Comprehensive Meta-Analysis Supports Use of CBT for the Treatment of Depression
Psychiatry Advisor
by Aleta Terrill
4h ago
According to a comprehensive meta-analysis published in World Psychiatry, cognitive behavior therapy (CBT) was an effective treatment for depression across subgroups of patients and in different settings. However, its comparative efficacy remained unclear. Investigators from the Vrije Universiteit Amsterdam in The Netherlands searched publication databases through January 2022 for randomly assigned controlled trials evaluating CBT for the treatment of depression. The investigators defined CBT as work with a therapist focusing on the effects dysfunctional thoughts on behavior and functioning co ..read more
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Limited Drug Exposure Data Halt Accelerated Approval Attempt for Donanemab
Psychiatry Advisor
by Diana Ernst, RPh
4h ago
The Food and Drug Administration (FDA) has issued a Complete Response Letter (CRL) to Eli Lilly regarding the application for accelerated approval for donanemab, an investigational therapy for early symptomatic Alzheimer disease. Donanemab is an antibody therapy that targets a modified form of deposited amyloid-β peptide called N3pG. The accelerated approval application was based on data from the phase 2 TRAILBLAZER-ALZ trial (ClinicalTrials.gov Identifier: NCT03367403), which evaluated the efficacy and safety of donanemab in patients with early symptomatic Alzheimer disease who had tau a ..read more
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Canadian Province Decriminalizes Small Amounts of Hard Drugs
Psychiatry Advisor
by Haymarket Media
4h ago
HealthDay News— To fight an urgent opioid overdose crisis, a Canadian province took an unusual step on Tuesday. British Columbia decriminalized small amounts of several hard drugs. This includes up to 2.5 g of cocaine, heroin, and fentanyl, the province’s Ministry of Mental Health and Addictions said in a statement. Going forward, police will not seize the drugs. Instead, adults found with that amount will be given information about addiction treatment programs. “We know criminalization drives people to use alone. Given the increasingly toxic drug supply, using alone can be fatal,” Jennifer Wh ..read more
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Nearly Half of People With Dementia Experience a Fall Annually
Psychiatry Advisor
by Haymarket Media
4h ago
HealthDay News — Nearly half of people with dementia experienced a fall in 2016, according to a study published online Jan. 12 in Alzheimer’s & Dementia. Safiyyah M. Okoye, Ph.D., from the Johns Hopkins University School of Nursing in Baltimore, and colleagues used data from the 2015 and 2016 National Health and Aging Trends Study to identify fall-risk factors among community-living older adults aged 65 years and older with and without dementia (5,581 individuals). The researchers found that fall rates were higher among people living with dementia versus those without dementia (45.5 versus ..read more
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Biden to Lift COVID-19 Emergencies in May
Psychiatry Advisor
by Haymarket Media
6h ago
HealthDay News — The two COVID-19 emergency measures declared by the White House at the start of the pandemic will end in May. President Joe Biden informed Congress of the plan on Monday, as part of a statement opposing House Republicans’ plan to immediately end the protections. “An abrupt end to the emergency declarations would create wide-ranging chaos and uncertainty throughout the health care system — for states, for hospitals and doctors’ offices, and, most importantly, for tens of millions of Americans,” the Office of Management and Budget explained in the statement. Instead, the Biden a ..read more
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Severe Obstructive Sleep Apnea May Lead to Worse Post-Stroke Prognosis
Psychiatry Advisor
by Emily Estrada
21h ago
In the setting of acute ischemic stroke, severe obstructive sleep apnea (OSA) was associated with poorer functional outcomes than non-severe OSA, according to a small study published in the journal Sleep Medicine. High comorbidity between stroke and OSA has been reported, however, it remains unclear whether the severity of OSA affects functional outcomes. For the study, researchers assessed the impact of OSA on functional prognosis in the acute phase of stroke and examined quantitative electroencephalography (EEG) markers during sleep in patients with stroke. The study was conducted at the Sec ..read more
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Receiving an Opioid Prescription Increases Opioid Use Disorder Risk by 7-Fold
Psychiatry Advisor
by Aleta Terrill
21h ago
Receipt of a single opioid prescription was found to result in a substantially increased risk of developing opioid use disorder (OUD) among the general population, according to results of a study published in Psychological Medicine. A team of investigators sourced data for this study from national linked registries in Sweden. Individuals (N=1,516,392) born in Sweden between 1980 and 2000 were evaluated for receipt of an opioid prescription and subsequent OUD risk through 2017. To balance for cohort differences, propensity score matching and co-sibling analyses were performed. A total of 335,83 ..read more
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Increase in Cannabis-Related Emergency Visits for Older Adults Identified From 2005 to 2019
Psychiatry Advisor
by Haymarket Media
21h ago
HealthDay News — The rate of cannabis-related emergency department visits increased significantly for adults aged 65 years and older from 2005 to 2019, according to a study published online Jan. 9 in the Journal of the American Geriatrics Society. Benjamin H. Han, M.D., from University of California San Diego, and colleagues examined trends in cannabis-related emergency department visits among older adults. The analysis included data from all acute care hospitals in California from 2005 to 2019. The researchers found that the cannabis-related emergency department visit rate increased from 20.7 ..read more
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FDA Could Ease Blood Donation Rules for Gay Men
Psychiatry Advisor
by Haymarket Media
21h ago
HealthDay News — Longstanding restrictions on blood donations from gay or bisexual men could soon shift toward a more nuanced policy, where such men are asked about sexual partners and practices instead, the U.S. Food and Drug Administration announced Friday. Specifically, gay men who are in monogamous relationships will no longer be required to abstain from sex for any period of time before donating to the nation’s blood supply. Old rules in place since the 1980s had made such demands, out of fears of possible HIV contamination of donated blood. But pressure from LGBT organizations, improveme ..read more
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ADHD Risk Not Related With Prenatal Benzodiazepine or Z-Hypnotic Exposure
Psychiatry Advisor
by Aleta Terrill
2d ago
Prenatal exposure to benzodiazepines or z-hypnotics likely has little impact on childhood attention-deficit/hyperactivity disorder (ADHD) risk, according to results of a study published in JAMA Network Open. Investigators from the University of Oslo and the Norwegian Institute of Public Health sourced data for this prospective cohort study from the population-based Mother, Father and Child Cohort Study (MoBa) which pooled data from linked Norwegian registries. Pregnant women and their families were recruited for MoBa between 1999 and 2008. Mother-offspring dyads (n=82,201) were evaluated for t ..read more
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