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An unusual case of primary splenic soft part alveolar sarcoma: case report and review of the literature with emphasis on the spectrum of TFE3-associated neoplasms

BioMed Central » Diagnostic Pathology

by René Guérin, Anne-Lise Menard, Emilie Angot, Nicolas Piton, Pierre Vera, Lilian Schwarz, Jean-Christophe Sabourin, Marick Laé and Pierre-Alain Thiébaut

5d ago

Alveolar soft part sarcoma is a rare tumour of soft tissues, mostly localized in muscles or deep soft tissues of the extremities. In rare occasions, this tumour develops in deep tissues of the abdomen or pelvis ..read more

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A case of pancreatic PEComa with prominent inflammatory cell infiltration: the inflammatory subtype is a distinct histologic group of PEComa

BioMed Central » Diagnostic Pathology

by Hikaru Tsukita, Kei Koyama, Takahiro Ishinari, Ayana Takahashi, Ken Miyabe, Michinobu Umakoshi, Makoto Yoshida, Yukitsugu Kudo-Asabe, Akiko Nishida, Naohiko Otsuka, Ouki Yasui, Ikuma Kato, Noriyoshi Fukushima and Akiteru Goto

1w ago

PEComa is a mesenchymal tumor that can occur in various organs including the uterus and soft tissues. PEComas are composed of perivascular epithelioid cells, and angiomyolipoma (AML), clear cell sugar tumor (C ..read more

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Development of crizotinib-associated renal cyst in a non-small cell lung cancer patient with ALK fusion: a case report and review of the literature

BioMed Central » Diagnostic Pathology

by Peng Zhang, JiaHua Xu, Qing Wu, Jianxin Qian and Song Wang

1w ago

Crizotinib, an oral first-generation tyrosine kinase inhibitor (TKI), is superior to systemic chemotherapy for the treatment of non-small cell lung cancer (NSCLC) with positive rearrangement of anaplastic lymp ..read more

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Clinicopathological analysis of 22 Müllerian adenosarcomas and the sequencing of DICER1 mutation

BioMed Central » Diagnostic Pathology

by Xiaohong Yao, Wei Wang and Ying He

3w ago

Müllerian adenosarcoma, a rare malignancy, presents diagnostic and therapeutic challenges. In this study, we conducted an analysis of the clinicopathological characteristics of 22 adenosarcomas, with a particu ..read more

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Concurrent KRAS p.G12C mutation and ANK3::RET fusion in a patient with metastatic colorectal cancer: a case report

BioMed Central » Diagnostic Pathology

by Tillmann Bedau, Carina Heydt, Udo Siebolts, Thomas Zander, Max Kraemer, Heike Loeser, Reinhard Buettner and Alexander Quaas

1M ago

Colorectal cancer (CRC) frequently involves mutations in the KRAS gene, impacting therapeutic strategies and prognosis. The occurrence of KRAS mutations typically precludes the presence of RET fusions, with curre ..read more

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Comprehensive evaluation of the relationship between biomarker profiles and neoadjuvant chemotherapy outcomes for breast cancer patients

BioMed Central » Diagnostic Pathology

by Mijia Wang, Zhendong Wei, Jixia Kong and Haidong Zhao

1M ago

Accurately predicting the response to neoadjuvant chemotherapy (NAC) in breast cancer patients is crucial for guiding treatment strategies and enhancing clinical outcomes. Current studies have primarily focuse ..read more

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Extradural spinal melanoma: is it primary or metastatic? A case report with a brief review of literature

BioMed Central » Diagnostic Pathology

by Raghav Kapoor, Anurag Mehta, Anila Sharma, Shrinidhi Nathany, Himanshi Diwan and Divya Bansal

1M ago

Melanocytic lesions involving the central nervous system are extremely rare and pose a diagnostic challenge owing melanoma being the third most common malignancy metastasizing to the spine. Morphology and immu ..read more

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High incidence of HPV infection in minors with oral squamous cell carcinoma

BioMed Central » Diagnostic Pathology

by Ningxiang Wu, Yonghui Li, Xiaokun Ma, Zhen Huang, Zhuoxuan Chen, Weihua Chen and Ran Zhang

1M ago

Oral squamous cell carcinoma in minors is considered to be a distinct entity from OSCC in older patients, with an uncertain etiology. Human papillomavirus (HPV) infection may trigger the initiation and promote ..read more

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Two lymphoma histotypes and papillary thyroid carcinoma coexisting on Hashimoto ground: a case report and review of the literature

BioMed Central » Diagnostic Pathology

by Igor Iskra, Maja Ilić Tomaš, Tatjana Bogović Crnčić, Edvin Kukić, Ita Hadžisejdić, Manuela Avirović and Neva Girotto

1M ago

Papillary carcinoma is the most frequent type of thyroid carcinoma, while primary thyroid lymphoma is uncommon disease. The coexistence of these entities has already been described, and the common risk factor ..read more

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Histological criteria for selecting patients who need clonality test for non-gastric MALT lymphoma diagnosis

BioMed Central » Diagnostic Pathology

by Dajeong Park and Junhun Cho

1M ago

The histological diagnosis of extranodal marginal zone lymphoma of the mucosa-associated lymphoid tissue (MALT lymphoma) is difficult for pathologists. Recently, digital pathology systems have been widely used ..read more

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