Measuring EQ-5D-5L utility values in parents who have experienced perinatal death
The European Journal of Health Economics
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22h ago
Abstract Background Policymakers use clinical and cost-effectiveness evidence to support decisions about health service commissioning. In England, the National Institute for Health and Care Excellence (NICE) recommend that in cost-effectiveness analyses “effectiveness” is measured as quality-adjusted life years (QALYs), derived from health utility values. The impact of perinatal death (stillbirth/neonatal death) on parents’ health utility is currently unknown. This knowledge would improve the robustness of cost-effectiveness evidence for policymakers. Objective This study aimed to estimate the ..read more
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Unravelling risk selection in Spanish general government employee mutual funds: evidence from cancer hospitalizations in the public health network
The European Journal of Health Economics
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6d ago
Abstract Government employees in Spain are covered by public Mutual Funds that purchase a uniform basket of benefits, equal to the ones served to the general population, from private companies. Companies apply as private bidders for a fixed per capita premium hardly adjusted by age. Our hypothesis is that this premium does not cover risks, and companies have incentives for risk selection, which are more visible in high-cost patients. We focus on a particularly costly disease, cancer, whose prevalence is similar among government employees and the general population. We compare hospitalisations ..read more
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Validity and responsiveness of EQ-5D-Y in children with haematological malignancies and their caregivers
The European Journal of Health Economics
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1w ago
Abstract The psychometric properties of the EQ-5D-Y have not been widely tested in severely ill children. The aim of this study was to assess and compare the validity and responsiveness of the EQ-5D-Y-3L and EQ-5D-Y-5L in paediatric inpatients with haematological malignancies and caregivers. Respondents completed the interviewer-administered self-complete or proxy version of the EQ-5D-Y-3L and EQ-5D-Y-5L and an overall health assessment twice on different days. Known-groups validity was assessed by comparing patients who differed in overall health and Eastern Cooperative Oncology Group (ECOG ..read more
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Comparing heuristic valuation processes between health state valuation from child and adult perspectives
The European Journal of Health Economics
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3w ago
Abstract Objectives Health state valuation assumes that respondents trade off between all aspects of choice tasks and maximize their utility. Yet, respondents may use heuristic valuation processes, i.e., strategies to simplify or avoid the trade-offs that are core to health state valuation. The objective of this study is to explore if heuristic valuation processes are more prevalent for valuation from a 10-year-old child’s perspective compared to the use of an adult perspective. Methods We reused existing data in which EQ-5D health states were valued from adult and child perspectives with ..read more
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A Spanish value set for the SF-6D based on the SF-12 v1
The European Journal of Health Economics
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3w ago
Abstract Aim This paper reports the first estimation of an SF-6D value set based on the SF-12 for Spain. Methods A representative sample (n = 1020) of the Spanish general population valued a selection of 56 hypothetical SF-6D health states by means of a probability lottery equivalent (PLE) method. The value set was derived using both random effects and mean models estimated by ordinary least squares (OLS). The best model was chosen on the basis of its predictive ability assessed in terms of mean absolute error (MAE). Results The model yielding the lowest MAE (0.075) was that based on main effe ..read more
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Pragmatic randomized controlled trial comparing a complex telemedicine-based intervention with usual care in patients with chronic conditions
The European Journal of Health Economics
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3w ago
Abstract This study evaluates a complex telemedicine-based intervention targeting patients with chronic health problems. Computer tablets and home telemonitoring devices are used by patients to report point-of-care measurements, e.g., blood pressure, blood glucose or oxygen saturation, and to answer health-related questions at a follow-up center. We designed a pragmatic randomized controlled trial to compare the telemedicine-based intervention with usual care in six local centers in Norway. The study outcomes included health-related quality of life (HRQoL) based on the EuroQol questionnaire (E ..read more
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The Economic Costs of Informal Care: Estimates from a National Cross-Sectional Survey in The Netherlands
The European Journal of Health Economics
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3w ago
Abstract Faced with an unprecedented demand for long-term care, European health care systems are moving towards mixed care models, where the welfare state and informal caregivers share care responsibilities. While informal care is often viewed as a means of alleviating pressure on public care, it comes with significant economic costs for caregivers, their employers, and society at large. This study uses nationally representative data to estimate the total direct (informal care time and out-of-pocket costs) and indirect (productivity) economic costs of informal care in the Netherlands in 2019 ..read more
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Screening strategy to advance HCV elimination in Italy: a cost-consequence analysis
The European Journal of Health Economics
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1M ago
Abstract Background and Aims Italy has the greatest burden of hepatitis C virus (HCV) infection in Western Europe. The screening strategy represents a crucial prevention tool to achieve HCV elimination in Italy. We evaluated the cost-consequences of different screening strategies for the diagnosis of HCV active infection in the birth cohort 1948–1968 to achieve the HCV elimination goal. Methods We designed a probabilistic model to estimate the clinical, and economic outcomes of different screening coverage uptakes, considering the direct costs of HCV management according to each liver&nbs ..read more
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On spillovers in economic evaluations: definition, mapping review and research agenda
The European Journal of Health Economics
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1M ago
Abstract An important issue in economic evaluations is determining whether all relevant impacts are considered, given the perspective chosen for the analysis. Acknowledging that patients are not isolated individuals has important implications in this context. Increasingly, the term “spillovers” is used to label consequences of health interventions on others. However, a clear definition of spillovers is lacking, and as a result, the scope of the concept remains unclear. In this study, we aim to clarify the concept of spillovers by proposing a definition applicable in health economic evaluations ..read more
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AOTMiT reimbursement recommendations compared to other HTA agencies
The European Journal of Health Economics
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1M ago
Abstract Our objective was to compare AOTMiT (Polish: Agencja Oceny Technologii Medycznych i Taryfikacji) recommendations to other HTA (Health Technology Assessment) agencies for newly registered drugs and new registration indications issued by the European Medicines Agency between 2014 and 2019. The study aims to assess the consistency and justifications of AOTMiT recommendations compared to that of other HTA agencies in 11 countries. A total of 2494 reimbursement recommendations published by 12 HTA agencies for 464 medicinal products and 525 indications were analyzed. Our analysis confirmed ..read more
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