This case report describes a diagnosis of conjunctival Kaposi sarcoma in a patient recently diagnosed with HIV infection and taking highly active antiretroviral therapy ..read more

This case report discusses a diagnosis of rhino-orbital-cerebral mucormycosis in a man aged 61 years who presented with vision loss, ophthalmoplegia, and ptosis ..read more

This case report describes a diagnosis of iridodialysis in an 11-year-old boy who presented with decreased vision and inflammation after direct blunt trauma to the left eye ..read more

To the Editor In their analysis of data from the 2021 National Survey of Children’s Health, Oke et al demonstrated that children aged 6 to 18 years from historically marginalized racial and ethnic groups, low-income households, and non–English language speakers were less likely to receive vision screening and less likely to establish care with an eye specialist if they were screened ..read more

This cohort study estimates the prevalence of inherited retinal diseases in the Israeli population ..read more

To the Editor We read with great interest the article by Sutton and colleagues investigating the association between acetylcholinesterase inhibitors (AChEIs) and the incidence of age-related macular degeneration (AMD) among US veterans with Alzheimer disease (AD). The study shows a slight decrease in the incidence of AMD in patients with AD receiving AChEIs. While this study sheds light on the exciting therapeutic potential of AChEIs, some methodological issues should be assessed ..read more

This secondary analysis of the ASPREE randomized clinical trial was conducted to evaluate the effect of long-term low-dose aspirin on age-related macular degeneration ..read more

This comparative effectiveness research study assesses the rate of tissue loss in ultrathin Descemet stripping automated endothelial keratoplasty grafts vs descemet membrane endothelial keratoplasty grafts during eye bank processing ..read more

In Reply I very much appreciate the response by Wykoff and colleagues to my Viewpoint on pegcetacoplan (Syfovre). They appropriately highlight a prior US Food and Drug Administration (FDA) disclosure that was not available at the time of writing the Viewpoint. Review of this FDA report reveals potential concerns with the statistical analyses that were used, specifically, the effect of sham “pooling” on the final results. The findings summarized below bring into question the appropriateness of pooling the sham treatment arms. Notably, without sham pooling, the treatment effect in DERBY was not ..read more

This Clinical Evidence Synopsis summarizes systematic reviews regarding pharmacologic interventions for proliferative vitreoretinopathy ..read more