Rare disease research at Cambridge receives major boost with launch of two new centres
University of Cambridge
by cjb250
12h ago
The virtual centres, supported by the charity LifeArc, will focus on areas where there are significant unmet needs. They will tackle barriers that ordinarily prevent new tests and treatments reaching patients with rare diseases and speed up the delivery of rare disease treatment trials. The centres will bring together leading scientists and rare disease clinical specialists from across the UK for the first time, encouraging new collaborations across different research disciplines and providing improved access to facilities and training. LifeArc Centre for Rare Mitochondrial Diseases Professo ..read more
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Training AI models to answer ‘what if?’ questions could improve medical treatments
University of Cambridge
by sc604
4d ago
Artificial intelligence techniques can be helpful for multiple medical applications, such as radiology or oncology, where the ability to recognise patterns in large volumes of data is vital. For these types of applications, the AI compares information against learned examples, draws conclusions, and makes extrapolations. Now, an international team led by researchers from Ludwig-Maximilians-Universität München (LMU) and including researchers from the University of Cambridge, is exploring the potential of a comparatively new branch of AI for diagnostics and therapy. The researchers found that ..read more
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Mess is best: disordered structure of battery-like devices improves performance
University of Cambridge
by sc604
5d ago
Researchers led by the University of Cambridge used experimental and computer modelling techniques to study the porous carbon electrodes used in supercapacitors. They found that electrodes with a more disordered chemical structure stored far more energy than electrodes with a highly ordered structure. Supercapacitors are a key technology for the energy transition and could be useful for certain forms of public transport, as well as for managing intermittent solar and wind energy generation, but their adoption has been limited by poor energy density. The researchers say their results, reporte ..read more
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Steven Barrett appointed Regius Professor of Engineering
University of Cambridge
by sc604
5d ago
Professor Steven Barrett has been appointed Regius Professor of Engineering at the University of Cambridge, effective 1 June. He joins the University from the Massachusetts Institute of Technology (MIT), where he is head of the Department of Aeronautics and Astronautics (AeroAstro). Barrett’s appointment marks his return to Cambridge, where he was an undergraduate at Pembroke College, and received his PhD. He was a Lecturer in the Department of Engineering from 2008 until 2010, when he joined the faculty at MIT. The Regius Professorships are royal academic titles created by the monarch. The ..read more
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AI speeds up drug design for Parkinson’s ten-fold
University of Cambridge
by sc604
5d ago
The researchers, from the University of Cambridge, designed and used an AI-based strategy to identify compounds that block the clumping, or aggregation, of alpha-synuclein, the protein that characterises Parkinson’s. The team used machine learning techniques to quickly screen a chemical library containing millions of entries, and identified five highly potent compounds for further investigation. Parkinson’s affects more than six million people worldwide, with that number projected to triple by 2040. No disease-modifying treatments for the condition are currently available. The process of scr ..read more
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Interspecies competition led to even more forms of ancient human – defying evolutionary trends in vertebrates
University of Cambridge
by fpjl2
5d ago
Climate has long been held responsible for the emergence and extinction of hominin species. In most vertebrates, however, interspecies competition is known to play an important role. Now, research shows for the first time that competition was fundamental to 'speciation' – the rate at which new species emerge – across five million years of hominin evolution. The study, published today in Nature Ecology & Evolution, also suggests that the species formation pattern of our own lineage was closer to island-dwelling beetles than other mammals.   “We have been ignoring the way competi ..read more
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Is Democracy Dying?
University of Cambridge
by Anonymous
1w ago
2024 is the year of elections. A record number of elections will take place, with half the adult population of the world, some two billion people, having the chance to vote. Is this a milestone to be celebrated in our democratic history or are we at a crossroads where the fate of liberal democracy hangs in the balance? Against a backdrop of polarising populist movements, the erosion of trust in traditional institutions and a decline of democratic norms, we ask: is democracy dying? Is the election of populists an expression of democracy or a breakdown of democracy? How resilient are our democ ..read more
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Study unpicks why childhood maltreatment continues to impact on mental and physical health into adulthood
University of Cambridge
by cjb250
1w ago
Individuals who experienced maltreatment in childhood – such as emotional, physical and sexual abuse, or emotional and physical neglect – are more likely to develop mental illness throughout their entire life, but it is not yet well understood why this risk persists many decades after maltreatment first took place. In a study published in Proceedings of the National Academy of Sciences, scientists from the University of Cambridge and Leiden University found that adult brains continue to be affected by childhood maltreatment in adulthood because these experiences make individuals more likely ..read more
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Four Cambridge researchers awarded prestigious European Research Council Advanced Grants
University of Cambridge
by jg533
1w ago
The European Research Council (ERC) has announced today the award of 255 Advanced Grants to outstanding research leaders across Europe, as part of the EU’s Horizon Europe programme. Four University of Cambridge researchers are amongst those to receive this prestigious and competitive funding. The University of Cambridge’s grant awardees are: Professor Albert Guillén i Fàbregas in the Department of Engineering for his project Scaling and Concentration Laws in Information Theory. Guillén i Fàbregas, who has previously received ERC Starting, Consolidator and Proof of Concept Grants, said ..read more
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Pork labelling schemes ‘not helpful’ in making informed buying choices, say researchers
University of Cambridge
by jg533
1w ago
Researchers have evaluated different types of pig farming – including woodland, organic, free range, RSPCA assured, and Red Tractor certified, to assess each systems’ impact across four areas: land use (representing biodiversity loss), greenhouse gas emissions, antibiotics use and animal welfare. Their study concludes that none of the farm types performed consistently well across all four areas – a finding that has important implications for increasingly climate conscious consumers, as well as farmers themselves. However, there were individual farms that did perform well in all domains, incl ..read more
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