Diffusion MRI relates to plasma Aβ42/40 in PET negative participants without dementia
Department of Neurology » College of Medicine » University of Florida
by Leslie Merryman
23h ago
Congratulations to Drs. David Vaillancourt, Melissa Armstrong and Karen McFarland on the publication of “Diffusion MRI relates to plasma Aβ42/40 in PET negative participants without dementia,” which appears in the March edition of Alzheimer’s and Dementia. Abstract Magnetic resonance imaging (MRI) biomarkers are needed for indexing early biological stages of Alzheimer’s disease (AD), such as plasma amyloid‐β (Aβ42/40) positivity in Aβ positron emission tomography (PET) negative individuals. METHODS Diffusion free‐water (FW) MRI was acquired in individuals with normal cognition (NC) and mild co ..read more
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U.S. Tax Credits to Promote Practical Proactive Preventative Care for Parkinson’s Disease
Department of Neurology » College of Medicine » University of Florida
by Leslie Merryman
23h ago
Congratulations to Dr. Michael Okun on the publication of his position paper “U.S. Tax Credits to Promote Practical Proactive Preventative Care for Parkinson’s Disease,” which appears in the March edition of the Journal of Parkiinson’s Disease. Abstract Persons with Parkinson’s disease (PD) and society at large can profit from a strategic investment into a forward leaning, practical, preventative, and proactive multidisciplinary care policy. The American healthcare system is not easily bent to accommodate this type of care, and thus a tax benefit is an attractive option. An individual federal ..read more
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Rhythmic Jaw Movements in Amyotrophic Lateral Sclerosis: Is It Clonus or Tremor?
Department of Neurology » College of Medicine » University of Florida
by Leslie Merryman
3d ago
Congratulations to Dr. Aparna Shukla on the publication of “Rhythmic Jaw Movements in Amyotrophic Lateral Sclerosis: Is It Clonus or Tremor?,” which appears as a video abstract in Tremor and other Hyperkinetic Movements. Abstract Background: Jaw clonus refers to involuntary, rhythmic jaw contractions induced by a hyperactive trigeminal nerve stretch reflex; however, the movements, when triggered without a stretch, can be confused with a tremor. Phenomenology Shown: This video demonstrates a patient with amyotrophic lateral sclerosis presenting with rapid rhythmic jaw movements seen a ..read more
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Neuromodulation for the treatment of Prader-Willi syndrome – A systematic review
Department of Neurology » College of Medicine » University of Florida
by Leslie Merryman
6d ago
Congratulations to Drs. Michael S. Okun, Kelly D. Foote, and Aysegul Gunduz, on the publication of ” Neuromodulation for the treatment of Prader-Willi syndrome – A systematic review,” which appears in the April edition of Neurotherapeutics. Abstract Prader-Willi syndrome (PWS) is a complex, genetic disorder characterized by multisystem involvement, including hyperphagia, maladaptive behaviors and endocrinological derangements. Recent developments in advanced neuroimaging have led to a growing understanding of PWS as a neural circuit disorder, as well as subse ..read more
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Longitudinal Free-Water Changes in Dementia with Lewy Bodies
Department of Neurology » College of Medicine » University of Florida
by Leslie Merryman
1w ago
Congratulations to Drs. Shannon Chiu, Melissa Armstrong and David Vaillancourt on the publication of ” Longitudinal Free-Water Changes in Dementia with Lewy Bodies,” which was published in March 2024 edition of Movement Disorders. Abstract Background: Diffusion-weighted magnetic resonance imaging (dMRI) examines tissue microstructure integrity in vivo. Prior dementia with Lewy bodies (DLB) diffusion tensor imaging studies yielded mixed results. Objective: We employed free-water (FW) imaging to assess DLB progression and correlate with clinical decline in DLB. Methods: Baseline a ..read more
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UF-led study could lead to new way to detect brain changes associated with Alzheimer’s risk
Department of Neurology » College of Medicine » University of Florida
by Leslie Merryman
1w ago
New research published today suggests there is a link between abnormal blood levels of amyloid — a protein associated with Alzheimer’s disease — and subtle changes in brain microstructures on a type of MRI, findings that could lead to a new way to detect Alzheimer’s earlier in people with no clinical signs. Researchers analyzed the results of 128 human participants with and without dementia from the 1Florida Alzheimer’s Disease Research Center who underwent imaging scans using an established diagnostic tool called positron emission tomography, or PET, which can detect amyloid plaques ..read more
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When does memory loss merit dementia screening?
Department of Neurology » College of Medicine » University of Florida
by Leslie Merryman
1w ago
“It is crucial for folks to appreciate that, with aging, it is common to occasionally forget names or misplace items,” Dr. Michael S. Okun, director of Norman Fixel Institute for Neurological Diseases at University of Florida Health and medical advisor to the Parkinson’s Foundation, tells TODAY.com ..read more
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Congratulations to Dr. Abbas Babajani-Feremi on the Success of the MEG lab!
Department of Neurology » College of Medicine » University of Florida
by Leslie Merryman
2w ago
We are thrilled to share a significant update from the MEG Lab highlighting our strides in advancing clinical care. Over the past eight months since the initiation of our clinical service, our dedicated team has conducted MEG scans for a total of 52 patients, surpassing the national average. This achievement is a testament to the expertise and commitment of our team members who have worked tirelessly to provide cutting-edge diagnostic services to our patients. Notably, among these cases, we have provided care for 13 pediatric patients, underscoring our commitment to serving diverse patient pop ..read more
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Proceedings of the 11th Annual Deep Brain Stimulation Think Tank: Pushing the Forefront of Neuromodulation with Functional Network Mapping, Biomarkers for Adaptive DBS, Bioethical Dilemmas, AI-Guided Neuromodulation, and Translational Advancements
Department of Neurology » College of Medicine » University of Florida
by Leslie Merryman
2w ago
Congratulations to Drs. Kara A. Johnson, Kelly D. Foote, Michael S. Okun, and Joshua K. Wong on the publication of “Proceedings of the 11th Annual Deep Brain Stimulation Think Tank: Pushing the Forefront of Neuromodulation with Functional Network Mapping, Biomarkers for Adaptive DBS, Bioethical Dilemmas, AI-Guided Neuromodulation, and Translational Advancements,” which appears in the February 21, 2024 edition of Frontiers in Human Neuroscience. The Deep Brain Stimulation (DBS) Think Tank XI was held on August 9-11, 2023 in Gainesville, Florida with the theme of “Pushing the Forefront of Neurom ..read more
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Thalamic deep brain stimulation in traumatic brain injury: a phase 1, randomized feasibility study
Department of Neurology » College of Medicine » University of Florida
by Leslie Merryman
2w ago
Congratulations to Dr. Christopher Butson on the publication of “Thalamic deep brain stimulation in traumatic brain injury: a phase 1, randomized feasibility study,” which appears in the December 2023 issue of Nature Medicine. Abstract Converging evidence indicates that impairments in executive function and information-processing speed limit quality of life and social reentry after moderate-to-severe traumatic brain injury (msTBI). These deficits reflect dysfunction of frontostriatal networks for which the central lateral (CL) nucleus of the thalamus is a critical node. The primary objective o ..read more
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