
BMC Bioinformatics
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BMC Bioinformatics is an open access, peer-reviewed journal that considers articles on all aspects of the development, testing and novel application of computational and statistical methods for the modeling and analysis of all kinds of biological data, as well as other areas of computational biology.
BMC Bioinformatics
1d ago
Massively parallel reporter assays (MPRAs) are an experimental technology for measuring the activity of thousands of candidate regulatory sequences or their variants in parallel, where the activity of individu ..read more
BMC Bioinformatics
1d ago
The global Coronavirus Disease 2019 (COVID-19) pandemic highlighted the need to quickly diagnose infections to identify and prevent viral spread in the population. In response to the pandemic, BioFire Defense ..read more
BMC Bioinformatics
1d ago
Piwi-interacting RNAs (piRNAs) are well established for monitoring and protecting the genome from transposons in germline cells. Recently, numerous studies provided evidence that piRNAs also play important rol ..read more
BMC Bioinformatics
4d ago
Data adjustment is an essential tool for increasing statistical power during analysis, for example in case of complex multi-experiment data from (single-cell) RNA, proteomics and other omics data. Despite its ..read more
BMC Bioinformatics
4d ago
Alterations of metabolism, including changes in mitochondrial metabolism as well as glutathione (GSH) metabolism are a well appreciated hallmark of many cancers. Mitochondrial GSH (mGSH) transport is a poorly ..read more
BMC Bioinformatics
4d ago
A massive amount of protein sequences have been obtained, but their functions remain challenging to discern. In recent research on protein function prediction, Protein-Protein Interaction (PPI) Networks have p ..read more
BMC Bioinformatics
4d ago
Single-cell technologies enable comprehensive profiling of diverse immune cell-types through the measurement of multiple genes or proteins per individual cell. In order to translate immune signatures assayed f ..read more
BMC Bioinformatics
6d ago
Fluorescent Timer proteins, which display time-dependent changes in their emission spectra, are invaluable for analyzing the temporal dynamics of cellular events at the single-cell level. We previously develop ..read more
BMC Bioinformatics
6d ago
BMC Bioinformatics
6d ago
Proteins are involved in nearly all cellular functions, encompassing roles in transport, signaling, enzymatic activity, and more. Their functionalities crucially depend on their complex three-dimensional arran ..read more