of a phase I clinical trial of a novel immunotherapy for high-risk sarcomas in the journal Nature Cancer ..read more
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WOO Network trials investigate innovative treatments for liver, head and neck cancers
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2w ago
A new round of clinical trials supported by the Ontario Institute for Cancer Research (OICR) will harness a unique opportunity to test some of the newest treatment strategies for a range of different cancers ..read more
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Phase 3 trial shows overall survival benefit from adjuvant therapy in kidney cancer patients
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3w ago
For the first time in fifty years, results from a phase 3 randomized, placebo-controlled trial have shown an overall survival benefit from an adjuvant therapy in patients with kidney cancer ..read more
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