Microneedle Bandage for Hemostatic Control
Medgadget
by Conn Hastings
6d ago
Scientists at Penn State have developed a microneedle bandage that can rapidly stop bleeding. Uncontrolled bleeding following a traumatic injury is a major cause of death in the young, and developing new medical technologies that can rapidly stop bleeding would be highly beneficial. This bandage contains an array of biodegradable and biocompatible microneedles made using a gelatin methacryloyl biomaterial. The device also contains silicate nanoplatelets that give it its hemostatic properties, and the needle structure increases the surface area for blood contact and helps to bind the bandage t ..read more
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Flexible Sensors Detect Heavy Metals in Sweat
Medgadget
by Conn Hastings
6d ago
Researchers at the University of São Paulo in Brazil, along with collaborators in Germany and Sweden, have developed a flexible sensor that can detect heavy metals in sweat, an easily obtainable bodily fluid. Heavy metals, such as lead or cadmium, can cause serious toxicity if they accumulate in the body, but detecting the concentration of such metals in biological samples requires expensive laboratory equipment and skilled staff. To address this, these researchers have created a flexible sensor that is easy to use and which can detect metals in sweat samples before transmitting the results t ..read more
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Ultrasound Tornado Rapidly Disrupts Blood Clots
Medgadget
by Conn Hastings
1w ago
A team of researchers at North Carolina State University have developed an ultrasound transducer that can disrupt blood clots in the brain quickly by creating an ultrasound vortex or ‘tornado’. The transducer is designed to be housed in a catheter that can be advanced through the vasculature until it reaches the site of a blood clot in the brain, such as those that occur in cases of cerebral venous sinus thrombosis. The technique can disrupt clots more quickly than conventional forward-facing ultrasounds, as the vortex wave creates shear stress that helps to break the clot into pieces. The ap ..read more
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Nanopore Sensor to Study Protein Aggregation in Neurodegeneration
Medgadget
by Conn Hastings
1w ago
Researchers at the University of Arkansas have developed a nanopore sensor to study the aggregation of tau and tubulin protein molecules. These proteins, and specifically their aggregation in the brain, are implicated in neurodegenerative diseases such as Parkinson’s and Alzheimer’s. This nanopore technology aims to allow researchers to study the effects of different environmental conditions, including pH, salt concentration, and temperature, on how these proteins aggregate. The researchers hope that their advancement can help to understand the underlying mechanisms of neurodegenerative disea ..read more
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Smart Walking Stick for Visually Impaired People
Medgadget
by Conn Hastings
1w ago
Researchers at the University of Colorado at Boulder have developed a smart walking stick that can assist blind or visually impaired people to navigate their environment, from grocery shopping to finding a seat in a busy café. The system employs cameras to visualize the environment and items within it, such as products in a supermarket, and uses AI to identify objects and provide guidance for the user. The stick can provide verbal and haptic prompts to help the user to move closer to a desired product on a supermarket shelf, for example. The researchers hope that the technology will assist th ..read more
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Balance Boards to Stay Active in the Offfice: Interview with Joel Heath, CEO of FluidStance 
Medgadget
by Alice Ferng
2w ago
Fun and durable, the FluidStance balance board deck can be found at many offices these days as working professionals with desk jobs look for ways to stay active and healthy. Long hours slumped over at a desk means that your muscles remain inactive for long periods of time – a running hypothesis is that long periods of inactivity lead to issues with glucose regulation, as muscles cease their regular glucose uptake and the body adapts to a sedentary lifestyle.  FluidStance’s balance board, Level, provides an engaging alternative to this by forcing your body to engage different muscles to b ..read more
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Biobots Use Optogenetic Muscle Actuators for Movement
Medgadget
by Conn Hastings
2w ago
Researchers at the University of Illinois at Urbana-Champaign have developed centimeter-scale biobots that combine soft materials, mouse muscle tissue, and wireless electronic components. The tiny devices can be controlled remotely through optogenetics. The muscle within the devices forms an optogenetic actuator and creates movement when exposed to light. The researchers can control this movement remotely by activating on-board micro-LEDs wirelessly, which then stimulate the muscle actuators to propel the biobot. The technology could be used in the future to perform tasks within the body, suc ..read more
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Hydrogel Scaffold Makes a Living Electrode
Medgadget
by Conn Hastings
2w ago
A team of researchers at the Harvard Wyss Institute have developed a soft, hydrogel scaffold that can function as a living electrode for brain-computer interface applications. The researchers used electrically conductive materials and created a porous and flexible scaffold using a freeze-drying process. They then seeded the scaffold with human neural progenitor cells (NPCs) and cultured the scaffolds for extended periods, prompting the cells to differentiate into a variety of neurons and astrocytes. The researchers hope that the resulting ‘living electrode’ could be useful for brain-computer i ..read more
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Bioprinted Eye Tissue to Study Retinal Diseases
Medgadget
by Conn Hastings
1M ago
Researchers at the National Eye Institute, which is part of the National Institutes of Health, have created a method to 3D bioprint eye tissue that forms the outer blood-retina barrier. This tissue supports the photoreceptors in the retina and is implicated in the initiation of age-related macular degeneration. The outer blood-retina barrier is the interface of the retina and the choroid, including Bruch’s membrane and the choriocapillaris. Image credit: National Eye Institute. The researchers combined different cell types, which are primarily derived from patient stem cells, in a hydrogel ca ..read more
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Point-Of-Care Biosensor to Detect Oral Cancer
Medgadget
by Conn Hastings
1M ago
Researchers at the University of Florida have created a point-of-care biosensor that can rapidly detect a biomarker for oral cancer. The device uses test strips, such as those used in blood glucose tests, to spot cell proliferation regulating inhibitor of protein phosphatase 2A (CIP2A), a protein biomarker that can reveal the presence of oral cancer. The device requires a liquid sample that is introduced to the end of the test strip, where it runs into channels that contain antibody-covered electrodes. The antibodies are specific for CIP2A, and antibody binding changes the electrical signal t ..read more
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