
TWiV
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A podcast about viruses - the kind that make you sick. MicrobeTV is an independent podcast network for people who are interested in the sciences. Our shows are about science: viruses, microbes, parasites, evolution, urban agriculture, communication, and engineering.
TWiV
3y ago
Kartik, Denise, and Gorka join TWiV to discuss their finding that changes in the surface glycoprotein of South American yellow fever virus lead to reduced neutralization by antibodies induced by the vaccine, which is derived from an African isolate.
Hosts: Vincent Racaniello, Dickson Despommier, and Brianne Barker
Guests: Kartik Chandran, Denise Haslwanter, and Gorka Lasso Cabrera
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Download TWiV 893 (65 MB .mp3, 108 min)
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Pr ..read more
TWiV
3y ago
In COVID-19 clinical update #111, Dr. Griffin discusses vaccine coverage and mortality in Hong Kong, immune response to boosters in kids, hospitalization of kids, breath based diagnostic test, viral co-infections, bivalent mRNA vaccine, intramuscular Evusheld, and global long COVID.
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Download TWiV 892 (33 MB .mp3, 54 min)
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Vaccine coverage and mortality, Hong Kong (MMWR)
Kids behind on routine vaccinations (Politico)
Immune respons ..read more
TWiV
3y ago
Elke, Adam, and Gabor join TWiV to discuss their work on Lloviu virus, a filovirus, including recovery of infectious virus from a DNA copy of the genome and from Schreiber’s bats in Hungary.
Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker
Guests: Elke Muhlberger, Adam Hume, and Gabor Kemenesi
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Download TWiV 891 (65 MB .mp3, 108 min)
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Elke on TWiV 200 and Threading the NEIDL
Infectious Lloviu virus ..read more
TWiV
3y ago
This episode of TWiV is focused on COVID-19 vaccines and antibodies: who should get boosters, whether a variant matched mRNA vaccine is superior to a historical vaccine, and how the interval between vaccination and infection influences the quality of the antibody response.
Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Brianne Barker
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Download TWiV 888 (65 MB .mp3, 108 min)
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What next for COVID-19 boosters ..read more
TWiV
3y ago
In COVID-19 clinical update #110, Dr. Griffin covers hospital admissions during variant outbreaks, viral load in vaccinated and unvaccinated individuals, predictive capacity of symptoms in children, comparison of antigen tests, incidence of myocarditis after vaccination, steroids during replication phase, Paxlovid efficacy and safety, fluvoxamine, sabizabutin, colchicine, and prevalence of infection in Africa.
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Download TWiV 889 (52 MB .mp3, 53 min)
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Lin ..read more
TWiV
3y ago
Richard joins TWiV to discuss the SARS-CoV-2 antiviral drug Molnupiravir , including how it was discovered, its mechanism of action, whether it is a mutagen for cells, and the future of drugs for treatment of COVID-19.
Hosts: Vincent Racaniello, Alan Dove, and Brianne Barker
Guest: Richard Plemper
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Download TWiV 888 (65 MB .mp3, 108 min)
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Richard on TWiV 636
Molnupiravir in ferrets (Nat Micro)
Oral prodrug of Remdesivir in f ..read more
TWiV
3y ago
TWiV explains why this season’s influenza vaccine is not protecting against mild to moderate disease caused by H3N2 virus, and that antibody-dependent entry of SARS-CoV-2 into monocytes is a major contributor to severe COVID-19.
Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Amy Rosenfeld
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Download TWiV 887 (65 MB .mp3, 108 min)
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Seasonal influenza vaccine effectiveness (MMWR)
Properties of a dominant H3N2 v ..read more
TWiV
3y ago
In COVID-19 clinical update #109, Daniel Griffin discusses cardiac complications after infection or vaccination, long COVID in children, fourth vaccine dose in Israel, no need for fourth vaccine does in EU, dexamethasone dosing, immunomodulation therapy, MIS outcomes in children, US long COVID effort launched, and herd immunity.
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Download TWiV 886 (27 MB .mp3, 45 min)
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Cardiac complications after infection or vaccination (MMWR)
Lo ..read more
TWiV
3y ago
TWiV reveals an ACE2-dependent sarbecovirus from Russian bats that is not inhibited by anti-SARS-CoV-2 antibodies, and a modified vaccinia virus Ankara vectored vaccine that protects nonhuman primates from Delta infection.
Hosts: Vincent Racaniello, Rich Condit, and Brianne Barker
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Download TWiV 885 (73 MB .mp3, 122 min)
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Sarbecovirus from Russian bat (bioRxiv) 1:33
MVA vectored COVID vaccine (Sci Immunol) 30:19
Letters read ..read more
TWiV
3y ago
Vincent and Amy explain how asthmatic bronchial smooth muscle increases rhinovirus replication in the bronchial epithelium, and mimicry of IL-17 by the ORF8 protein of SARS-CoV-2.
Hosts: Vincent Racaniello and Amy Rosenfeld
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Download TWiV 884 (73 MB .mp3, 122 min)
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Asthmatic bronchial smooth muscle and rhinovirus (Cell Rep)
SARS-CoV-2 ORF8 mimics IL-17 (mBio)
Letters read on TWiV 884
Timestamps by Jolene. Thanks!
Weekly Pic ..read more