Scientists reveal how ETV4 controls stem cell differentiation in response to mechanical cues ..read more

Aging clocks can measure the biological age of humans with high precision. Biological age can be influenced by environmental factors such as smoking or diet, thus deviating from the chronological age that is calculated using the date of birth. The precision of these aging clocks suggests that the aging process follows a program. Scientists have now discovered that aging clocks actually measure the increase in stochastic changes in cells ..read more

Scientists report significant progress in cultivating nephron progenitor cells (NPCs), the cells destined to form the kidney's filtration system, the nephrons. NPCs hold immense promise for understanding kidney development, modeling diseases, and discovering new treatments. The team improved the chemical cocktail for generating and growing NPCs in the laboratory, enabling the sustained growth of both mouse and human NPCs in a simple 2-dimensional format ..read more

Researchers have found a way to better control the preclinical generation of key neurons depleted in Parkinson's disease, pointing toward a new approach for a disease with no cure and few effective treatments ..read more

Physical cues in the womb, and not just genetics, influence the normal development of neural crest cells, the embryonic stem cells that form facial features, finds a new study ..read more

Neural crest cells -- embryonic pluripotent cells within the facial primordium -- may be necessary for forming proper animal facial structures. Researchers have produced neural crest cell-rich aggregates from human pluripotent stem cells and developed a method to differentiate them in cell populations with a branchial arch-like gene expression pattern ..read more

University of Montana researchers and their partners have found a new method to generate human cartilage of the head and neck ..read more

Researchers have succeeded in correcting a gene defect that causes a hereditary liver disease and its adverse effects on cells ..read more

A traumatic brain injury (TBI) can quadruple your risk for developing dementia and increase your chances of developing neurodegenerative diseases such as ALS. In a new study scientists use lab-grown human brain structures known as organoids to offer insights into why this is the case and how to mitigate the risk ..read more

Familial Alzheimer's disease can be transferred via bone marrow transplant, researchers show. When the team transplanted bone marrow stem cells from mice carrying a hereditary version of Alzheimer's disease into normal lab mice, the recipients developed Alzheimer's disease -- and at an accelerated rate ..read more