Nutrient, non-nutrient, antioxidant activity, and Fourier Transform Infrared analysis of Kenyan indigenous edible leafy vegetables from Launaea cornuta (Hochst Ex Oliv and Hiern)
African Journals Online | African Health Sciences
by Onyancha Jared Misonge , Moriasi Gervason Apiri , Mandela Elias Nelson
3M ago
Background: Launaea cornuta is a vegetable with therapeutic advantage for human diseases. Objective: Evaluate nutritive and non-nutritive components, antioxidant activity, and Fourier transform infrared spectroscopy profile of L. cornuta leaves. Methods: Proximate, nutri, non-nutrient, percentage phenolic, flavonoid, alkaloid, and saponin contents were investigated using standard procedures. Total phenolic and flavonoids of the extracts were determined spectroscopically. Antioxidant activity and functional groups in the extracts were characterised by 2.2- diphenyl-2-picryl-hydrazyl radical and ..read more
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Application of joint modelling on the determinants of TB Status and CD4 cell count among antiretroviral therapy attendants in Gondar teaching referral hospital, Gonder, Ethiopia
African Journals Online | African Health Sciences
by Gebre Kindu Kebede , Hussen Nuru Mohammed
3M ago
Abstract Background: East African regions were highly affected by tuberculosis and the human immunodeficiency virus. The main objective was to identifying the associated factors with tuberculosis and CD4 cell count of patients in Gonder teaching referral hospital, Gonder, Ethiopia. Methods: A retrospective cohort study was conducted on AIDS patients from 1st January 2018 - to 30th January 2020. This study used joint mixed model, and individual profile plot to identify factors and the changeability inside and between patients respectively. Results: The mean with a standard deviation of weight a ..read more
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Evaluation of the anatomical locations and sizes of uterine fibroids from ultrasound examination in Ghana
African Journals Online | African Health Sciences
by Edzie Emmanuel Kobina Mesi , Dzefi-Tettey Klenam , Brakohiapa Edmund Kwakye , Gorleku Philip Narteh , Aidoo Eric , Amoah Stephen Kwaku , Asiamah Samuel , Quarshie Frank , Nimo Obed , Raj Amrit , Kpobi Joshua Mensah , Boadi Evans , Edzie Richard Ato , Turkson Veronica , Kusodzi Henry , Asemah Abdul Raman
3M ago
Background: Uterine fibroids locations and sizes, have significant influences on the quality of life of women especially pregnant women and on live birth rate. Objectives: To determine the anatomical locations and sizes of uterine fibroids and assess any possible associations with age groups. Methods: This retrospective study reviewed the locations and sizes of a total of 3,542 patients who were ultrasonographically diagnosed with uterine fibroids from January 2019 to December 2021. The obtained data were analysed using GNU PSPP, and Python on Jupyter Notebook with statistical significance lev ..read more
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Maternal inherited thrombophilia and recurrent pregnancy loss: a Tunisian study and review of the literature
African Journals Online | African Health Sciences
by Frikha Rim , Turki Fatma , Abdelmoula Nouha , Rebai Tarek
3M ago
Background: Inherited thrombophilia, mainly the Factor V Leiden (FVL) and Prothrombin mutation (PTM) are the most risk factors for venous thrombosis especially during pregnancy and was strongly associated with recurrent pregnancy loss (RPL), a devastating reproductive problem that affects more than 1% of couples who are trying to conceive. The frequencies also the correlation among these polymorphisms and RPL have been reported controversially in various populations. Objectives: In this study we evaluated the presence inherited thrombophilia amongst 35 Tunisian women with more than 2 miscarria ..read more
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The immune-modulatory role of MSCs exerted by PI3K/AKT signaling pathway in kidney tissue after cyclophosphamide
African Journals Online | African Health Sciences
by Mohamed Saad eldien Heba , Jayed Mohammed Alenzi , Roshdy Ahmad Ahmad
3M ago
Background: Cyclophosphamide (CP) is one of the most effective immunosuppressive agents. To understand the mechanisms used by the CP and MSCs in the kidney, we investigated their effects on some pathways. Experimental animals and methods: 4 groups of female rats were used. GI: was the normal control group treated with saline solution. Groups G II, G III, and G IV were treated with CP. G I and G II groups were sacrificed on the fourth day after treatment., G III (Auto healing group) was left without treatment after the CP injection for six days. The G IV group was treated with MSCs on the fourt ..read more
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Frequency of domestic violence in pregnancy and its adverse maternal outcomes among Pakistani women
African Journals Online | African Health Sciences
by Shahmir Hussain Sana , Shafaq Makhdoom , Samia Husain , Aruna Hira , Khadija Bano , Haleema Yasmin
3M ago
Objective: To determine the frequency of domestic violence in pregnancy and its adverse maternal outcomes among Pakistani women. Material and methods: This was a prospective descriptive longitudinal study conducted at the Department of Obstetrics & Gynecology of Jinnah Postgraduate Medical Center, Karachi from October 2021 to March 2022. The questionnaire was filled during an interview. First part included demographic profile, second part comprised of 5 items with ‘yes’ or ‘no’ options. Any positive answer meant woman was subjected to abuse. Adverse maternal outcome was also assessed. Resu ..read more
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A plausible hypothesis for the higher Covid-19 mortality in Brazil
African Journals Online | African Health Sciences
by Silva Heslley Machado
3M ago
Brazil has high Covid-19 mortality rates, especially among those patients who are intubated. It is hypothetically considered that these rates may be related to the abusive use of medicines by the population. These drugs without scientific evidence are indicated by President Bolsonaro and his supporters but are also prescribed by doctors who follow this line. The text draws attention to the risks of this phenomenon ..read more
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Prevalence and determinants of poor glycaemic control in individuals aged between 18-60 years, at a regional hospital in KwaZulu-Natal Province, South Africa- a cross sectional study
African Journals Online | African Health Sciences
by Zimu Lindelwa , Mahomed Ozayr
3M ago
Background: Achieving optimal blood glucose control is imperative for preventing diabetes related complications and negative socio-economic consequences associated with them. Objectives: The aim of the study was to determine the prevalence and determinants of poor glycaemic control amongst type II diabetic outpatients presenting at a regional semi-rural hospital in eThekwini district, Kwa-Zulu Natal. Methods: An observational, analytic cross-sectional study was conducted amongst 384 systematically sampled type 2 diabetes patients. Data were collected by an interviewer administered questionnair ..read more
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Preferred techniques of hair harvest for medical testing among adult pulmonary TB patients
African Journals Online | African Health Sciences
by Muzanyi Grace , Mafigiri David K , Salata Robert , Joloba Moses , Mukonzo Jackson , Ntale Muhammad , Mubiri Paul , Bbosa Godfrey
3M ago
Background: Antiretroviral hair drug levels are currently being used to monitor adherence to HIV treatment. There is currently a dearth of literature on the preferred technique(s) of hair harvest for medical testing in the context of African multicultural settings. Objective: To explore the preferred techniques(s) of hair harvest for medical testing among TB patients. Methods: We used a descriptive phenomenological approach to conduct interviews for 15 TB patients from the 06th through the 24th of June 2022. Data was organized by N-VIVO version 10 and analysed step by step using a thematic ana ..read more
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Treatment outcomes and challenges of treating tuberculosis in children in a nomadic pastoralist community in Kenya
African Journals Online | African Health Sciences
by Limungi Godfrey M , Mburugu Patrick M , Kirigia Consolata , Orsolya Maté
3M ago
Background: Tuberculosis in children has remained a major cause of childhood morbidity and mortality, especially in the developing countries where it has been associated with marginalization, vulnerability and poverty. Study objectives: To evaluate treatment outcomes and determine the challenges experienced by health providers while treating tuberculosis in children in a nomadic pastoralist community in Kenya. Methods: This was a descriptive cross sectional study design utilizing mixed methods, conducted at Lodwar County Referral Hospital in Turkana County- Kenya. We utilized census sampling m ..read more
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