Scientists Gain Crucial Insights into Traffic Cop Function of Gene Expression Protein
Dr. Brian David Strahl | Chromatin Biology & Epigenetics at UNC-Chapel Hill
by drbrianstrahl
3y ago
UNC scientists led by Brian Strahl, PhD, and Raghuvar Dronamraju, PhD, uncovered a key regulatory step in gene expression that may be a significant factor in cancers and other major diseases. Media contact: Mark Derewicz, 984-974-1915, mark.derewicz@unchealth.unc.eud December 18, 2018 CHAPEL HILL, NC – Scientists at the UNC School of Medicine have discovered a crucial quality-control mechanism inside cells that, when it fails, might contribute to major diseases including cancers. The discovery, published in Cell Reports, concerns the process of gene transcription or gene express ..read more
Visit website
UNC scientists discover new gene expression mechanism with possible role in human disease
Dr. Brian David Strahl | Chromatin Biology & Epigenetics at UNC-Chapel Hill
by drbrianstrahl
3y ago
UNC School of Medicine researchers, led by Brian Strahl, PhD, found surprising role for a protein called Spt6, which is crucial to the maintenance of proper messenger RNA levels in cells, a discovery that opens new research avenues and suggests a target for basic understanding, diagnosis, and treatment of human diseases. Media contact: Mark Derewicz, 984-974-1915, mark.derewicz@unchealth.unc.edu June 21, 2018 CHAPEL HILL, NC –When cells grow and divide to ensure a biological function – such as a properly working organ – DNA must be unwound from its typical tightly packed form and copied into R ..read more
Visit website
Dr. Brian David Strahl Awarded NIGMS Outstanding Investigator Grant
Dr. Brian David Strahl | Chromatin Biology & Epigenetics at UNC-Chapel Hill
by drbrianstrahl
3y ago
  Brian David Strahl, Professor of Biochemistry & Biophysics and Oliver Smithies Investigator, has been awarded a 5-Year Outstanding Investigator R35 Maximizing Investigators’ Research Award (MIRA) for his research on gene expression and chromatin regulation. The goal of the MIRA award is to increase the efficiency of NIGMS funding by providing investigators with greater stability and flexibility to enhance scientific productivity and the chances for important breakthroughs. Brian D. Strahl is a Professor & Vice-Chair of the Department of Biochemistry & ..read more
Visit website
Yeh and Strahl named Smithies Investigators
Dr. Brian David Strahl | Chromatin Biology & Epigenetics at UNC-Chapel Hill
by drbrianstrahl
3y ago
The UNC School of Medicine selected professors from the departments of surgery, and biochemistry and biophysics for the annual award in honor of Oliver Smithies, UNC’s first Nobel Prize winner. Jen Jen Yeh, MD, and Brian Strahl, PhD January 31, 2018 The UNC School of Medicine selected Jen Jen Yeh, MD, professor and vice chair of research for the department of surgery, and Brian Strahl, PhD, professor and vice chair of the department of biochemistry and biophysics, as Smithies Investigators, an annual award to honor senior faculty members who have made significant research contributions and ..read more
Visit website
Researchers show how a cancer gene protects genome organization
Dr. Brian David Strahl | Chromatin Biology & Epigenetics at UNC-Chapel Hill
by drbrianstrahl
3y ago
UNC study uncovers crucial function of a yeast enzyme Set2 whose well-conserved human counterpart is often mutated in cancers, especially kidney cancer. Media Contact: Mark Derewicz, 919-923-0959, mark.derewicz@unchealth.unc.edu June 13, 2017 CHAPEL HILL, NC – UNC School of Medicine researchers have cracked a long-standing mystery about an important enzyme found in virtually all organisms other than bacteria. The basic science finding may have implications for understanding cancer development and how to halt it. Researchers have known that the enzyme Set2 is important for transcribing genes ..read more
Visit website
New Strahl lab photo of 2017!
Dr. Brian David Strahl | Chromatin Biology & Epigenetics at UNC-Chapel Hill
by drbrianstrahl
3y ago
..read more
Visit website
New antibody portal bolsters biomedical research reliability
Dr. Brian David Strahl | Chromatin Biology & Epigenetics at UNC-Chapel Hill
by drbrianstrahl
3y ago
UNC’s Brian Strahl, PhD, and Van Andel Research Institute’s Scott Rothbart, PhD, create a robust online interactive database to address science’s ‘antibody crisis’. July 23, 2015 CHAPEL HILL, NC – For years, a crisis has been brewing in molecular biology. The problem is that antibodies – research tools used to identify key proteins at work in a cell – aren’t always what they seem. Unreliable antibodies have led to numerous instances of false findings, failed experiments, and wasted money and samples. Enter the Histone Antibody Specificity Database (www.histoneantibodies.com), a newly launched ..read more
Visit website
UNC Program in Chromatin and Epigenetics Launches
Dr. Brian David Strahl | Chromatin Biology & Epigenetics at UNC-Chapel Hill
by drbrianstrahl
3y ago
UNC has launched a new program that aims to address the fundamental gaps in knowledge surrounding epigenetic regulation, with a long-term goal of developing novel therapeutic approaches towards treating human disease. The program is centered around a highly collaborative and team science environment that has a dedicated goal of solving fundamental and challenging problems in chromatin biology – with an emphasis on developing novel approaches towards treating human disease. The large number of research faculty at UNC specializing in different areas of epigenetic research are optimally positione ..read more
Visit website
Epigenetic Breakthrough: A first of its kind tool to study the histone code
Dr. Brian David Strahl | Chromatin Biology & Epigenetics at UNC-Chapel Hill
by drbrianstrahl
3y ago
Scientists from UNC-Chapel Hill have created a new way to investigate epigenetic mechanisms important in diseases ranging from Alzheimer’s to cancers. Robert Duronio, PhD; Daniel McKay, PhD; Greg Matera, PhD; Brian Strahl, PhD. CHAPEL HILL, NC –University of North Carolina scientists have created a new research tool, based on the fruit fly, to help crack the histone code.  This research tool can be used to better understand the function of histone proteins, which play critical roles in the regulation of gene expression in animals and plants. This work, published in the journal Development ..read more
Visit website
All the Cell’s a Stage
Dr. Brian David Strahl | Chromatin Biology & Epigenetics at UNC-Chapel Hill
by drbrianstrahl
3y ago
Brian Strahl, PhD, and his band of biochemists unravel the complicated mysteries of the epigenetic code to find a culprit in cancer development. By Mark Derewicz Every single human cell contains every single human gene.  But depending on the cell, only some of these genes need to be expressed or “turned on.” For instance, a heart cell has all the genes needed for, say, proper kidney function. But that heart cell won’t express those genes. In a heart cell, those genes are “turned off.” When one of these “wrong” genes is turned on by mistake, the result can be rampant cell growth – cancer ..read more
Visit website

Follow Dr. Brian David Strahl | Chromatin Biology & Epigenetics at UNC-Chapel Hill on FeedSpot

Continue with Google
Continue with Apple
OR